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| | dapH | Unannotated protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (240 aa) |
| | GCA_900168775_03625 | Unannotated protein. (401 aa) |
| | GCA_900168775_03504 | Unannotated protein. (131 aa) |
| | GCA_900168775_03502 | Unannotated protein. (189 aa) |
| | DES48_10955 | Unannotated protein. (186 aa) |
| | ilvD | Unannotated protein; Belongs to the IlvD/Edd family. (560 aa) |
| | DES48_103151 | Unannotated protein; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (423 aa) |
| | argG | Unannotated protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (419 aa) |
| | argH | Unannotated protein. (476 aa) |
| | DES48_10374 | Unannotated protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (316 aa) |
| | DES48_10336 | Unannotated protein. (170 aa) |
| | DES48_11282 | Unannotated protein. (219 aa) |
| | DES48_1205 | Unannotated protein; Belongs to the cysteine synthase/cystathionine beta- synthase family. (312 aa) |
| | DES48_106115 | Unannotated protein. (320 aa) |
| | aroD | Unannotated protein; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (253 aa) |
| | DES48_10654 | Unannotated protein. (284 aa) |
| | eno | Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (428 aa) |
| | gpmI | Unannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (512 aa) |
| | tpiA | Unannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa) |
| | pgk | Unannotated protein; Belongs to the phosphoglycerate kinase family. (393 aa) |
| | DES48_10640 | Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | DES48_1245 | Unannotated protein. (264 aa) |
| | DES48_102483 | Unannotated protein. (346 aa) |
| | prs | Unannotated protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa) |
| | proC-2 | Unannotated protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (267 aa) |
| | DES48_102446 | Unannotated protein. (368 aa) |
| | DES48_102445 | Unannotated protein. (369 aa) |
| | rpiA | Unannotated protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (227 aa) |
| | DES48_102416 | Unannotated protein. (249 aa) |
| | DES48_102392 | Unannotated protein. (388 aa) |
| | glyA | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa) |
| | DES48_102288 | Unannotated protein. (285 aa) |
| | DES48_102282 | Unannotated protein. (261 aa) |
| | trpA | Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (259 aa) |
| | trpB | Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (401 aa) |
| | trpF | Unannotated protein; Belongs to the TrpF family. (202 aa) |
| | trpC | Unannotated protein; Belongs to the TrpC family. (257 aa) |
| | trpD | Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (340 aa) |
| | DES48_102166 | Unannotated protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (666 aa) |
| | DES48_102164 | Unannotated protein; Belongs to the ribulose-phosphate 3-epimerase family. (220 aa) |
| | DES48_102162 | Unannotated protein. (147 aa) |
| | DES48_102154 | Unannotated protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (214 aa) |
| | argB | Unannotated protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (267 aa) |
| | argJ | Unannotated protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (408 aa) |
| | argC | Unannotated protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (346 aa) |
| | DES48_102120 | Unannotated protein. (100 aa) |
| | DES48_102109 | Unannotated protein. (391 aa) |
| | serC | Unannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (362 aa) |
| | fda | Unannotated protein; Belongs to the class I fructose-bisphosphate aldolase family. (297 aa) |
| | DES48_11317 | Unannotated protein. (152 aa) |
| | DES48_103243 | Unannotated protein. (142 aa) |
| | DES48_103244 | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa) |
| | proC | Unannotated protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa) |
| | leuD | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (196 aa) |
| | metAA | Unannotated protein; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (302 aa) |
| | DES48_10568 | Unannotated protein. (615 aa) |
| | DES48_105104 | Unannotated protein. (387 aa) |
| | DES48_105139 | Unannotated protein. (380 aa) |
| | DES48_105156 | Unannotated protein. (458 aa) |
| | luxS | Unannotated protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (154 aa) |
| | DES48_1075 | Unannotated protein; Belongs to the TPP enzyme family. (571 aa) |
| | DES48_10748 | Unannotated protein. (391 aa) |
| | metK | Unannotated protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (398 aa) |
| | DES48_106133 | Unannotated protein. (392 aa) |
| | dapF | Unannotated protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (286 aa) |
| | thrB | Unannotated protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (295 aa) |
| | DES48_106117 | Unannotated protein; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (353 aa) |
| | DES48_106116 | Unannotated protein. (430 aa) |
| | leuC | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (471 aa) |
