node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DMN91_001910 | DMN91_002694 | A0A026W0T2 | A0A026VZI2 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | BRCA1-A complex subunit BRE. | 0.438 |
DMN91_001910 | DMN91_002792 | A0A026W0T2 | A0A026WIZ1 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Cyclin-dependent kinase; Belongs to the protein kinase superfamily. | 0.491 |
DMN91_001910 | DMN91_003887 | A0A026W0T2 | A0A026WZR6 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Serine/threonine-protein kinase Chk2. | 0.651 |
DMN91_001910 | DMN91_006142 | A0A026W0T2 | A0A026WDU5 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | E3 ubiquitin-protein ligase. | 0.481 |
DMN91_001910 | X777_04559 | A0A026W0T2 | A0A026WIL2 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Uncharacterized protein. | 0.878 |
DMN91_001910 | X777_05067 | A0A026W0T2 | A0A026WFE5 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Tumor suppressor p53-binding protein. | 0.911 |
DMN91_001910 | X777_06749 | A0A026W0T2 | A0A026X1X2 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Breast cancer type 1 susceptibility protein-like protein. | 0.538 |
DMN91_001910 | X777_08168 | A0A026W0T2 | A0A026WYX5 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | E3 ubiquitin-protein ligase RNF8-A. | 0.427 |
DMN91_001910 | X777_09468 | A0A026W0T2 | A0A026W6H6 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.469 |
DMN91_001910 | X777_12084 | A0A026W0T2 | A0A026W3C4 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Ankyrin repeat domain-containing protein. | 0.622 |
DMN91_001910 | X777_15629 | A0A026W0T2 | A0A026VUU8 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Uncharacterized protein. | 0.878 |
DMN91_001910 | X777_16158 | A0A026W0T2 | A0A026WV78 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Serine/threonine-protein kinase atr; Belongs to the PI3/PI4-kinase family. | 0.452 |
DMN91_002694 | DMN91_001910 | A0A026VZI2 | A0A026W0T2 | BRCA1-A complex subunit BRE. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.438 |
DMN91_002694 | DMN91_003887 | A0A026VZI2 | A0A026WZR6 | BRCA1-A complex subunit BRE. | Serine/threonine-protein kinase Chk2. | 0.511 |
DMN91_002694 | DMN91_004632 | A0A026VZI2 | A0A026WYT5 | BRCA1-A complex subunit BRE. | BRISC and BRCA1-A complex member. | 0.999 |
DMN91_002694 | DMN91_006142 | A0A026VZI2 | A0A026WDU5 | BRCA1-A complex subunit BRE. | E3 ubiquitin-protein ligase. | 0.484 |
DMN91_002694 | DMN91_008365 | A0A026VZI2 | A0A026W0T1 | BRCA1-A complex subunit BRE. | Lys-63-specific deubiquitinase BRCC36. | 0.999 |
DMN91_002694 | X777_01859 | A0A026VZI2 | A0A026X5S5 | BRCA1-A complex subunit BRE. | Uncharacterized protein. | 0.788 |
DMN91_002694 | X777_05067 | A0A026VZI2 | A0A026WFE5 | BRCA1-A complex subunit BRE. | Tumor suppressor p53-binding protein. | 0.500 |
DMN91_002694 | X777_06749 | A0A026VZI2 | A0A026X1X2 | BRCA1-A complex subunit BRE. | Breast cancer type 1 susceptibility protein-like protein. | 0.888 |