(55 nodes) Biosynthesis of unsaturated fatty acids network (Anopheles epiroticus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	A0A182PUE7	Hydrolase_4 domain-containing protein. (356 aa)
	A0A182PT22	Elongation of very long chain fatty acids protein. (546 aa)
	A0A182PSJ2	FA_desaturase domain-containing protein; Belongs to the fatty acid desaturase type 1 family. (355 aa)
	A0A182PS55	FA_desaturase domain-containing protein; Belongs to the fatty acid desaturase type 1 family. (302 aa)
	A0A182PS54	Uncharacterized protein. (153 aa)
	A0A182PS28	Uncharacterized protein. (564 aa)
	A0A182PS01	Elongation of very long chain fatty acids protein. (217 aa)
	A0A182PQT3	FA_desaturase domain-containing protein; Belongs to the fatty acid desaturase type 1 family. (252 aa)
	A0A182PQR9	Uncharacterized protein. (84 aa)
	A0A182PJF8	Uncharacterized protein. (724 aa)
	A0A182PKF1	C2H2-type domain-containing protein. (447 aa)
	A0A182PLE3	Elongation of very long chain fatty acids protein. (358 aa)
	A0A182PLE4	Elongation of very long chain fatty acids protein. (331 aa)
	A0A182PLF1	SCP2 domain-containing protein. (696 aa)
	A0A182PLT3	Uncharacterized protein. (369 aa)
	A0A182PM20	S5A_REDUCTASE domain-containing protein. (299 aa)
	A0A182PM31	Elongation of very long chain fatty acids protein. (263 aa)
	A0A182PM32	Elongation of very long chain fatty acids protein. (289 aa)
	A0A182PM33	Elongation of very long chain fatty acids protein. (240 aa)
	A0A182PCI2	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (463 aa)
	A0A182PCZ0	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (763 aa)
	A0A182PHX0	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (329 aa)
	A0A182PR35	Elongation of very long chain fatty acids protein. (203 aa)
	A0A182PQX8	Uncharacterized protein. (1502 aa)
	A0A182PQR8	Elongation of very long chain fatty acids protein. (275 aa)
	A0A182PPU1	Uncharacterized protein. (453 aa)
	A0A182PPE8	Uncharacterized protein. (434 aa)
	A0A182PNM3	Uncharacterized protein. (225 aa)
	A0A182PNM2	SCP2 domain-containing protein. (105 aa)
	A0A182PMB9	Uncharacterized protein. (779 aa)
	A0A182P4K2	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (325 aa)
	A0A182PI81	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (695 aa)
	A0A182PJ65	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (544 aa)
	A0A182P4T4	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (694 aa)
	A0A182P4Z2	Elongation of very long chain fatty acids protein. (319 aa)
	A0A182P528	Elongation of very long chain fatty acids protein. (313 aa)
	A0A182P769	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (233 aa)
	A0A182P7S4	Cytochrome b5 heme-binding domain-containing protein. (453 aa)
	A0A182PQT4	Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (293 aa)
	A0A240PPN7	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (240 aa)
	A0A182PWY9	Uncharacterized protein. (504 aa)
	A0A182PWS9	Elongation of very long chain fatty acids protein. (183 aa)
	A0A182PW58	Elongation of very long chain fatty acids protein. (92 aa)
	A0A182PW57	Elongation of very long chain fatty acids protein. (300 aa)
	A0A182P2Z9	SCP2 domain-containing protein. (111 aa)
	A0A182P229	Elongation of very long chain fatty acids protein. (313 aa)
	A0A182P0P5	Elongation of very long chain fatty acids protein. (433 aa)
	A0A182PVT9	AB hydrolase-1 domain-containing protein. (306 aa)
	A0A182P7S7	Uncharacterized protein. (511 aa)
	A0A182P925	Elongation of very long chain fatty acids protein. (326 aa)
	A0A182PAC5	Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (799 aa)
	A0A182PAC8	Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (412 aa)
	A0A182PAC9	FA_desaturase domain-containing protein; Belongs to the fatty acid desaturase type 1 family. (400 aa)
	A0A182PAD9	Uncharacterized protein. (1150 aa)
	A0A182PB99	Uncharacterized protein. (489 aa)

Your Current Organism:

Anopheles epiroticus

NCBI taxonomy Id: 199890
Other names: A. epiroticus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182P0P5	A0A182P4K2	Elongation of very long chain fatty acids protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.667
A0A182P0P5	A0A182P769	Elongation of very long chain fatty acids protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.532
A0A182P0P5	A0A182PHX0	Elongation of very long chain fatty acids protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.667
A0A182P0P5	A0A182PM20	Elongation of very long chain fatty acids protein.	S5A_REDUCTASE domain-containing protein.	0.643
A0A182P0P5	A0A182PMB9	Elongation of very long chain fatty acids protein.	Uncharacterized protein.	0.667
A0A182P0P5	A0A182PS01	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein.	0.518
A0A182P0P5	A0A240PPN7	Elongation of very long chain fatty acids protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.532
A0A182P229	A0A182P4K2	Elongation of very long chain fatty acids protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.827
A0A182P229	A0A182P4Z2	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein.	0.473
A0A182P229	A0A182P528	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein.	0.694
A0A182P229	A0A182P769	Elongation of very long chain fatty acids protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.689
A0A182P229	A0A182P7S4	Elongation of very long chain fatty acids protein.	Cytochrome b5 heme-binding domain-containing protein.	0.602
A0A182P229	A0A182PAC8	Elongation of very long chain fatty acids protein.	Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family.	0.639
A0A182P229	A0A182PCI2	Elongation of very long chain fatty acids protein.	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	0.602
A0A182P229	A0A182PHX0	Elongation of very long chain fatty acids protein.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.667
A0A182P229	A0A182PM20	Elongation of very long chain fatty acids protein.	S5A_REDUCTASE domain-containing protein.	0.756
A0A182P229	A0A182PM31	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein.	0.525
A0A182P229	A0A182PM32	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein.	0.537
A0A182P229	A0A182PM33	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein.	0.513
A0A182P229	A0A182PMB9	Elongation of very long chain fatty acids protein.	Uncharacterized protein.	0.712