| | leuA | Unannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (515 aa) |
| | ilvC | Unannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (343 aa) |
| | DES48_11025 | Unannotated protein. (174 aa) |
| | DES48_11024 | Unannotated protein. (577 aa) |
| | DES48_1108 | Unannotated protein. (385 aa) |
| | DES48_1102 | Unannotated protein; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (374 aa) |
| | DES48_101586 | Unannotated protein; Belongs to the ribulose-phosphate 3-epimerase family. (217 aa) |
| | DES48_101581 | Unannotated protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (220 aa) |
| | DES48_101580 | Unannotated protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (294 aa) |
| | asd | Unannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (348 aa) |
| | DES48_101490 | Unannotated protein; Belongs to the aspartokinase family. (408 aa) |
| | dapA | Unannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | DES48_101455 | Unannotated protein. (444 aa) |
| | DES48_101447 | Unannotated protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa) |
| | DES48_101442 | Unannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (903 aa) |
| | DES48_101425 | Unannotated protein; Belongs to the PHP hydrolase family. HisK subfamily. (275 aa) |
| | hisZ | Unannotated protein; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (374 aa) |
| | hisG | Unannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (206 aa) |
| | hisD | Unannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa) |
| | hisB | Unannotated protein. (195 aa) |
| | hisH | Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (199 aa) |
| | hisA | Unannotated protein. (235 aa) |
| | hisF | Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa) |
| | hisI | Unannotated protein; In the N-terminal section; belongs to the PRA-CH family. (218 aa) |
| | DES48_101402 | Unannotated protein. (1519 aa) |
| | DES48_101400 | Unannotated protein. (359 aa) |
| | proB | Unannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (371 aa) |
| | proA | Unannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (414 aa) |
| | ilvA | Unannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (420 aa) |
| | DES48_101390 | Unannotated protein; Belongs to the cysteine synthase/cystathionine beta- synthase family. (306 aa) |
| | dapA-2 | Unannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa) |
| | DES48_101330 | Unannotated protein. (181 aa) |
| | DES48_101297 | Unannotated protein. (395 aa) |
| | dapB | Unannotated protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (266 aa) |
| | aroA | Unannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (429 aa) |
| | DES48_101276 | Unannotated protein. (366 aa) |
| | hisC | Unannotated protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (368 aa) |
| | DES48_101274 | Unannotated protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (121 aa) |
| | aroB | Unannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (359 aa) |
| | aroC | Unannotated protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (387 aa) |
| | DES48_101247 | Unannotated protein. (211 aa) |
| | DES48_101241 | Unannotated protein. (358 aa) |
| | lysA | Unannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (432 aa) |
| | GCA_900168775_02115 | Unannotated protein. (200 aa) |
| | rex | Unannotated protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (214 aa) |
| | DES48_10428 | Unannotated protein. (353 aa) |
| | pfkA | Unannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (318 aa) |
| | pfkA-2 | Unannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa) |
| | DES48_10472 | Unannotated protein; Belongs to the pyruvate kinase family. (587 aa) |
| | DES48_10473 | Unannotated protein. (129 aa) |
| | DES48_10476 | Unannotated protein; Belongs to the citrate synthase family. (372 aa) |
| | DES48_10477 | Unannotated protein. (424 aa) |
| | DES48_104134 | Unannotated protein. (369 aa) |
| | DES48_1167 | Unannotated protein; Belongs to the UPF0735 family. (149 aa) |
| | pheA | Unannotated protein. (284 aa) |
| | DES48_1012 | Unannotated protein. (322 aa) |
| | mtnN | Unannotated protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (230 aa) |
| | aroE | Unannotated protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (278 aa) |
| | aroK | Unannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (166 aa) |
| | DES48_101184 | Unannotated protein; Belongs to the aspartokinase family. (450 aa) |
| | DES48_101198 | Unannotated protein. (332 aa) |
| | DES48_11117 | Unannotated protein. (140 aa) |
| | DES48_10841 | Unannotated protein; Belongs to the UPF0237 family. (90 aa) |
| | DES48_108142 | Unannotated protein. (357 aa) |
| | DES48_11448 | Unannotated protein. (96 aa) |
| | rsmA | Unannotated protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (288 aa) |
| | prs-2 | Unannotated protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa) |
| | DES48_1147 | Unannotated protein; Belongs to the phosphoglycerate mutase family. (188 aa) |
