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| | nuoH | NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa) |
| | nuoJ | NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I subunit 6 family. (184 aa) |
| | nuoK | NADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa) |
| | nuoL | NADH dehydrogenase I chain L; Escherichia coli K-12 ortholog: b2278; Escherichia coli O157:H7 ortholog: z3537. (613 aa) |
| | nuoM | NADH dehydrogenase I chain M; Escherichia coli K-12 ortholog: b2277; Escherichia coli O157:H7 ortholog: z3536. (509 aa) |
| | nuoN | NADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (485 aa) |
| | yehZ | Hypothetical protein yehZ precursor; Escherichia coli K-12 ortholog: b2131; Escherichia coli O157:H7 ortholog: z3380. (305 aa) |
| | yehX | Hypothetical ABC transporter ATP-binding protein yehX; Escherichia coli K-12 ortholog: b2129; Escherichia coli O157:H7 ortholog: z3378. (308 aa) |
| | yegM | Hypothetical protein yegM precursor; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (464 aa) |
| | c2517 | Periplasmic binding protein; Residues 1 to 330 of 330 are 99.39 pct identical to residues 1 to 332 of 332 from GenPept.129 : >gb|AAL67368.1|AF447814_36 (AF447814) iron-chelating periplasmic-binding protein [Escherichia coli]. (330 aa) |
| | emrE | EmrE protein; Methyl viologen resistance protein C; Escherichia coli K-12 ortholog: b0543; Escherichia coli O157:H7 ortholog: z1870. (170 aa) |
| | yebM | High-affinity zinc uptake system ATP-binding protein znuC; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (251 aa) |
| | ynjD | Hypothetical ABC transporter ATP-binding protein ynjD; Escherichia coli K-12 ortholog: b1756; Escherichia coli O157:H7 ortholog: z2788. (228 aa) |
| | btuC | Vitamin B12 transport system permease protein btuC; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity). (326 aa) |
| | btuD | Vitamin B12 transport ATP-binding protein btuD; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa) |
| | ynfJ | Putative chloride channel protein eriC-like; Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response; Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily. (438 aa) |
| | ydcU | Hypothetical ABC transporter permease protein ydcU; Escherichia coli K-12 ortholog: b1442; Escherichia coli O157:H7 ortholog: z2277. (313 aa) |
| | ydcT | Hypothetical ABC transporter ATP-binding protein ydcT; Escherichia coli K-12 ortholog: b1441; Escherichia coli O157:H7 ortholog: z2278; Belongs to the ABC transporter superfamily. (337 aa) |
| | c1820 | Hypothetical protein; Residues 4 to 90 of 122 are 72.41 pct identical to residues 18 to 104 of 282 from GenPept.129 : >gb|AAL21744.1| (AE008830) Salmonella iron transporter: fur regulated [Salmonella typhimurium LT2]. (122 aa) |
| | c1811 | Hypothetical protein; Residues 14 to 89 of 102 are 51.31 pct identical to residues 37 to 111 of 367 from GenPept.129 : >dbj|BAB49683.1| (AP003000) probable secretion protein [Mesorhizobium loti]. (102 aa) |
| | ycjV | Hypothetical ABC transporter ATP-binding protein ycjV; Escherichia coli K-12 ortholog: b1318; Escherichia coli O157:H7 ortholog: z2463; Belongs to the ABC transporter superfamily. (360 aa) |
| | c1761 | Acriflavine resistance protein A precursor; Escherichia coli K-12 ortholog: b0463; Escherichia coli O157:H7 ortholog: z2509; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (384 aa) |
| | c1652 | Conserved hypothetical protein; Escherichia coli O157:H7 ortholog: z1966. (340 aa) |
| | sitB | SitB protein; Residues 7 to 263 of 275 are 62.03 pct identical to residues 11 to 276 of 296 from SwissProt.40 : >sp|Q56953|YFEB_YERPE Chelated iron transport system membrane protein yfeB. (275 aa) |
| | sitC | SitC protein; Residues 1 to 276 of 285 are 65.94 pct identical to residues 2 to 277 of 294 from SwissProt.40 : >sp|Q56954|YFEC_YERPE Chelated iron transport system membrane protein yfeC. (285 aa) |
| | sitD | SitD protein; Residues 1 to 272 of 285 are 53.30 pct identical to residues 4 to 275 of 297 from SwissProt.40 : >sp|Q56955|YFED_YERPE Chelated iron transport system membrane protein yfeD. (285 aa) |
| | potA | Spermidine/putrescine transport ATP-binding protein potA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa) |
| | potB | Spermidine/putrescine transport system permease protein potB; Escherichia coli K-12 ortholog: b1125; Escherichia coli O157:H7 ortholog: z1830. (287 aa) |
| | potC | Spermidine/putrescine transport system permease protein potC; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (264 aa) |
| | csgE | Curli production assembly/transport component csgE precursor; May be involved in the biogenesis of curli organelles. (129 aa) |
| | csgF | Curli production assembly/transport component csgF precursor; May be involved in the biogenesis of curli organelles. (138 aa) |
