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OEOE_0121 OEOE_0121 OEOE_0161 OEOE_0161 OEOE_0162 OEOE_0162 OEOE_0163 OEOE_0163 OEOE_0165 OEOE_0165 OEOE_0185 OEOE_0185 rexB rexB addA addA OEOE_0378 OEOE_0378 OEOE_0435 OEOE_0435 OEOE_0469 OEOE_0469 OEOE_0493 OEOE_0493 OEOE_0588 OEOE_0588 OEOE_0652 OEOE_0652 OEOE_0667 OEOE_0667 OEOE_0668 OEOE_0668 OEOE_0669 OEOE_0669 OEOE_0670 OEOE_0670 OEOE_0671 OEOE_0671 ddl ddl OEOE_0674 OEOE_0674 mutM mutM coaE coaE OEOE_0677 OEOE_0677 OEOE_0679 OEOE_0679 OEOE_0719 OEOE_0719 OEOE_0805 OEOE_0805 OEOE_0882 OEOE_0882 OEOE_0897 OEOE_0897 OEOE_0900 OEOE_0900 OEOE_0901 OEOE_0901 OEOE_0902 OEOE_0902 OEOE_0903 OEOE_0903 OEOE_0904 OEOE_0904 OEOE_0905 OEOE_0905 OEOE_0906 OEOE_0906 OEOE_0907 OEOE_0907 nadD nadD OEOE_0909 OEOE_0909 rsfS rsfS OEOE_0911 OEOE_0911 tmcAL tmcAL OEOE_0913 OEOE_0913 OEOE_0915 OEOE_0915 OEOE_0916 OEOE_0916 OEOE_0919 OEOE_0919 OEOE_0971 OEOE_0971 OEOE_0972 OEOE_0972 OEOE_1065 OEOE_1065 OEOE_1077 OEOE_1077 OEOE_1093 OEOE_1093 recU recU OEOE_1095 OEOE_1095 OEOE_1140 OEOE_1140 OEOE_1141 OEOE_1141 sepF sepF ftsZ ftsZ ftsA ftsA divIB divIB murG murG murD murD mraY mraY OEOE_1149 OEOE_1149 OEOE_1150 OEOE_1150 rsmH rsmH mraZ mraZ OEOE_1153 OEOE_1153 OEOE_1154 OEOE_1154 OEOE_1155 OEOE_1155 OEOE_1156 OEOE_1156 OEOE_1158 OEOE_1158 OEOE_1160 OEOE_1160 OEOE_1161 OEOE_1161 OEOE_1162 OEOE_1162 OEOE_1163 OEOE_1163 OEOE_1164 OEOE_1164 OEOE_1165 OEOE_1165 OEOE_1166 OEOE_1166 alaS alaS OEOE_1192 OEOE_1192 OEOE_1199 OEOE_1199 OEOE_1200 OEOE_1200 OEOE_1244 OEOE_1244 OEOE_1247 OEOE_1247 OEOE_1261 OEOE_1261 murC murC trmB trmB OEOE_1273 OEOE_1273 OEOE_1274 OEOE_1274 OEOE_1275 OEOE_1275 OEOE_1276 OEOE_1276 OEOE_1277 OEOE_1277 OEOE_1281 OEOE_1281 ezrA ezrA OEOE_1428 OEOE_1428 OEOE_1429 OEOE_1429 OEOE_1430 OEOE_1430 ung ung OEOE_1440 OEOE_1440 OEOE_1442 OEOE_1442 OEOE_1443 OEOE_1443 OEOE_1444 OEOE_1444 OEOE_1446 OEOE_1446 OEOE_1561 OEOE_1561 OEOE_1599 OEOE_1599 OEOE_1600 OEOE_1600 murF murF OEOE_1654 OEOE_1654 OEOE_1655 OEOE_1655 dacA dacA OEOE_1657 OEOE_1657 murB murB OEOE_1659 OEOE_1659 murA murA rpoE rpoE OEOE_1789 OEOE_1789 OEOE_1790 OEOE_1790
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
OEOE_0121D-Ala-D-Ala carboxypeptidase A, Serine peptidase, MEROPS family S11; Belongs to the peptidase S11 family. (440 aa)
OEOE_0161Acetyltransferase, GNAT family. (150 aa)
OEOE_0162Alanine racemase; Catalyzes the interconversion of D-lysine and L-lysine. Can also use arginine and ornithine, but not alanine. (371 aa)
OEOE_0163Thioredoxin reductase. (346 aa)
OEOE_0165Phosphoglycerol transferase-like protein, alkaline phosphatase superfamily. (727 aa)
OEOE_0185Septum formation initiator. (145 aa)
rexBDNA helicase/exodeoxyribonuclease V, subunit B; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' -> 3' nuclease activity; Belongs to the helicase family. AddB/RexB type 2 subfamily. (1161 aa)
addADNA helicase/exodeoxyribonuclease V, subunit A; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily. (1186 aa)
OEOE_0378N-acetylmuramoyl-L-alanine amidase. (286 aa)
OEOE_0435Transcriptional regulator. (427 aa)
OEOE_0469Microcin C7 immunity protein, Serine peptidase, MEROPS family S66. (321 aa)
OEOE_0493Polysaccharide transport membrane protein. (527 aa)
OEOE_0588N-acetylmuramoyl-L-alanine amidase. (315 aa)
OEOE_0652Phosphoglycerol transferase-like protein, alkaline phosphatase superfamily. (744 aa)
