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| | X777_12749 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (882 aa) |
| | X777_14206 | Uncharacterized protein. (422 aa) |
| | DMN91_011610 | Proteasome inhibitor PI31 subunit. (285 aa) |
| | X777_01859 | Uncharacterized protein. (115 aa) |
| | X777_07539 | Replication factor C subunit. (359 aa) |
| | DMN91_005511 | Proteasome subunit beta. (207 aa) |
| | DMN91_006822 | Proteasome subunit beta. (277 aa) |
| | DMN91_008166 | Cell division cycle protein 27-like protein. (845 aa) |
| | DMN91_002614 | Ubiquitin-60S ribosomal protein L40. (128 aa) |
| | X777_10056 | DNA endonuclease RBBP8. (513 aa) |
| | DMN91_003594 | 26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (428 aa) |
| | DMN91_005747 | Uncharacterized protein. (74 aa) |
| | X777_00626 | Proteasome subunit beta; Belongs to the peptidase T1B family. (241 aa) |
| | DMN91_003992 | 26S proteasome non-ATPase regulatory subunit. (310 aa) |
| | X777_06749 | Breast cancer type 1 susceptibility protein-like protein. (1666 aa) |
| | X777_04707 | Microtubule-associated protein RP/EB family member. (371 aa) |
| | X777_04729 | Origin recognition complex subunit. (573 aa) |
| | X777_04651 | B9 domain-containing protein. (827 aa) |
| | X777_13121 | MCM10-like protein. (559 aa) |
| | DMN91_003977 | Spindle and kinetochore-associated protein. (300 aa) |
| | X777_11583 | Cell cycle checkpoint protein RAD17. (300 aa) |
| | DMN91_007492 | Mitotic checkpoint protein BUB3. (326 aa) |
| | DMN91_003887 | Serine/threonine-protein kinase Chk2. (483 aa) |
| | DMN91_005359 | Anaphase-promoting complex subunit; Belongs to the cullin family. (777 aa) |
| | X777_08360 | Zwilch-like protein. (714 aa) |
| | X777_08168 | E3 ubiquitin-protein ligase RNF8-A. (468 aa) |
| | DMN91_004632 | BRISC and BRCA1-A complex member. (320 aa) |
| | X777_08359 | Uncharacterized protein. (182 aa) |
| | DMN91_005344 | Kinetochore protein NDC80-like protein. (648 aa) |
| | X777_13063 | Cell division cycle protein 23-like protein. (288 aa) |
| | DMN91_008061 | Cyclin-A1; Belongs to the cyclin family. (472 aa) |
| | X777_08282 | Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family. (127 aa) |
| | DMN91_005086 | Proteasome subunit beta. (288 aa) |
| | DMN91_006758 | Werner Syndrome-like exonuclease. (292 aa) |
| | X777_00092 | Uncharacterized protein. (140 aa) |
| | X777_00003 | DNA replication licensing factor MCM8. (58 aa) |
| | X777_01088 | Cell division cycle protein 23-like protein. (539 aa) |
| | X777_15629 | Uncharacterized protein. (132 aa) |
| | X777_15450 | Anaphase-promoting complex subunit. (1970 aa) |
| | X777_15485 | Uncharacterized protein. (817 aa) |
| | X777_15478 | X-linked retinitis pigmentosa GTPase regulator-like protein. (1721 aa) |
| | DMN91_005045 | Mitotic spindle assembly checkpoint protein MAD2A. (214 aa) |
| | X777_13127 | Uncharacterized protein. (1397 aa) |
| | DMN91_009557 | Ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | X777_13560 | Claspin. (1064 aa) |
| | X777_13582 | Proteasome activator complex subunit. (1525 aa) |
| | DMN91_010767 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (246 aa) |
| | X777_16662 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (459 aa) |
| | DMN91_010533 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (249 aa) |
| | DMN91_010701 | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (480 aa) |
| | X777_15090 | Spindle and kinetochore-associated protein. (187 aa) |
| | X777_15080 | 26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (266 aa) |
| | X777_15104 | Anaphase-promoting complex subunit. (572 aa) |
| | X777_15887 | DNA helicase; Belongs to the MCM family. (880 aa) |
| | DMN91_008083 | Putative cell division control protein 7-like protein; Belongs to the protein kinase superfamily. (419 aa) |
| | X777_16158 | Serine/threonine-protein kinase atr; Belongs to the PI3/PI4-kinase family. (2515 aa) |
| | DMN91_008156 | 26S proteasome non-ATPase regulatory subunit. (208 aa) |
