STRINGSTRING
SFF75373.1 SFF75373.1 SFF75387.1 SFF75387.1 SFF75404.1 SFF75404.1 menG menG SFF75440.1 SFF75440.1 ubiX ubiX mqnA mqnA SFF75489.1 SFF75489.1 mqnC mqnC mqnD mqnD mqnB mqnB SFG06123.1 SFG06123.1 mqnE mqnE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SFF75373.1Transcription attenuation protein (tryptophan RNA-binding attenuator protein). (71 aa)
SFF75387.1Hypothetical protein. (168 aa)
SFF75404.1Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1. (255 aa)
menGDemethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (250 aa)
SFF75440.14-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family. (293 aa)
ubiX4-hydroxy-3-polyprenylbenzoate decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (197 aa)
mqnAChorismate dehydratase; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (280 aa)
SFF75489.1Heptaprenyl diphosphate synthase; Belongs to the FPP/GGPP synthase family. (361 aa)
mqnCDe-hypoxanthine futalosine cyclase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (369 aa)
mqnD1,4-dihydroxy-6-naphthoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (276 aa)
mqnBFutalosine hydrolase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). (223 aa)
SFG06123.1Menaquinone biosynthesis decarboxylase, SCO4490 family; Belongs to the UbiD family. (585 aa)
mqnEAminodeoxyfutalosine synthase; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (365 aa)
Your Current Organism:
Planifilum fulgidum
NCBI taxonomy Id: 201973
Other names: ATCC BAA-970, DSM 44945, JCM 12508, P. fulgidum, Planifilum fulgidum Hatayama et al. 2005, Planifilum fulgidus, Thermoactinomyces sp. 500275, Thermoactinomyces sp. 700375, Thermoactinomyces sp. C0170, strain 500275
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.