STRINGSTRING
gcvT gcvT gcvH gcvH glyA glyA Sde_0502 Sde_0502 Sde_0830 Sde_0830 acsA-2 acsA-2 Sde_1330 Sde_1330 Sde_1382 Sde_1382 Sde_1621 Sde_1621 mdh mdh Sde_1893 Sde_1893 Sde_1991 Sde_1991 Sde_2104 Sde_2104 Sde_2111 Sde_2111 purU purU gcvP gcvP Sde_2645 Sde_2645 Sde_2970 Sde_2970 Sde_3149 Sde_3149 Sde_3207 Sde_3207
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (363 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (130 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa)
Sde_0502L-glutamine synthetase. (468 aa)
Sde_0830Catalase. (480 aa)
acsA-2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa)
Sde_13303-oxoacyl-[acyl-carrier-protein] reductase. (240 aa)
Sde_13822-keto-3-deoxy-phosphogluconate aldolase. (209 aa)
Sde_1621HAD-superfamily hydrolase, subfamily IA, variant 1. (214 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (327 aa)
Sde_1893Aconitase / transcriptional regulator, XRE family; Belongs to the aconitase/IPM isomerase family. (874 aa)
Sde_1991Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (937 aa)
Sde_2104Dihydrolipoamide dehydrogenase. (484 aa)
Sde_2111Citrate synthase; Belongs to the citrate synthase family. (454 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (293 aa)
gcvPGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (964 aa)
Sde_2645Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (481 aa)
Sde_2970Formamidase. (410 aa)
Sde_3149Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
Sde_3207Conserved hypothetical protein. (300 aa)
Your Current Organism:
Saccharophagus degradans
NCBI taxonomy Id: 203122
Other names: Microbulbifer degradans 2-40, Microbulbifer sp. 2-40, S. degradans 2-40, Saccharophagus degradans 2-40, Saccharophagus degradans ATCC 43961, Saccharophagus degradans str. 2-40, Saccharophagus degradans strain 2-40, bacterium 2-40
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