STRINGSTRING
fimB fimB sugE sugE papA papA papK papK cmr cmr dacA dacA ftsI ftsI araC araC fimI fimI fimC fimC fimE fimE fimF fimF fimH fimH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fimBType 1 fimbriae Regulatory protein fimB; Escherichia coli K-12 ortholog: b4312; Escherichia coli O157:H7 ortholog: z5910. (200 aa)
sugESugE protein; Guanidinium ion exporter. Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons. Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Gdx/SugE subfamily. (155 aa)
papAPapA protein; Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs; Belongs to the fimbrial protein family. (199 aa)
papKPapK protein; Adapter that links the pilus rod to the base of the tip fibrillum. Regulates the length of the tip fibrillum and joins it to the pilus rod. Pili are polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, and enable bacteria to colonize the epithelium of specific host organs (By similarity). (179 aa)
cmrMultidrug translocase mdfA; Efflux pump driven by the proton motive force. Confers resistance to a broad spectrum of chemically unrelated drugs (By similarity). (420 aa)
dacAPenicillin-binding protein 5 precursor; Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Belongs to the peptidase S11 family. (403 aa)
ftsIPeptidoglycan synthetase ftsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (588 aa)
araCArabinose operon Regulatory protein; Escherichia coli K-12 ortholog: b0064; Escherichia coli O157:H7 ortholog: z0073. (281 aa)
fimIFimbrin-like protein fimI precursor; Escherichia coli K-12 ortholog: b4315; Escherichia coli O157:H7 ortholog: z5913. (179 aa)
fimCChaperone protein fimC precursor; Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH (By similarity); Belongs to the periplasmic pilus chaperone family. (241 aa)
fimEType 1 fimbriae Regulatory protein fimE; FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off (By similarity). (198 aa)
fimFFimF protein precursor; Escherichia coli K-12 ortholog: b4318; Escherichia coli O157:H7 ortholog: z5916. (177 aa)
fimHFimH protein precursor; Escherichia coli K-12 ortholog: b4320; Escherichia coli O157:H7 ortholog: z5918. (303 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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