STRINGSTRING
c5375 c5375 c0888 c0888 c0940 c0940 yccR yccR ruvA ruvA yegP yegP fis fis recG recG uvrD uvrD recQ recQ c5376 c5376
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
c5375Hypothetical protein. (52 aa)
c0888Hypothetical protein ybiI; Escherichia coli K-12 ortholog: b0803; Escherichia coli O157:H7 ortholog: z1024. (88 aa)
c0940Hypothetical protein ybiI; Escherichia coli K-12 ortholog: b0803; Escherichia coli O157:H7 ortholog: z1024. (71 aa)
yccRHypothetical protein yccR; Escherichia coli K-12 ortholog: b0959; Escherichia coli O157:H7 ortholog: z1309. (209 aa)
ruvAHolliday junction DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa)
yegPHypothetical protein yegP; Escherichia coli K-12 ortholog: b2080; Escherichia coli O157:H7 ortholog: z3249; Belongs to the UPF0339 family. Duplicated subfamily. (123 aa)
fisDNA-binding protein fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. (98 aa)
recGATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (704 aa)
uvrDDNA helicase II; Escherichia coli K-12 ortholog: b3813; Escherichia coli O157:H7 ortholog: z5330. (738 aa)
recQATP-dependent DNA helicase recQ; Escherichia coli K-12 ortholog: b3822; Escherichia coli O157:H7 ortholog: z5343. (611 aa)
c5376Hypothetical protein. (145 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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