STRINGSTRING
thiG thiG SFF67320.1 SFF67320.1 SFF67332.1 SFF67332.1 thiE thiE thiM thiM thiE-2 thiE-2 SFF87437.1 SFF87437.1 SFG03770.1 SFG03770.1 SFG03799.1 SFG03799.1 thiC thiC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (255 aa)
SFF67320.1Sulfur carrier protein. (58 aa)
SFF67332.1Glycine oxidase. (370 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (222 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (269 aa)
thiE-2Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (227 aa)
SFF87437.1Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (268 aa)
SFG03770.1Molybdopterin synthase catalytic subunit. (240 aa)
SFG03799.1Adenylyltransferase and sulfurtransferase. (342 aa)
thiCHydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (582 aa)
Your Current Organism:
Planifilum fulgidum
NCBI taxonomy Id: 201973
Other names: ATCC BAA-970, DSM 44945, JCM 12508, P. fulgidum, Planifilum fulgidum Hatayama et al. 2005, Planifilum fulgidus, Thermoactinomyces sp. 500275, Thermoactinomyces sp. 700375, Thermoactinomyces sp. C0170, strain 500275
Server load: low (22%) [HD]