STRINGSTRING
higA higA c3197 c3197 c3273 c3273 c0934 c0934 c1547 c1547 c1548 c1548 ycjW ycjW ydcN ydcN c1862 c1862 yddM yddM hipB hipB malI malI purR purR ydiL ydiL galR galR fruR fruR c0337 c0337 yiaG yiaG ybaQ ybaQ gntR gntR c4179 c4179 c5477 c5477 nlp nlp nadR nadR idnR idnR treR treR c5295 c5295 c5025 c5025 cytR cytR c4838 c4838 galS galS yfeD yfeD rbsR rbsR c4494 c4494 c3196 c3196 yfgA yfgA ebgR ebgR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
higAHypothetical protein ygjM; Antitoxin component of a type II toxin-antitoxin (TA) system. Functions as an mRNA interferase antitoxin. (138 aa)
c3197Putative repressor protein of prophage; Escherichia coli O157:H7 ortholog: z3126. (208 aa)
c3273Hypothetical protein ygjM; Escherichia coli K-12 ortholog: b3082; Escherichia coli O157:H7 ortholog: z4435. (139 aa)
c0934Hypothetical protein; Residues 114 to 307 of 308 are 47.42 pct identical to residues 5 to 198 of 198 from SwissProt.40 : >sp|P21323|YR7I_ECOLI HYPOTHETICAL 21.9 KD PROTEIN (ORFI) (RETRON EC67). (308 aa)
c1547Hypothetical protein; Residues 56 to 126 of 126 are 100.00 pct identical to residues 1 to 71 of 71 from GenPept.129 : >dbj|BAA84307.1| (AP000363) similar to C2 of bacteriophage L [Bacteriophage VT2-Sa]. (126 aa)
c1548Putative Regulatory protein CII of bacteriophage; Escherichia coli O157:H7 ortholog: z1449. (98 aa)
ycjWHypothetical transcriptional regulator ycjW; Escherichia coli K-12 ortholog: b1320; Escherichia coli O157:H7 ortholog: z2461. (332 aa)
ydcNHypothetical protein ydcN; Escherichia coli K-12 ortholog: b1434; Escherichia coli O157:H7 ortholog: z2285. (178 aa)
c1862Hypothetical protein; Residues 1 to 67 of 67 are 95.52 pct identical to residues 79 to 145 of 145 from GenPept.129 : >gb|AAC74520.1| (AE000241) orf, hypothetical protein [Escherichia coli K12]. (67 aa)
yddMHypothetical protein yddM; Escherichia coli K-12 ortholog: b1477; Escherichia coli O157:H7 ortholog: z2233; Belongs to the VapA/VapI family. (94 aa)
hipBProtein hipB; Antitoxin component of a type II type II toxin-antitoxin (TA) system. Neutralizes the toxic effect of cognate toxin HipA. Represses the hipBA operon promoter (By similarity). (94 aa)
malIMaltose regulon Regulatory protein malI; Escherichia coli K-12 ortholog: b1620; Escherichia coli O157:H7 ortholog: z2625. (342 aa)
purRPurine nucleotide synthesis repressor; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. (341 aa)
ydiLHypothetical protein ydiL; Escherichia coli K-12 ortholog: b1689; Escherichia coli O157:H7 ortholog: z2717. (127 aa)
galRGalactose operon repressor; Escherichia coli K-12 ortholog: b2837; Escherichia coli O157:H7 ortholog: z4155. (343 aa)
fruRFructose repressor; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. (334 aa)
c0337Putative conserved protein; Residues 12 to 307 of 343 are 33.11 pct identical to residues 5 to 298 of 313 from MG1655 : b3438. (343 aa)
yiaGHypothetical protein yiaG; Escherichia coli K-12 ortholog: b3555; Escherichia coli O157:H7 ortholog: z4980. (96 aa)
ybaQHypothetical protein ybaQ; Escherichia coli K-12 ortholog: b0483; Escherichia coli O157:H7 ortholog: z0602; Belongs to the VapA/VapI family. (113 aa)
gntRGluconate utilization system GNT-I transcriptional repressor; Negative regulator for the gluconate utilization system GNT- I, the gntUKR operon. (331 aa)
c4179Hypothetical protein yiaG; Escherichia coli K-12 ortholog: b3555; Escherichia coli O157:H7 ortholog: z4980. (98 aa)
c5477Hypothetical protein; Residues 16 to 85 of 94 are 38.57 pct identical to residues 6 to 75 of 84 from GenPept.129 : >gb|AAL22872.1| (AE008888) putative bacterial regulatory protein, merR family [Salmonella typhimurium LT2]. (94 aa)
nlpSugar fermentation stimulation protein B; This protein is involved in positive regulation of the metabolism of sugars. (92 aa)
nadRTranscriptional regulator nadR; Escherichia coli K-12 ortholog: b4390; Escherichia coli O157:H7 ortholog: z5991. (417 aa)
idnRL-idonate Regulatory protein; Escherichia coli K-12 ortholog: b4264; Escherichia coli O157:H7 ortholog: z4806. (342 aa)
treRTrehalose operon repressor; Escherichia coli K-12 ortholog: b4241; Escherichia coli O157:H7 ortholog: z5851. (315 aa)
c5295Hypothetical protein. (163 aa)
c5025Putative regulator; Residues 16 to 349 of 353 are 38.46 pct identical to residues 2 to 335 of 347 from GenPept.129 : >emb|CAC47885.1| (AL591793) PUTATIVE TRANSCRIPTION REGULATOR PROTEIN [Sinorhizobium meliloti]. (353 aa)
cytRTranscriptional repressor cytR; This protein negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins. Binds cytidine and adenosine as effectors (By similarity). (341 aa)
c4838Hypothetical protein; Residues 13 to 94 of 96 are 87.80 pct identical to residues 1 to 82 of 84 from GenPept.129 : >gb|AAL22872.1| (AE008888) putative bacterial regulatory protein, merR family [Salmonella typhimurium LT2]. (96 aa)
galSMgl repressor and galactose ultrainduction factor; Escherichia coli K-12 ortholog: b2151; Escherichia coli O157:H7 ortholog: z3407. (348 aa)
yfeDHypothetical protein yfeD; Escherichia coli K-12 ortholog: b2399; Escherichia coli O157:H7 ortholog: z3663. (130 aa)
rbsRRibose operon repressor; Transcriptional repressor for the ribose rbsDACBK operon. RbsR binds to a region of perfect dyad symmetry spanning the rbs operon transcriptional start site. The affinity for the rbs operator is reduced by addition of ribose, consistent with ribose being the inducer of the operon (By similarity). (330 aa)
c4494Putative transcriptional regulator; Residues 9 to 364 of 364 are 54.03 pct identical to residues 1 to 359 of 360 from GenPept.129 : >emb|CAC89693.1| (AJ414145) LacI-family regulatory protein [Yersinia pestis]. (364 aa)
c3196Hypothetical protein; Residues 1 to 65 of 66 are 53.84 pct identical to residues 1 to 65 of 75 from GenPept.129 : >dbj|BAB36188.1| (AP002559) putative cell division control protein [Escherichia coli O157:H7]. (66 aa)
yfgAHypothetical protein yfgA; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. (335 aa)
ebgREbg operon repressor; Escherichia coli K-12 ortholog: b3075; Escherichia coli O157:H7 ortholog: z4428. (327 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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