(20 nodes) Positive regulation of ERK1 and ERK2 cascade network (Anopheles epiroticus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182P1D0	Uncharacterized protein. (1655 aa)
	A0A182P2P9	Uncharacterized protein. (640 aa)
	A0A182P466	USP domain-containing protein; Belongs to the peptidase C19 family. (1373 aa)
	A0A182P8Q3	Uncharacterized protein. (731 aa)
	A0A182PD29	4Fe-4S ferredoxin-type domain-containing protein. (879 aa)
	A0A182PDQ2	Uncharacterized protein; Belongs to the cyclic nucleotide phosphodiesterase family. (1077 aa)
	A0A182PEE3	Uncharacterized protein. (162 aa)
	A0A182PFR1	Uncharacterized protein. (1834 aa)
	A0A182PGD0	SAM domain-containing protein. (111 aa)
	A0A182PH06	Uncharacterized protein. (1203 aa)
	A0A182PJZ6	SH2 domain-containing protein. (107 aa)
	A0A182PJZ7	Uncharacterized protein. (1158 aa)
	A0A182PMR7	Uncharacterized protein. (383 aa)
	A0A182PP65	DHR-1 domain-containing protein; Belongs to the DOCK family. (920 aa)
	A0A182PP68	DHR-2 domain-containing protein; Belongs to the DOCK family. (943 aa)
	A0A182PS97	Uncharacterized protein. (182 aa)
	A0A182PT06	Uncharacterized protein. (928 aa)
	A0A182PTW4	Uncharacterized protein. (637 aa)
	A0A182PUX5	Ig-like domain-containing protein. (156 aa)
	A0A182PWA5	Uncharacterized protein. (303 aa)

Your Current Organism:

Anopheles epiroticus

NCBI taxonomy Id: 199890
Other names: A. epiroticus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182P1D0	A0A182P2P9	Uncharacterized protein.	Uncharacterized protein.	0.632
A0A182P1D0	A0A182PD29	Uncharacterized protein.	4Fe-4S ferredoxin-type domain-containing protein.	0.857
A0A182P1D0	A0A182PEE3	Uncharacterized protein.	Uncharacterized protein.	0.625
A0A182P1D0	A0A182PFR1	Uncharacterized protein.	Uncharacterized protein.	0.549
A0A182P1D0	A0A182PJZ6	Uncharacterized protein.	SH2 domain-containing protein.	0.650
A0A182P1D0	A0A182PJZ7	Uncharacterized protein.	Uncharacterized protein.	0.650
A0A182P1D0	A0A182PS97	Uncharacterized protein.	Uncharacterized protein.	0.889
A0A182P1D0	A0A182PTW4	Uncharacterized protein.	Uncharacterized protein.	0.590
A0A182P2P9	A0A182P1D0	Uncharacterized protein.	Uncharacterized protein.	0.632
A0A182P2P9	A0A182PD29	Uncharacterized protein.	4Fe-4S ferredoxin-type domain-containing protein.	0.570
A0A182P2P9	A0A182PH06	Uncharacterized protein.	Uncharacterized protein.	0.632
A0A182P2P9	A0A182PJZ6	Uncharacterized protein.	SH2 domain-containing protein.	0.709
A0A182P2P9	A0A182PJZ7	Uncharacterized protein.	Uncharacterized protein.	0.709
A0A182P2P9	A0A182PMR7	Uncharacterized protein.	Uncharacterized protein.	0.632
A0A182P2P9	A0A182PS97	Uncharacterized protein.	Uncharacterized protein.	0.854
A0A182P2P9	A0A182PT06	Uncharacterized protein.	Uncharacterized protein.	0.560
A0A182P8Q3	A0A182PEE3	Uncharacterized protein.	Uncharacterized protein.	0.593
A0A182P8Q3	A0A182PFR1	Uncharacterized protein.	Uncharacterized protein.	0.581
A0A182PD29	A0A182P1D0	4Fe-4S ferredoxin-type domain-containing protein.	Uncharacterized protein.	0.857
A0A182PD29	A0A182P2P9	4Fe-4S ferredoxin-type domain-containing protein.	Uncharacterized protein.	0.570