(23 nodes) IRS-mediated signalling network (Ooceraea biroi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	X777_11716	Proto-oncogene tyrosine-protein kinase receptor Ret; Belongs to the protein kinase superfamily. Tyr protein kinase family. (975 aa)
	X777_11717	Uncharacterized protein. (219 aa)
	X777_11265	Fibroblast growth factor receptor substrate. (371 aa)
	X777_11641	Saposin A-type domain-containing protein. (141 aa)
	X777_11412	Protein daughter of sevenless. (598 aa)
	X777_10030	Protein son of sevenless. (1327 aa)
	X777_08020	Tyrosine kinase receptor Cad96Ca; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1551 aa)
	DMN91_007918	Insulin receptor substrate 1-B. (1292 aa)
	DMN91_004547	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1079 aa)
	X777_07125	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (234 aa)
	X777_02365	Fibroblast growth factor receptor. (1075 aa)
	X777_02235	Myrosinase; Belongs to the glycosyl hydrolase 1 family. (500 aa)
	X777_02148	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
	DMN91_002789	Tribbles-like protein. (364 aa)
	X777_01354	Fibroblast growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1615 aa)
	X777_01528	Fibroblast growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. (572 aa)
	DMN91_008089	Protein E(Sev)2B. (211 aa)
	X777_16913	3-phosphoinositide-dependent protein kinase. (571 aa)
	DMN91_009603	Non-specific serine/threonine protein kinase. (554 aa)
	X777_02381	Tyrosine kinase receptor Cad96Ca; Belongs to the protein kinase superfamily. Tyr protein kinase family. (600 aa)
	X777_12875	Uncharacterized protein. (430 aa)
	X777_11639	Tyrosine-protein kinase receptor. (2516 aa)
	X777_11654	Phosphatidylinositol 3-kinase regulatory subunit alpha. (867 aa)

Your Current Organism:

Ooceraea biroi

NCBI taxonomy Id: 2015173
Other names: Cerapachys biroi, O. biroi, clonal raider ant

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DMN91_002789	DMN91_009603	A0A026WQ26	A0A026WVT4	Tribbles-like protein.	Non-specific serine/threonine protein kinase.	0.891
DMN91_002789	X777_16913	A0A026WQ26	A0A026WV25	Tribbles-like protein.	3-phosphoinositide-dependent protein kinase.	0.644
DMN91_004547	DMN91_007918	A0A026WCF3	A0A026WC73	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Insulin receptor substrate 1-B.	0.859
DMN91_004547	DMN91_008089	A0A026WCF3	A0A026WTT4	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Protein E(Sev)2B.	0.761
DMN91_004547	DMN91_009603	A0A026WCF3	A0A026WVT4	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Non-specific serine/threonine protein kinase.	0.923
DMN91_004547	X777_01354	A0A026WCF3	A0A026WQS4	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Fibroblast growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.469
DMN91_004547	X777_01528	A0A026WCF3	A0A026WSV1	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Fibroblast growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.425
DMN91_004547	X777_02148	A0A026WCF3	A0A026WNV1	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.515
DMN91_004547	X777_02235	A0A026WCF3	A0A026WLX1	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Myrosinase; Belongs to the glycosyl hydrolase 1 family.	0.481
DMN91_004547	X777_02365	A0A026WCF3	A0A026WLD5	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Fibroblast growth factor receptor.	0.469
DMN91_004547	X777_02381	A0A026WCF3	A0A026VTA7	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Tyrosine kinase receptor Cad96Ca; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.469
DMN91_004547	X777_07125	A0A026WCF3	A0A026WCG8	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.465
DMN91_004547	X777_08020	A0A026WCF3	A0A026WA62	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Tyrosine kinase receptor Cad96Ca; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.469
DMN91_004547	X777_10030	A0A026WCF3	A0A026W5J5	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Protein son of sevenless.	0.799
DMN91_004547	X777_11412	A0A026WCF3	A0A026W4F4	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Protein daughter of sevenless.	0.664
DMN91_004547	X777_11639	A0A026WCF3	A0A026W126	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Tyrosine-protein kinase receptor.	0.496
DMN91_004547	X777_11641	A0A026WCF3	A0A026W3Z8	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Saposin A-type domain-containing protein.	0.496
DMN91_004547	X777_11654	A0A026WCF3	A0A026W141	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 3-kinase regulatory subunit alpha.	0.999
DMN91_004547	X777_11716	A0A026WCF3	A0A026W1V9	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Proto-oncogene tyrosine-protein kinase receptor Ret; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.469
DMN91_004547	X777_11717	A0A026WCF3	A0A026W1Z4	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.469