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dsbA dsbA rhaB rhaB lysC lysC yfiO yfiO yfgL yfgL ompC ompC rlpB rlpB ompA ompA ompT ompT phoE phoE hlpA hlpA yaeT yaeT imp imp surA surA upaG upaG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dsbAThiol:disulfide interchange protein dsbA precursor; Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. It is required for pilus biogenesis (By similarity). Belongs to the thioredoxin family. DsbA subfamily. (208 aa)
rhaBRhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. (489 aa)
lysCLysine-sensitive aspartokinase III; Escherichia coli K-12 ortholog: b4024; Escherichia coli O157:H7 ortholog: z5622; Belongs to the aspartokinase family. (449 aa)
yfiOHypothetical lipoprotein yfiO precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. (245 aa)
yfgLHypothetical protein yfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (392 aa)
ompCOuter membrane protein C precursor; Forms pores that allow passive diffusion of small molecules across the outer membrane, including some antibiotics. Variation of the residues in the constriction zone modifies the transverse electric field in the zone, altering antibiotic resistance. Belongs to the Gram-negative porin family. (375 aa)
rlpBRare lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. (193 aa)
ompAOuter membrane protein II*; Escherichia coli K-12 ortholog: b0957; Escherichia coli O157:H7 ortholog: z1307; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (379 aa)
ompTProtease VII precursor; Escherichia coli K-12 ortholog: b0565; Escherichia coli O157:H7 ortholog: z1931. (317 aa)
phoEOuter membrane pore protein E precursor; Escherichia coli K-12 ortholog: b0241; Escherichia coli O157:H7 ortholog: z0302; Belongs to the Gram-negative porin family. (353 aa)
hlpAHistone-like protein HLP-1 precursor; Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm. (161 aa)
yaeTUnknown protein from 2D-page spots M62/M63/O3/O9/T35 precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. (810 aa)
impOrganic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Belongs to the LptD family. (784 aa)
surASurvival protein surA precursor; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (428 aa)
upaGPutative adhesin; Mediates aggregation, biofilm formation and adhesion to a range of extracellular matrix (ECM) proteins, such as fibronectin, fibrinogen, laminin and collagen types I, II, III, and V. Mediates adhesion to human T24 bladder epithelial cells. (1778 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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