OEOE_0667Predicted membrane protein. (73 aa)
OEOE_0668Actin-like ATPase for cell morphogenesis. (374 aa)
OEOE_0669Hypothetical protein. (70 aa)
OEOE_0670Cell division membrane protein; Belongs to the SEDS family. (407 aa)
OEOE_0671Hypothetical protein. (325 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation. (377 aa)
OEOE_0674NUDIX family hydrolase. (177 aa)
mutMFormamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (274 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (204 aa)
OEOE_0677Replicative DNA helicase loader DnaB. (416 aa)
OEOE_0679Predicted hydrocarbon binding protein, V4R domain. (141 aa)
OEOE_0719D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (423 aa)
OEOE_0805Cell wall-associated hydrolase. (395 aa)
OEOE_0882Peptidoglycan interpeptide bridge formation enzyme. (388 aa)
OEOE_0897UDP-N-acetylmuramyl tripeptide synthase; Belongs to the MurCDEF family. MurE subfamily. (499 aa)
OEOE_0900Membrane carboxypeptidase (penicillin-binding protein). (687 aa)
OEOE_0901Hypothetical protein; Belongs to the UPF0342 family. (114 aa)
OEOE_0902DNA repair exonuclease. (413 aa)
OEOE_0903DNA repair ATPase. (821 aa)
OEOE_0904Predicted HD-superfamily hydrolase. (322 aa)
OEOE_0905Predicted hydrolase of the HAD superfamily. (173 aa)
OEOE_0906Predicted GTPase. (385 aa)
OEOE_0907RNA-binding protein, KH domain. (106 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (220 aa)
OEOE_0909NAD metabolism hydrolase of HD superfamily. (189 aa)
rsfSIojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (120 aa)
OEOE_0911SAM-dependent methyltransferase. (246 aa)
tmcALPredicted nucleotidyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (377 aa)
OEOE_0913Predicted metal-binding, possibly nucleic acid-binding protein. (181 aa)
OEOE_0915rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (255 aa)
OEOE_0916Transcriptional regulator. (102 aa)
OEOE_0919Membrane-associated serine protease. (236 aa)
OEOE_0971Hypothetical protein. (101 aa)
OEOE_0972Hypothetical protein. (68 aa)
OEOE_1065D-Ala-D-Ala carboxypeptidase, Metallo peptidase, MEROPS family M15B. (219 aa)
OEOE_1077Fibronectin-binding protein. (547 aa)
OEOE_1093Hypothetical protein; Belongs to the UPF0398 family. (188 aa)
recUPenicillin-binding protein-related factor A, putative recombinase; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. (197 aa)
OEOE_1095Membrane carboxypeptidase (penicillin-binding protein). (879 aa)
OEOE_1140Cell division protein, S4-like domain. (256 aa)
OEOE_1141Cell division membrane protein. (64 aa)
sepFCell division protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (180 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (473 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (439 aa)
divIBCell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. (272 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (373 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (438 aa)
mraYPhospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (325 aa)
OEOE_1149Cell division protein FtsI/penicillin-binding protein 2. (712 aa)
OEOE_1150Cell division protein FtsL. (124 aa)
rsmHSAM-dependent methyltransferase for cell envelope biogenesis; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (314 aa)
mraZHypothetical protein, MraZ; Belongs to the MraZ family. (143 aa)
OEOE_1153Hypothetical protein. (104 aa)
OEOE_1154DNA segregation ATPase FtsK; Belongs to the FtsK/SpoIIIE/SftA family. (787 aa)
