STRINGSTRING
gntR gntR ebgR ebgR galR galR galS galS purR purR malI malI ycjW ycjW c0337 c0337 fruR fruR idnR idnR treR treR c5025 c5025 cytR cytR rbsR rbsR c4494 c4494
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gntRGluconate utilization system GNT-I transcriptional repressor; Negative regulator for the gluconate utilization system GNT- I, the gntUKR operon. (331 aa)
ebgREbg operon repressor; Escherichia coli K-12 ortholog: b3075; Escherichia coli O157:H7 ortholog: z4428. (327 aa)
galRGalactose operon repressor; Escherichia coli K-12 ortholog: b2837; Escherichia coli O157:H7 ortholog: z4155. (343 aa)
galSMgl repressor and galactose ultrainduction factor; Escherichia coli K-12 ortholog: b2151; Escherichia coli O157:H7 ortholog: z3407. (348 aa)
purRPurine nucleotide synthesis repressor; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. (341 aa)
malIMaltose regulon Regulatory protein malI; Escherichia coli K-12 ortholog: b1620; Escherichia coli O157:H7 ortholog: z2625. (342 aa)
ycjWHypothetical transcriptional regulator ycjW; Escherichia coli K-12 ortholog: b1320; Escherichia coli O157:H7 ortholog: z2461. (332 aa)
c0337Putative conserved protein; Residues 12 to 307 of 343 are 33.11 pct identical to residues 5 to 298 of 313 from MG1655 : b3438. (343 aa)
fruRFructose repressor; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. (334 aa)
idnRL-idonate Regulatory protein; Escherichia coli K-12 ortholog: b4264; Escherichia coli O157:H7 ortholog: z4806. (342 aa)
treRTrehalose operon repressor; Escherichia coli K-12 ortholog: b4241; Escherichia coli O157:H7 ortholog: z5851. (315 aa)
c5025Putative regulator; Residues 16 to 349 of 353 are 38.46 pct identical to residues 2 to 335 of 347 from GenPept.129 : >emb|CAC47885.1| (AL591793) PUTATIVE TRANSCRIPTION REGULATOR PROTEIN [Sinorhizobium meliloti]. (353 aa)
cytRTranscriptional repressor cytR; This protein negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins. Binds cytidine and adenosine as effectors (By similarity). (341 aa)
rbsRRibose operon repressor; Transcriptional repressor for the ribose rbsDACBK operon. RbsR binds to a region of perfect dyad symmetry spanning the rbs operon transcriptional start site. The affinity for the rbs operator is reduced by addition of ribose, consistent with ribose being the inducer of the operon (By similarity). (330 aa)
c4494Putative transcriptional regulator; Residues 9 to 364 of 364 are 54.03 pct identical to residues 1 to 359 of 360 from GenPept.129 : >emb|CAC89693.1| (AJ414145) LacI-family regulatory protein [Yersinia pestis]. (364 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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