| | efeU | Putative cytochrome; Uptake of Fe(2+) ions across the membrane. Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family. (255 aa) |
| | ompF | Outer membrane protein F precursor; Porin ompF; Escherichia coli K-12 ortholog: b0929; Escherichia coli O157:H7 ortholog: z1276; Belongs to the Gram-negative porin family. (362 aa) |
| | msbA | Probable transport ATP-binding protein msbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa) |
| | cydD | Transport ATP-binding protein cydD; Escherichia coli K-12 ortholog: b0887; Escherichia coli O157:H7 ortholog: z1231. (588 aa) |
| | cydC | Transport ATP-binding protein cydC; Escherichia coli K-12 ortholog: b0886; Escherichia coli O157:H7 ortholog: z1230. (573 aa) |
| | c1016 | Hypothetical protein; Residues 1 to 114 of 114 are 99.12 pct identical to residues 535 to 648 of 648 from GenPept.129 : >gb|AAG55261.1|AE005269_5 (AE005269) putative ATP-binding component of a transport system [Escherichia coli O157:H7 EDL933]. (114 aa) |
| | macA | Macrolide-specific efflux protein macA precursor; Escherichia coli K-12 ortholog: b0878; Escherichia coli O157:H7 ortholog: z1115; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (380 aa) |
| | potI | Putrescine transport system permease protein potI; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (295 aa) |
| | potH | Putrescine transport system permease protein potH; Escherichia coli K-12 ortholog: b0856; Escherichia coli O157:H7 ortholog: z1083. (314 aa) |
| | potG | Putrescine transport ATP-binding protein potG; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (404 aa) |
| | modF | Putative molybdenum transport ATP-binding protein modF; Photorepair protein phrA; Escherichia coli K-12 ortholog: b0760; Escherichia coli O157:H7 ortholog: z0930. (494 aa) |
| | kdpA | Potassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (557 aa) |
| | kdpB | Potassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (682 aa) |
| | kdpC | Potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (198 aa) |
| | cyoC | Cytochrome O ubiquinol oxidase subunit III; Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity). (204 aa) |
| | cyoD | Ubiquinol oxidase chain D; Escherichia coli K-12 ortholog: b0429; Escherichia coli O157:H7 ortholog: z0532. (109 aa) |
| | c0295 | Hypothetical protein; Residues 1 to 330 of 330 are 99.39 pct identical to residues 1 to 332 of 332 from GenPept.129 : >gb|AAL67368.1|AF447814_36 (AF447814) iron-chelating periplasmic-binding protein [Escherichia coli]. (330 aa) |
| | abc | D-methionine transport ATP-binding protein metN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa) |
| | yaeE | D-methionine transport system permease protein metI; Escherichia coli K-12 ortholog: b0198; Escherichia coli O157:H7 ortholog: z0210. (217 aa) |
| | yaeC | D-methionine-binding lipoprotein metQ precursor; Escherichia coli K-12 ortholog: b0197; Escherichia coli O157:H7 ortholog: z0209; Belongs to the nlpA lipoprotein family. (270 aa) |
| | yadT | Vitamin B12 transport protein btuF precursor; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. (266 aa) |
| | fhuB | Ferrichrome uptake protein fhuB; Escherichia coli K-12 ortholog: b0153; Escherichia coli O157:H7 ortholog: z0164; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (660 aa) |
| | fhuC | Ferrichrome transport ATP-binding protein fhuC; Escherichia coli K-12 ortholog: b0151; Escherichia coli O157:H7 ortholog: z0162. (300 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Escherichia coli K-12 ortholog: b0142; Escherichia coli O157:H7 ortholog: z0153. (159 aa) |
| | kefC | Glutathione-regulated potassium-efflux system protein kefC; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (620 aa) |
| | yabF | Putative NAD(P)H oxidoreductase yabF; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily. (176 aa) |
| | csgG | Curli production assembly/transport component csgG precursor; May be involved in the biogenesis of curli organelles. Belongs to the CsgG family. (277 aa) |
| | iroC | ATP binding cassette (ABC) transporter homolog; Residues 27 to 1231 of 1245 are 80.16 pct identical to residues 1 to 1209 of 1218 from GenPept.129 : >emb|CAD05883.1| (AL627276) putative ABC transporter protein [Salmonella enterica subsp. enterica serovar Typhi]. (1245 aa) |
| | ycdO | Protein ycdO; Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component (By similarity); Belongs to the EfeM/EfeO family. (375 aa) |
| | yjgP | Hypothetical protein yjgP; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. (366 aa) |
| | ytfR | Putative ATP-binding component of a transport system; Escherichia coli K-12 ortholog: b4228; Escherichia coli O157:H7 ortholog: z5839. (500 aa) |
| | phnE | Membrane channel protein component of Pn transporter; Escherichia coli O157:H7 ortholog: z5706. (280 aa) |
