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ygcE ygcE nagC nagC ycfX ycfX mlc mlc ydhH ydhH ybeW ybeW c0503 c0503 ftsA ftsA araB araB dnaK dnaK yeaZ yeaZ yegD yegD ackA ackA glk glk c2976 c2976 eutJ eutJ ppx ppx hscA hscA yphH yphH nanK2 nanK2 ygjD ygjD tdcD-2 tdcD-2 nanK1 nanK1 mreB mreB yheK yheK yrfD yrfD c4280 c4280 xylB xylB lyxK lyxK c4482 c4482 c4526 c4526 tdcD tdcD gppA gppA rhaB rhaB glpK glpK yjcT yjcT yjiL yjiL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ygcEHypothetical sugar kinase ygcE; Escherichia coli K-12 ortholog: b2776; Escherichia coli O157:H7 ortholog: z4087. (492 aa)
nagCN-acetylglucosamine repressor; Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon. (406 aa)
ycfXHypothetical protein ycfX; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. (303 aa)
mlcMlc protein; Making large colonies protein; Escherichia coli K-12 ortholog: b1594; Escherichia coli O157:H7 ortholog: z2587. (406 aa)
ydhHHypothetical protein ydhH; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (369 aa)
ybeWChaperone protein hscC; Hsc62; Escherichia coli K-12 ortholog: b0650; Escherichia coli O157:H7 ortholog: z0800; Belongs to the heat shock protein 70 family. (566 aa)
c0503Hypothetical protein yajF; Escherichia coli K-12 ortholog: b0394; Escherichia coli O157:H7 ortholog: z0493. (348 aa)
ftsACell division protein ftsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. (420 aa)
araBL-ribulokinase; Escherichia coli K-12 ortholog: b0063; Escherichia coli O157:H7 ortholog: z0072. (566 aa)
dnaKChaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (638 aa)
yeaZHypothetical protease yeaZ; Escherichia coli K-12 ortholog: b1807; Escherichia coli O157:H7 ortholog: z2850. (231 aa)
yegDHypothetical chaperone protein yegD; Escherichia coli K-12 ortholog: b2069; Escherichia coli O157:H7 ortholog: z3238. (471 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
glkGlucokinase; Not highly important in E.coli as glucose is transported into the cell by the PTS system already as glucose 6-phosphate. (321 aa)
c2976Ethanolamine utilization protein eutA; Escherichia coli K-12 ortholog: b2451; Escherichia coli O157:H7 ortholog: z3707. (467 aa)
eutJEthanolamine utilization protein eutJ; Escherichia coli K-12 ortholog: b2454; Escherichia coli O157:H7 ortholog: z3710. (278 aa)
ppxExopolyphosphatase; Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain. (513 aa)
hscAChaperone protein hscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. (634 aa)
yphHHypothetical protein yphH; Escherichia coli K-12 ortholog: b2550; Escherichia coli O157:H7 ortholog: z3826. (399 aa)
nanK2Hypothetical protein yhcI; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. (291 aa)
ygjDProbable O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (337 aa)
tdcD-2Putative conserved protein; Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP. (50 aa)
nanK1Hypothetical protein yhcI; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. (302 aa)
mreBRod shape-determining protein mreB; Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature. (372 aa)
yheKProbable general secretion pathway protein L; Escherichia coli K-12 ortholog: b3333; Escherichia coli O157:H7 ortholog: z2633. (388 aa)
yrfDHypothetical protein yrfD; Escherichia coli K-12 ortholog: b3395; Escherichia coli O157:H7 ortholog: z4749. (268 aa)
c4280Putative xylulose kinase; Escherichia coli O157:H7 ortholog: z4878. (482 aa)
xylBXylulose kinase; Escherichia coli K-12 ortholog: b3564; Escherichia coli O157:H7 ortholog: z4989. (484 aa)
lyxKCryptic L-xylulose kinase; Escherichia coli K-12 ortholog: b3580; Belongs to the FGGY kinase family. (498 aa)
c4482Hypothetical protein yajF; Escherichia coli K-12 ortholog: b0394; Escherichia coli O157:H7 ortholog: z0493. (321 aa)
c4526Ethanolamine utilization protein eutJ; Escherichia coli K-12 ortholog: b2454; Escherichia coli O157:H7 ortholog: z3710. (252 aa)
tdcDPropionate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (406 aa)
gppAGuanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities. (497 aa)
rhaBRhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. (489 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (537 aa)
yjcTD-allose kinase; Catalyzes the phosphorylation of D-allose to D-allose 6- phosphate. (309 aa)
yjiLHypothetical protein yjiL; Escherichia coli K-12 ortholog: b4334; Escherichia coli O157:H7 ortholog: z5936. (257 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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