STRINGSTRING
mtcA1 mtcA1 nasF_1 nasF_1 ARK28588.1 ARK28588.1 mdlA mdlA ttdB ttdB ectC ectC pheA pheA nasF_2 nasF_2 mtnB mtnB uxaA uxaA nanA_2 nanA_2 hgdB hgdB fldC fldC fldB fldB fumC fumC mqnA mqnA trpB trpB trpA trpA dapA_1 dapA_1 can can queD queD citB_1 citB_1 hutU_1 hutU_1 hutU_2 hutU_2 dapA_2 dapA_2 aroD aroD iolE iolE hemB hemB hemD hemD leuD1 leuD1 leuC leuC ilvD ilvD eno eno hisB hisB ARK32287.1 ARK32287.1 citB_3 citB_3 ARK32667.1 ARK32667.1 fabZ fabZ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mtcA1Beta-carbonic anhydrase 1. (191 aa)
nasF_1NarK family nitrate/nitrite MFS transporter NarK2; Frameshift. (493 aa)
ARK28588.1uroporphyrinogen-III synthase. (268 aa)
mdlAMandelate racemase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (373 aa)
ttdBL(+)-tartrate dehydratase subunit beta; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (512 aa)
ectCL-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (130 aa)
pheAPrephenate dehydratase. (277 aa)
nasF_2Uroporphyrinogen-III C-methyltransferase. (489 aa)
mtnBMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (207 aa)
uxaAAltronate dehydratase. (498 aa)
nanA_2N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. (288 aa)
hgdB(R)-2-hydroxyglutaryl-CoA dehydratase subunit beta. (199 aa)
fldCR-phenyllactate dehydratase beta subunit. (185 aa)
fldBR-phenyllactate dehydratase subunit alpha precursor. (433 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa)
mqnAChorismate dehydratase; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (283 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (400 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa)
dapA_14-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)
canCarbonic anhydrase 2. (185 aa)
queD6-carboxy-5,6,7,8-tetrahydropterin synthase. (140 aa)
citB_1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (904 aa)
hutU_1Urocanate hydratase. (61 aa)
hutU_2Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (508 aa)
dapA_2Ribonuclease J 2; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (286 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (282 aa)
iolEInosose dehydratase. (269 aa)
hemBDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (327 aa)
hemDUroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (256 aa)
leuD13-isopropylmalate dehydratase small subunit 1; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (190 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (555 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa)
hisBImidazoleglycerol-phosphate dehydratase. (196 aa)
ARK32287.1Proline racemase; Belongs to the proline racemase family. (323 aa)
citB_3Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (887 aa)
ARK32667.1Polyketide cyclase / dehydrase and lipid transport. (152 aa)
fabZ3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (142 aa)
Your Current Organism:
Bacillus krulwichiae
NCBI taxonomy Id: 199441
Other names: B. krulwichiae, Bacillus krulwichiae Yumoto et al. 2003, Bacillus krulwichii, IAM 15000, JCM 11691, NBRC 102362, NCIMB 13904, strain AM31D
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.