| | malK | Maltose/maltodextrin transport ATP-binding protein malK; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (401 aa) |
| | malE | Maltose-binding periplasmic protein precursor; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family. (396 aa) |
| | malF | Maltose transport system permease protein malF; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (519 aa) |
| | malG | Maltose transport system permease protein malG; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (296 aa) |
| | sbp | Sulfate-binding protein precursor; Sulfate starvation-induced protein 2; Escherichia coli K-12 ortholog: b3917; Escherichia coli O157:H7 ortholog: z5462. (329 aa) |
| | rbsC | Ribose transport system permease protein rbsC; Part of the ABC transporter complex RbsABC involved in ribose import. Probably responsible for the translocation of the substrate across the membrane. (321 aa) |
| | rbsA | Ribose transport ATP-binding protein rbsA; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa) |
| | xylG | D-xylose transport ATP-binding protein xylG; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family. (525 aa) |
| | ugpB | Glycerol-3-phosphate-binding periplasmic protein precursor; sn-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system UgpACE. (438 aa) |
| | ugpA | SN-glycerol-3-phosphate transport system permease protein ugpA; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (295 aa) |
| | ugpE | SN-glycerol-3-phosphate transport system permease protein ugpE; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (281 aa) |
| | ugpC | SN-glycerol-3-phosphate transport ATP-binding protein ugpC; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (369 aa) |
| | yheR | Putative NAD(P)H oxidoreductase yheR; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. (184 aa) |
| | kefB | Glutathione-regulated potassium-efflux system protein kefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (601 aa) |
| | acrE | Acriflavine resistance protein E precursor; Protein envC; Escherichia coli K-12 ortholog: b3265; Escherichia coli O157:H7 ortholog: z4625; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (385 aa) |
| | yhbG | Probable ABC transporter ATP-binding protein yhbG; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system (By similarity). (241 aa) |
| | tolC | Outer membrane protein tolC precursor; Escherichia coli K-12 ortholog: b3035; Escherichia coli O157:H7 ortholog: z4392. (506 aa) |
| | c3717 | Hypothetical protein; Residues 3 to 342 of 356 are 29.54 pct identical to residues 2 to 350 of 372 from GenPept.129 : >gb|AAG07215.1|AE004800_4 (AE004800) conserved hypothetical protein [Pseudomonas aeruginosa]. (356 aa) |
| | c3716 | Hypothetical protein; Residues 30 to 379 of 386 are 29.17 pct identical to residues 4 to 354 of 358 from GenPept.129 : >emb|CAC92669.1| (AJ414157) putative membrane protein [Yersinia pestis]. (386 aa) |
| | c3510 | Putative ATP-binding protein of ABC transport system; Escherichia coli O157:H7 ortholog: z4271. (236 aa) |
| | c3509 | Putative ATP-binding protein of ABC transport system; Escherichia coli O157:H7 ortholog: z4270. (178 aa) |
| | proX | Glycine betaine-binding periplasmic protein precursor; Escherichia coli K-12 ortholog: b2679; Escherichia coli O157:H7 ortholog: z3981. (346 aa) |
| | proW | Glycine betaine/L-proline transport system permease protein proW; Escherichia coli K-12 ortholog: b2678; Escherichia coli O157:H7 ortholog: z3980. (354 aa) |
| | proV | Glycine betaine/L-proline transport ATP-binding protein proV; Escherichia coli K-12 ortholog: b2677; Escherichia coli O157:H7 ortholog: z3979. (400 aa) |
| | cysP | Thiosulfate-binding protein precursor; Escherichia coli K-12 ortholog: b2425; Escherichia coli O157:H7 ortholog: z3690. (338 aa) |
| | cysU | Sulfate transport system permease protein cysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (277 aa) |
| | cysW | Putative conserved protein; Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane. (291 aa) |
| | cysA | Sulfate transport ATP-binding protein cysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (365 aa) |
| | crr | PTS system, glucose-specific IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport. (169 aa) |
| | nuoA | NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (147 aa) |
| | nuoB | NADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (220 aa) |
| | nuoE | NADH dehydrogenase I chain E; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 24 kDa subunit family. (166 aa) |
| | nuoG | NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (910 aa) |
| | nuoI | NADH dehydrogenase I chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa) |
| | yjgQ | Hypothetical protein yjgQ; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. (361 aa) |
