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cdsA cdsA pgpA pgpA ybhO ybhO ymdC ymdC cls cls pgpB pgpB ynbB ynbB pgsA pgsA glpQ glpQ glpA glpA glpB glpB glpC glpC eutC eutC eutB eutB c2976 c2976 yfhB yfhB pssA pssA aas aas c3696 c3696 plsC plsC ygiH ygiH glpD glpD ugpQ ugpQ gpsA gpsA pldA pldA pldB pldB cdh cdh plsB plsB dgkA dgkA psd psd
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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cdsAPhosphatidate cytidylyltransferase; Escherichia coli K-12 ortholog: b0175; Escherichia coli O157:H7 ortholog: z0186; Belongs to the CDS family. (285 aa)
pgpAPhosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (172 aa)
ybhOHypothetical protein ybhO; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (413 aa)
ymdCHypothetical protein ymdC; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE); Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsC sub-subfamily. (493 aa)
clsCardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (486 aa)
pgpBEscherichia coli K-12 ortholog: b1278; Escherichia coli O157:H7 ortholog: z2529. (254 aa)
ynbBHypothetical protein ynbB; Escherichia coli K-12 ortholog: b1409; Escherichia coli O157:H7 ortholog: z2318. (298 aa)
pgsACDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (182 aa)
glpQGlycerophosphoryl diester phosphodiesterase, periplasmic precursor; Escherichia coli K-12 ortholog: b2239; Escherichia coli O157:H7 ortholog: z3497. (358 aa)
glpAAnaerobic glycerol-3-phosphate dehydrogenase subunit A; Escherichia coli K-12 ortholog: b2241; Escherichia coli O157:H7 ortholog: z3499; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (542 aa)
glpBAnaerobic glycerol-3-phosphate dehydrogenase subunit B; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor; Belongs to the anaerobic G-3-P dehydrogenase subunit B family. (443 aa)
glpCAnaerobic glycerol-3-phosphate dehydrogenase subunit C; G-3-P dehydrogenase; Escherichia coli K-12 ortholog: b2243; Escherichia coli O157:H7 ortholog: z3501. (421 aa)
eutCEthanolamine ammonia-lyase light chain; Escherichia coli K-12 ortholog: b2440; Escherichia coli O157:H7 ortholog: z3705; Belongs to the EutC family. (295 aa)
eutBEthanolamine ammonia-lyase heavy chain; Escherichia coli K-12 ortholog: b2441; Escherichia coli O157:H7 ortholog: z3706. (453 aa)
c2976Ethanolamine utilization protein eutA; Escherichia coli K-12 ortholog: b2451; Escherichia coli O157:H7 ortholog: z3707. (467 aa)
yfhBHypothetical protein yfhB; Escherichia coli K-12 ortholog: b2560; Escherichia coli O157:H7 ortholog: z3840. (204 aa)
pssACDP-diacylglycerol--serine O-phosphatidyltransferase; Escherichia coli K-12 ortholog: b2585; Escherichia coli O157:H7 ortholog: z3870. (452 aa)
aasAAS bifunctional protein; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1. (719 aa)
c3696Putative glycerol-3-phosphate cytidyltransferase; Residues 5 to 131 of 135 are 49.60 pct identical to residues 1 to 126 of 129 from SwissProt.40 : >sp|P27623|TAGD_BACSU Glycerol-3-phosphate cytidylyltransferase (GCT) (CDP-glycerol pyrophosphorylase) (Teichoic acid biosynthesis protein D). (135 aa)
plsC1-acyl-sn-glycerol-3-phosphate acyltransferase; Escherichia coli K-12 ortholog: b3018; Escherichia coli O157:H7 ortholog: z4372; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (245 aa)
ygiHHypothetical protein ygiH; Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl- PO(4); Belongs to the PlsY family. (205 aa)
glpDAerobic glycerol-3-phosphate dehydrogenase; Escherichia coli K-12 ortholog: b3426; Escherichia coli O157:H7 ortholog: z4786; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (506 aa)
ugpQGlycerophosphoryl diester phosphodiesterase; Escherichia coli K-12 ortholog: b3449; Escherichia coli O157:H7 ortholog: z4817. (247 aa)
gpsAGlycerol-3-phosphate dehydrogenase (NAD(P)+); Escherichia coli K-12 ortholog: b3608; Escherichia coli O157:H7 ortholog: z5035; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (339 aa)
pldAPhospholipase A1 precursor; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. (289 aa)
pldBLysophospholipase L2; Escherichia coli K-12 ortholog: b3825; Escherichia coli O157:H7 ortholog: z5346. (340 aa)
cdhCDP-diacylglycerol pyrophosphatase; Escherichia coli K-12 ortholog: b3918; Escherichia coli O157:H7 ortholog: z5463. (315 aa)
plsBGlycerol-3-phosphate acyltransferase; Escherichia coli K-12 ortholog: b4041; Escherichia coli O157:H7 ortholog: z5640; Belongs to the GPAT/DAPAT family. (827 aa)
dgkADiacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (122 aa)
psdPhosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (322 aa)
Your Current Organism:
Escherichia coli CFT073
NCBI taxonomy Id: 199310
Other names: E. coli CFT073, Escherichia coli str. CFT073, Escherichia coli strain CFT073
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