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folD folD asd asd ALS74055.1 ALS74055.1 ALS74057.1 ALS74057.1 dxs dxs ALS74170.1 ALS74170.1 mtnN mtnN accA accA accD accD thiI thiI metK metK ALS74719.1 ALS74719.1 ALS74745.1 ALS74745.1 ALS74747.1 ALS74747.1 ALS74765.1 ALS74765.1 ALS74891.1 ALS74891.1 ALS75026.1 ALS75026.1 ALS75088.1 ALS75088.1 ALS75153.1 ALS75153.1 ALS75489.1 ALS75489.1 ALS75504.1 ALS75504.1 mmuM mmuM lipA lipA metXA metXA ALS76184.1 ALS76184.1 ALS76189.1 ALS76189.1 ALS76198.1 ALS76198.1 ALS76199.1 ALS76199.1 ALS76201.1 ALS76201.1 lipL lipL ALS76307.1 ALS76307.1 ALS76313.1 ALS76313.1 thiM thiM thiE thiE ALS77111.1 ALS77111.1 ALS76516.1 ALS76516.1 ALS76518.1 ALS76518.1 ALS76625.1 ALS76625.1 ALS76798.1 ALS76798.1 ALS76849.1 ALS76849.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (291 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (336 aa)
ALS74055.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
ALS74057.1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (636 aa)
ALS74170.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
mtnN5'-methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (234 aa)
accAacetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (321 aa)
accDGntR family transcriptional regulator; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa)
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (400 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (398 aa)
ALS74719.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
ALS74745.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (305 aa)
ALS74747.1Nitrate/sulfonate/bicarbonate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
ALS74765.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (146 aa)
ALS74891.15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
ALS75026.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1145 aa)
ALS75088.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
ALS75153.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
ALS75489.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
ALS75504.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (313 aa)
mmuMConverts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (314 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (339 aa)
ALS76184.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
ALS76189.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
ALS76198.1Bacillithiol biosynthesis deacetylase BshB2; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
ALS76199.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
ALS76201.1Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Catalyzes the phosphorylation of three vitamin B6 precursors, pyridoxal, pyridoxine and pyridoxamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
lipLOctanoyltransferase; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family. (273 aa)
ALS76307.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (292 aa)
ALS76313.1Thiaminase II; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. (229 aa)
thiMHydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (253 aa)
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (229 aa)
ALS77111.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
ALS76516.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (422 aa)
ALS76518.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (417 aa)
ALS76625.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
ALS76798.1Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
ALS76849.1Thiamine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
Your Current Organism:
Planococcus rifietoensis
NCBI taxonomy Id: 200991
Other names: ATCC BAA-790, DSM 15069, P. rifietoensis, Planococcus rifietensis, Planococcus rifietoensis corrig. Romano et al. 2003, Planococcus rifitiensis, strain M8
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