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trxB trxB c1175 c1175 ynfE ynfE ynfF ynfF malY malY sufS sufS selD selD metG metG cysN cysN cysD cysD c3407 c3407 ygfK ygfK ygfM ygfM c3459 c3459 metC metC selA selA metE metE metB metB metH metH
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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trxBThioredoxin reductase; Escherichia coli K-12 ortholog: b0888; Escherichia coli O157:H7 ortholog: z1232. (361 aa)
c1175Putative aminotransferase; Residues 2 to 387 of 388 are 34.62 pct identical to residues 1 to 377 of 384 from GenPept.129 : >gb|AAK80912.1|AE007794_4 (AE007794) PLP-dependent aminotransferase, [Clostridium acetobutylicum]. (388 aa)
ynfEPutative dimethyl sulfoxide reductase chain ynfE precursor; Escherichia coli K-12 ortholog: b1587; Escherichia coli O157:H7 ortholog: z2575; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (808 aa)
ynfFProbable dimethyl sulfoxide reductase chain ynfF precursor; Escherichia coli K-12 ortholog: b1588; Escherichia coli O157:H7 ortholog: z2576; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (808 aa)
malYMalY protein; Escherichia coli K-12 ortholog: b1622; Escherichia coli O157:H7 ortholog: z2627; bifunctional; Cystathionine beta-lyase; Maltose regulon modulator. (390 aa)
sufSSelenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo. (406 aa)
selDSelenide,water dikinase; Synthesizes selenophosphate from selenide and ATP. (349 aa)
metGMethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (680 aa)
cysNSulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (475 aa)
cysDSulfate adenylyltransferase subunit 2; Escherichia coli K-12 ortholog: b2752; Escherichia coli O157:H7 ortholog: z4060. (302 aa)
c3407Beta-cystathionase; Residues 1 to 336 of 391 are 99.70 pct identical to residues 1 to 336 of 336 from GenPept.129 : >gb|AAC61731.1| (AF081286) beta-cystathionase [Escherichia coli]. (391 aa)
ygfKHypothetical protein ygfK; Escherichia coli K-12 ortholog: b2878; Escherichia coli O157:H7 ortholog: z4217. (1032 aa)
ygfMHypothetical protein ygfM; Escherichia coli K-12 ortholog: b2880; Escherichia coli O157:H7 ortholog: z4219. (259 aa)
c3459Possible hypoxanthine oxidase xdhD; Escherichia coli K-12 ortholog: b2881; Escherichia coli O157:H7 ortholog: z4220. (956 aa)
metCCystathionine beta-lyase; Escherichia coli K-12 ortholog: b3008; Escherichia coli O157:H7 ortholog: z4361. (440 aa)
selAL-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. (463 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (753 aa)
metBCystathionine gamma-synthase; Escherichia coli K-12 ortholog: b3939; Escherichia coli O157:H7 ortholog: z5494. (424 aa)
metH5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1227 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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