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Cthe_0043 Cthe_0043 celI celI Cthe_0413 Cthe_0413 Cthe_2360 Cthe_2360 Cthe_2423 Cthe_2423 Cthe_2506 Cthe_2506 Cthe_2760 Cthe_2760 Cthe_0735 Cthe_0735 Cthe_0625 Cthe_0625 Cthe_0452 Cthe_0452 Cthe_0433 Cthe_0433 celF celF Cthe_0578 Cthe_0578 Cthe_2761 Cthe_2761 cipA cipA olpB olpB Cthe_3079 Cthe_3079 ancA ancA Cthe_0736 Cthe_0736 Cthe_0745 Cthe_0745 Cthe_1257 Cthe_1257 Cthe_1307 Cthe_1307 Cthe_2147 Cthe_2147 rsgI4 rsgI4 Cthe_0271 Cthe_0271 rsgI2 rsgI2 Cthe_0071 Cthe_0071 rsgI1 rsgI1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Cthe_0043PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; Dockerin type 1; KEGG: cce:Ccel_0231 glycoside hydrolase family 9. (742 aa)
celIGlycoside hydrolase family 9; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. Principally active against barley beta-glucan; Belongs to the glycosyl hydrolase 9 (cellulase E) family. (887 aa)
Cthe_0413PFAM: glycoside hydrolase family 9; Carbohydrate-binding CenC domain protein; type 3a cellulose-binding domain protein; Dockerin type 1; KEGG: cce:Ccel_0732 glycoside hydrolase family 9; Belongs to the glycosyl hydrolase 9 (cellulase E) family. (1224 aa)
Cthe_2360PFAM: glycoside hydrolase family 9; Dockerin type 1; type 3a cellulose-binding domain protein; KEGG: cce:Ccel_1648 glycoside hydrolase family 9. (928 aa)
Cthe_2423PFAM: type 3a cellulose-binding domain protein; KEGG: ace:Acel_0616 cellulose-binding family II protein. (998 aa)
Cthe_2506PFAM: S-layer domain-containing protein; Laminin G sub domain 2; type 3a cellulose-binding domain protein; KEGG: bpd:BURPS668_A0166 rhs element Vgr protein. (1013 aa)
Cthe_2760PFAM: glycoside hydrolase family 9; Dockerin type 1; type 3a cellulose-binding domain protein; KEGG: cce:Ccel_1648 glycoside hydrolase family 9. (961 aa)
Cthe_0735PFAM: cellulosome anchoring protein cohesin region; KEGG: bbz:BbuZS7_I25 putative surface antigen. (268 aa)
Cthe_0625PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; Dockerin type 1; KEGG: ate:Athe_1867 glycoside hydrolase family 48; Belongs to the glycosyl hydrolase 9 (cellulase E) family. (710 aa)
Cthe_0452PFAM: cellulosome anchoring protein cohesin region; copper amine oxidase-like domain-containing protein; KEGG: cce:Ccel_0733 cellulosome anchoring protein cohesin region. (257 aa)
Cthe_0433PFAM: glycoside hydrolase family 9; Dockerin type 1; KEGG: cce:Ccel_0753 glycoside hydrolase family 9. (789 aa)
celFGlycoside hydrolase family 9; This enzyme catalyzes the endohydrolysis of 1,4-beta- glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans. (739 aa)
Cthe_0578PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; Dockerin type 1; KEGG: ate:Athe_1867 glycoside hydrolase family 48; Belongs to the glycosyl hydrolase 9 (cellulase E) family. (736 aa)
Cthe_2761PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; Dockerin type 1; KEGG: cce:Ccel_1249 glycoside hydrolase family 9; Belongs to the glycosyl hydrolase 9 (cellulase E) family. (707 aa)
cipACellulosome anchoring protein cohesin region; Acts as a scaffolding protein in the cellulosome. It promotes binding of cellulose to the catalytic domains of the cellulolytic enzymes. (1853 aa)
olpBPFAM: cellulosome anchoring protein cohesin region; S-layer domain-containing protein; KEGG: lel:LELG_02536 hypothetical protein. (2313 aa)
Cthe_3079PFAM: cellulosome anchoring protein cohesin region; S-layer domain-containing protein; KEGG: lsp:Bsph_2088 cell surface glycoprotein 2 precursor (S-layer protein 2). (688 aa)
ancACellulosome anchoring protein cohesin region; Anchors the cellulosome to the cell surface by binding the duplicated segment that is present at the C-terminal end of CipA. (447 aa)
Cthe_0736PFAM: cellulosome anchoring protein cohesin region; KEGG: ate:Athe_1866 mannan endo-1,4-beta-mannosidase., cellulase. (1305 aa)
Cthe_0745PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; Dockerin type 1; KEGG: cce:Ccel_0731 glycoside hydrolase family 9; Belongs to the glycosyl hydrolase 9 (cellulase E) family. (730 aa)
Cthe_1257Carbohydrate-binding CenC domain protein; KEGG: csc:Csac_1076 glycoside hydrolase family protein; PFAM: Carbohydrate-binding CenC domain protein; type 3a cellulose-binding domain protein; SMART: von Willebrand factor type A. (1050 aa)
Cthe_1307PFAM: cellulosome anchoring protein cohesin region; S-layer domain-containing protein; KEGG: hmo:HM1_0137 multidomain protein with S-layer homology region, glug motif, ig motif, I-set domain, pkd domain. (631 aa)
Cthe_2147PFAM: glycoside hydrolase family 5; Dockerin type 1; type 3a cellulose-binding domain protein; KEGG: csc:Csac_1078 cellulose 1,4-beta-cellobiosidase. (660 aa)
rsgI4Type 3a cellulose-binding domain protein; Anti-sigma factor for SigI4. Negatively regulates SigI4 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI4 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI4. (522 aa)
Cthe_0271PFAM: type 3a cellulose-binding domain protein; KEGG: ate:Athe_1860 glycoside hydrolase family 48. (308 aa)
rsgI2Type 3a cellulose-binding domain protein; Anti-sigma factor for SigI2. Negatively regulates SigI2 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI2 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI2. (671 aa)
Cthe_0071KEGG: cpy:Cphy_3368 cellulose 1,4-beta-cellobiosidase; PFAM: glycoside hydrolase family 48; type 3a cellulose-binding domain protein. (938 aa)
rsgI1Type 3a cellulose-binding domain protein; Anti-sigma factor for SigI1. Negatively regulates SigI1 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI1 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI1 (Probable). (486 aa)
Your Current Organism:
Hungateiclostridium thermocellum
NCBI taxonomy Id: 203119
Other names: Clostridium thermocellum ATCC 27405, H. thermocellum ATCC 27405, Hungateiclostridium thermocellum ATCC 27405, Ruminiclostridium thermocellum ATCC 27405
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