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fimH fimH ompC ompC nlpB nlpB chuA chuA yibK yibK sodA sodA yjaA yjaA lysC lysC esiB esiB polB polB tsx tsx fepA fepA ybiL ybiL ompX ompX ompF ompF ompA ompA wrbA wrbA yncE yncE slyB slyB osmE osmE cirA cirA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fimHFimH protein precursor; Escherichia coli K-12 ortholog: b4320; Escherichia coli O157:H7 ortholog: z5918. (303 aa)
ompCOuter membrane protein C precursor; Forms pores that allow passive diffusion of small molecules across the outer membrane, including some antibiotics. Variation of the residues in the constriction zone modifies the transverse electric field in the zone, altering antibiotic resistance. Belongs to the Gram-negative porin family. (375 aa)
nlpBLipoprotein-34 precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (345 aa)
chuAOuter membrane heme/hemoglobin receptor; Escherichia coli O157:H7 ortholog: z4911. (648 aa)
yibKHypothetical tRNA/rRNA methyltransferase yibK; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (157 aa)
sodASuperoxide dismutase (Mn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (208 aa)
yjaAHypothetical protein yjaA; Escherichia coli K-12 ortholog: b4011. (139 aa)
lysCLysine-sensitive aspartokinase III; Escherichia coli K-12 ortholog: b4024; Escherichia coli O157:H7 ortholog: z5622; Belongs to the aspartokinase family. (449 aa)
esiBPutative conserved protein; Upon host (human neutrophil) infection interferes with productive FCAR signaling, inhibiting secreted IgA (SIgA) effector functions and probably avoiding neutrophil activation. Inhibits the SIgA-mediated oxidative burst by neutrophils, decreases generation of ROS (reactive oxygen species) by neutrophils and reduces chemotaxis by neutrophils, all of which are SIgA effector functions used to stimulate the immune response. Does not block SIgA-binding to its receptor (FCAR) on neutrophils, but it decreases SIgA-stimulated phosphorylation of cytoplasmic proteins, [...] (490 aa)
polBDNA polymerase II; Escherichia coli K-12 ortholog: b0060; Escherichia coli O157:H7 ortholog: z0068. (783 aa)
tsxNucleoside-specific channel-forming protein tsx precursor; Escherichia coli K-12 ortholog: b0411; Escherichia coli O157:H7 ortholog: z0512. (310 aa)
fepAFerrienterobactin receptor precursor; Enterobactin outer-membrane receptor; Escherichia coli K-12 ortholog: b0584; Escherichia coli O157:H7 ortholog: z0724. (746 aa)
ybiLProbable tonB-dependent receptor ybiL precursor; Involved in the active transport across the outer membrane of iron complexed with catecholate siderophores such as dihydroxybenzoylserine and dihydroxybenzoate. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB. Can also transport catechol-substituted cephalosporins. Receptor for microcins M, H47 and E492 (By similarity). (760 aa)
ompXOuter membrane protein X precursor; Escherichia coli K-12 ortholog: b0814; Escherichia coli O157:H7 ortholog: z1036. (173 aa)
ompFOuter membrane protein F precursor; Porin ompF; Escherichia coli K-12 ortholog: b0929; Escherichia coli O157:H7 ortholog: z1276; Belongs to the Gram-negative porin family. (362 aa)
ompAOuter membrane protein II*; Escherichia coli K-12 ortholog: b0957; Escherichia coli O157:H7 ortholog: z1307; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (379 aa)
wrbAFlavoprotein wrbA; Trp repressor binding protein; Escherichia coli K-12 ortholog: b1004; Escherichia coli O157:H7 ortholog: z1423. (198 aa)
yncEHypothetical protein yncE precursor; Escherichia coli K-12 ortholog: b1452; Escherichia coli O157:H7 ortholog: z2267. (353 aa)
slyBOuter membrane lipoprotein slyB precursor; Escherichia coli K-12 ortholog: b1641; Escherichia coli O157:H7 ortholog: z2655. (155 aa)
osmEOsmotically inducible lipoprotein E precursor; Activator of ntr-like gene; Escherichia coli K-12 ortholog: b1739; Escherichia coli O157:H7 ortholog: z2769. (112 aa)
cirAColicin I receptor precursor; Escherichia coli K-12 ortholog: b2155; Escherichia coli O157:H7 ortholog: z3411. (690 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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