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frdA frdA lpdA lpdA sdhA sdhA yeiT yeiT glpB glpB nadB nadB ygfK ygfK udhA udhA c5021 c5021 c5035 c5035 c5299 c5299
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
frdAFumarate reductase flavoprotein subunit; Escherichia coli K-12 ortholog: b4154; Escherichia coli O157:H7 ortholog: z5762. (602 aa)
lpdADihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (495 aa)
sdhASuccinate dehydrogenase flavoprotein subunit; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (592 aa)
yeiTHypothetical oxidoreductase yeiT; Escherichia coli K-12 ortholog: b2146; Escherichia coli O157:H7 ortholog: z3401. (412 aa)
glpBAnaerobic glycerol-3-phosphate dehydrogenase subunit B; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor; Belongs to the anaerobic G-3-P dehydrogenase subunit B family. (443 aa)
nadBL-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (540 aa)
ygfKHypothetical protein ygfK; Escherichia coli K-12 ortholog: b2878; Escherichia coli O157:H7 ortholog: z4217. (1032 aa)
udhASoluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation. (466 aa)
c5021Putative oxidoreductase; Residues 70 to 648 of 721 are 36.66 pct identical to residues 6 to 596 of 664 from GenPept.129 : >gb|AAD35512.1|AE001721_11 (AE001721) oxidoreductase, putative [Thermotoga maritima]. (721 aa)
c5035Putative 2-oxoglutarate dehydrogenase; Residues 1 to 468 of 472 are 49.04 pct identical to residues 1 to 470 of 474 from SwissProt.40 : >sp|P52992|DLDH_ALCEU DIHYDROLIPOAMIDE DEHYDROGENASE (E3 COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX). (472 aa)
c5299Putative oxidoreductase; Residues 29 to 688 of 690 are 35.69 pct identical to residues 5 to 663 of 664 from GenPept.129 : >gb|AAD35512.1|AE001721_11 (AE001721) oxidoreductase, putative [Thermotoga maritima]. (690 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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