OEOE_1155Predicted rRNA methylase (SpoU class); Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (168 aa)
OEOE_1156Predicted permease. (382 aa)
OEOE_1158Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (299 aa)
OEOE_1160Oligopeptidase F, Metallo peptidase, MEROPS family M03B. (603 aa)
OEOE_1161Competence protein. (362 aa)
OEOE_1162Negative regulator of genetic competence, sporulation and motility. (241 aa)
OEOE_1163Hypothetical protein. (145 aa)
OEOE_1164Hypothetical protein; Belongs to the UPF0473 family. (114 aa)
OEOE_1165RNase H-like ribonuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (144 aa)
OEOE_1166Hypothetical protein; Belongs to the UPF0297 family. (90 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity); Belongs to the class-II aminoacyl-tRNA synthetase family. (885 aa)
OEOE_1192Recombination protein MgsA. (445 aa)
OEOE_1199Muramidase with LysM repeats. (390 aa)
OEOE_1200Hypothetical protein. (208 aa)
OEOE_1244Cell elongation-specific peptidoglycan D,D-transpeptidase. (688 aa)
OEOE_1247Muramidase (flagellum-specific). (291 aa)
OEOE_1261Cell division-specific peptidoglycan biosynthesis regulator FtsW; Belongs to the SEDS family. (416 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (435 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (219 aa)
OEOE_1273Predicted ABC-type exoprotein transport system, permease component. (352 aa)
OEOE_1274ABC-type multidrug transport system, ATPase component. (244 aa)
OEOE_1275Diadenosine tetraphosphate (Ap4A) hydrolase related HIT family hydrolase. (139 aa)
OEOE_1276Hypothetical protein. (92 aa)
OEOE_1277Parvulin-like peptidyl-prolyl isomerase. (342 aa)
OEOE_1281BS_ysoA related protein with TPR repeats. (319 aa)
ezrANegative regulator of septation ring formation; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (567 aa)
OEOE_1428tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (330 aa)
OEOE_1429Cell wall-associated hydrolase. (415 aa)
OEOE_1430Cell wall-associated hydrolase with LysM domains. (397 aa)
ungUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (226 aa)
OEOE_1440Superfamily I DNA and RNA helicase. (762 aa)
OEOE_1442Peptidoglycan interpeptide bridge formation enzyme. (422 aa)
OEOE_1443Sortase (surface protein transpeptidase). (284 aa)
OEOE_1444Peptidoglycan interpeptide bridge formation enzyme. (339 aa)
OEOE_1446Auxin efflux carrier (AEC) family permease. (315 aa)
OEOE_1561D-alanyl-D-alanine carboxypeptidase. (272 aa)
OEOE_1599UDP-N-acetylmuramyl tripeptide synthase. (445 aa)
OEOE_1600Predicted glutamine amidotransferase. (244 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (461 aa)
OEOE_1654Hypothetical protein. (102 aa)
OEOE_1655Hypothetical protein. (345 aa)
dacAHypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (297 aa)
OEOE_1657Sodium/proton antiporter, CPA1 family; TC 2.A.36. (705 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (259 aa)
OEOE_1659Exonuclease III. (273 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (428 aa)
rpoEDNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. (195 aa)
OEOE_1789Hypothetical protein. (146 aa)
OEOE_1790HD superfamily phosphohydrolase. (430 aa)
Your Current Organism:
Oenococcus oeni
NCBI taxonomy Id: 203123
Other names: O. oeni PSU-1, Oenococcus oeni PSU-1, Oenococcus oeni str. PSU-1, Oenococcus oeni strain PSU-1
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