| | DMN91_010795 | Proteasome subunit beta type-6. (231 aa) |
| | X777_15916 | Mitotic spindle assembly checkpoint protein MAD1. (677 aa) |
| | DMN91_008095 | Putative 26S proteasome non-ATPase regulatory subunit. (503 aa) |
| | X777_15000 | C2H2-type domain-containing protein. (177 aa) |
| | DMN91_008501 | 26S proteasome non-ATPase regulatory subunit. (385 aa) |
| | X777_14981 | 26S protease regulatory subunit; Belongs to the AAA ATPase family. (434 aa) |
| | X777_14792 | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (564 aa) |
| | X777_00886 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (958 aa) |
| | X777_14791 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform. (164 aa) |
| | X777_01238 | Polyubiquitin-A. (839 aa) |
| | X777_14680 | DNA topoisomerase 2-binding protein 1-A. (1334 aa) |
| | X777_01365 | 14-3-3 protein zeta; Belongs to the 14-3-3 family. (309 aa) |
| | DMN91_006001 | G1/S-specific cyclin-E; Belongs to the cyclin family. (454 aa) |
| | X777_02600 | KxDL domain-containing protein. (201 aa) |
| | X777_01894 | RCC1 and BTB domain-containing protein. (505 aa) |
| | X777_01571 | 26S proteasome non-ATPase regulatory subunit. (231 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (725 aa) |
| | DMN91_007073 | 26S proteasome non-ATPase regulatory subunit. (387 aa) |
| | X777_00825 | 14-3-3 protein epsilon; Belongs to the 14-3-3 family. (234 aa) |
| | X777_02567 | Uncharacterized protein. (588 aa) |
| | X777_02313 | Uncharacterized protein. (295 aa) |
| | X777_01817 | Uncharacterized protein. (1315 aa) |
| | DMN91_003116 | Ubiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (187 aa) |
| | DMN91_003294 | DNA helicase; Belongs to the MCM family. (891 aa) |
| | X777_02566 | Anaphase-promoting complex subunit. (86 aa) |
| | DMN91_007161 | DNA helicase; Belongs to the MCM family. (817 aa) |
| | DMN91_007213 | Serine/threonine-protein kinase grp; Belongs to the protein kinase superfamily. (454 aa) |
| | X777_01659 | 26S proteasome non-ATPase regulatory subunit. (267 aa) |
| | DMN91_000875 | 26S proteasome non-ATPase regulatory subunit. (503 aa) |
| | X777_03604 | RCC1 and BTB domain-containing protein. (487 aa) |
| | DMN91_000796 | Origin recognition complex subunit. (574 aa) |
| | DMN91_000821 | Replication protein A 32 kDa subunit. (244 aa) |
| | X777_02874 | Centromere protein I. (527 aa) |
| | DMN91_010041 | Replication factor C subunit. (352 aa) |
| | DMN91_002664 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (893 aa) |
| | X777_03673 | Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (211 aa) |
| | DMN91_002792 | Cyclin-dependent kinase; Belongs to the protein kinase superfamily. (297 aa) |
| | DMN91_011285 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (257 aa) |
| | X777_04559 | Uncharacterized protein. (100 aa) |
| | X777_03939 | DNA helicase. (785 aa) |
| | X777_05064 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (526 aa) |
| | X777_04225 | Exonuclease 3'-5' domain-containing protein. (620 aa) |
| | X777_04855 | Piezo-type mechanosensitive ion channel component. (2455 aa) |
| | X777_03825 | Tumor protein p73. (232 aa) |
| | DMN91_000031 | Replication factor C subunit. (354 aa) |
| | DMN91_008933 | DNA helicase; Belongs to the MCM family. (733 aa) |
| | DMN91_001351 | Gamma-glutamylcyclotransferase. (176 aa) |
| | X777_04482 | Uncharacterized protein. (408 aa) |
| | X777_05043 | G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (580 aa) |
| | X777_05097 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (1000 aa) |
| | X777_05067 | Tumor suppressor p53-binding protein. (1427 aa) |
| | DMN91_007313 | RCC1 and BTB domain-containing protein. (547 aa) |
| | X777_05070 | Serine-protein kinase ATM; Belongs to the PI3/PI4-kinase family. (2637 aa) |
| | X777_04990 | RecQ-mediated genome instability protein. (604 aa) |
| | DMN91_001497 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (234 aa) |
| | DMN91_001639 | Protein chiffon. (1600 aa) |
| | DMN91_006142 | E3 ubiquitin-protein ligase. (877 aa) |
