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plsB plsB cdh cdh gpsA gpsA ygiH ygiH psd psd dgkA dgkA plsC plsC yegS yegS pgsA pgsA cls cls plsX plsX ymdC ymdC ybhO ybhO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
plsBGlycerol-3-phosphate acyltransferase; Escherichia coli K-12 ortholog: b4041; Escherichia coli O157:H7 ortholog: z5640; Belongs to the GPAT/DAPAT family. (827 aa)
cdhCDP-diacylglycerol pyrophosphatase; Escherichia coli K-12 ortholog: b3918; Escherichia coli O157:H7 ortholog: z5463. (315 aa)
gpsAGlycerol-3-phosphate dehydrogenase (NAD(P)+); Escherichia coli K-12 ortholog: b3608; Escherichia coli O157:H7 ortholog: z5035; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (339 aa)
ygiHHypothetical protein ygiH; Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl- PO(4); Belongs to the PlsY family. (205 aa)
psdPhosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (322 aa)
dgkADiacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (122 aa)
plsC1-acyl-sn-glycerol-3-phosphate acyltransferase; Escherichia coli K-12 ortholog: b3018; Escherichia coli O157:H7 ortholog: z4372; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (245 aa)
yegSHypothetical protein yegS; Probably phosphorylates lipids; the in vivo substrate is unknown. (299 aa)
pgsACDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (182 aa)
clsCardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (486 aa)
plsXFatty acid/phospholipid synthesis protein plsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (356 aa)
ymdCHypothetical protein ymdC; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE); Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsC sub-subfamily. (493 aa)
ybhOHypothetical protein ybhO; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (413 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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