| | X777_06007 | Checkpoint protein; Belongs to the HUS1 family. (274 aa) |
| | X777_05813 | Cell cycle checkpoint protein RAD1. (353 aa) |
| | X777_07988 | Uncharacterized protein. (109 aa) |
| | X777_08509 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (542 aa) |
| | X777_07075 | E3 ubiquitin-protein ligase RFWD2. (1181 aa) |
| | DMN91_004245 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (242 aa) |
| | DMN91_005011 | Cell division cycle protein 16-like protein. (653 aa) |
| | X777_06938 | Reverse transcriptase domain-containing protein. (138 aa) |
| | X777_07379 | Anaphase-promoting complex subunit. (721 aa) |
| | X777_07422 | Proteasome subunit beta type-4. (121 aa) |
| | X777_07676 | Uncharacterized protein. (617 aa) |
| | X777_07099 | 26S protease regulatory subunit; Belongs to the AAA ATPase family. (235 aa) |
| | DMN91_010074 | 26S proteasome non-ATPase regulatory subunit. (423 aa) |
| | X777_09641 | Uncharacterized protein. (320 aa) |
| | DMN91_006936 | G2/mitotic-specific cyclin-B; Belongs to the cyclin family. (436 aa) |
| | X777_08897 | Mitotic checkpoint serine/threonine-protein kinase BUB1. (1446 aa) |
| | X777_08674 | Proteasome activator complex subunit. (246 aa) |
| | DMN91_011511 | Tudor domain-containing protein. (726 aa) |
| | X777_09432 | Glioma tumor suppressor candidate region gene 1 protein. (2289 aa) |
| | X777_09278 | DNA replication licensing factor MCM9; Belongs to the MCM family. (620 aa) |
| | X777_09771 | DNA replication licensing factor MCM8; Belongs to the MCM family. (243 aa) |
| | X777_09441 | Uncharacterized protein. (127 aa) |
| | X777_09207 | Uncharacterized protein. (156 aa) |
| | X777_09464 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (191 aa) |
| | X777_09963 | 26S protease regulatory subunit; Belongs to the AAA ATPase family. (440 aa) |
| | X777_09468 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (554 aa) |
| | DMN91_003621 | 26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (415 aa) |
| | X777_09772 | DNA replication licensing factor MCM8; Belongs to the MCM family. (290 aa) |
| | X777_10379 | Kinetochore-associated protein. (1777 aa) |
| | X777_09669 | Wee1-like protein kinase. (624 aa) |
| | DMN91_012603 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (278 aa) |
| | X777_10962 | Uncharacterized protein. (252 aa) |
| | X777_10709 | CAP-Gly domain-containing linker protein. (1607 aa) |
| | X777_11036 | 26S proteasome non-ATPase regulatory subunit. (389 aa) |
| | X777_12084 | Ankyrin repeat domain-containing protein. (785 aa) |
| | X777_12247 | Anaphase-promoting complex subunit. (749 aa) |
| | DMN91_009625 | 26S proteasome non-ATPase regulatory subunit. (320 aa) |
| | DMN91_008924 | Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (254 aa) |
| | X777_11296 | Uncharacterized protein. (107 aa) |
| | DMN91_005305 | Proteasome subunit beta. (205 aa) |
| | X777_12552 | CLIP-associating protein. (1155 aa) |
| | X777_11595 | Cyclin-dependent kinase; Belongs to the protein kinase superfamily. (299 aa) |
| | DMN91_001910 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | DMN91_008365 | Lys-63-specific deubiquitinase BRCC36. (253 aa) |
| | DMN91_006415 | Uncharacterized protein. (136 aa) |
| | X777_12554 | CLIP-associating protein. (235 aa) |
| | X777_12165 | Uncharacterized protein. (116 aa) |
| | X777_12117 | Nuclear distribution protein nudE-like 1-A. (315 aa) |
| | X777_12255 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (449 aa) |
| | DMN91_010015 | Replication factor C subunit. (328 aa) |
| | X777_12343 | Cytoskeleton-associated protein. (941 aa) |
| | X777_12553 | Uncharacterized protein. (70 aa) |
| | DMN91_002694 | BRCA1-A complex subunit BRE. (391 aa) |
| | X777_14518 | Cell cycle checkpoint control protein RAD9A. (466 aa) |
| | X777_13679 | 26S proteasome non-ATPase regulatory subunit. (351 aa) |
| | X777_12779 | Cell division control protein 45-like protein. (563 aa) |
| | DMN91_001357 | Polyubiquitin-A. (458 aa) |
