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ctpA ctpA TWT_034 TWT_034 fepG fepG fepD fepD TWT_086 TWT_086 secA secA TWT_180 TWT_180 qacA qacA bioY bioY ctaC ctaC ctaD ctaD TWT_245 TWT_245 ctaE ctaE qcrC qcrC qcrB qcrB secD secD secF secF secG secG tatC tatC TWT_329 TWT_329 phoT phoT pstA pstA pstC pstC TWT_420 TWT_420 atpD atpD atpG atpG atpA atpA atpH atpH atpF atpF atpE atpE atpB atpB mgtE mgtE TWT_557 TWT_557 TWT_559 TWT_559 TWT_560 TWT_560 TWT_600 TWT_600 TWT_601 TWT_601 TWT_603 TWT_603 TWT_645 TWT_645 TWT_684 TWT_684 secE secE nhaA nhaA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ctpACation-transporting ATPase. (716 aa)
TWT_034ABC transporter ATP-binding protein. (268 aa)
fepGIron ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (395 aa)
fepDIron ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (321 aa)
TWT_086Putative drug efflux protein. (377 aa)
secAPreprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (847 aa)
TWT_180Unknown. (488 aa)
qacAMultidrug efflux protein. (390 aa)
bioYBiotin synthesis BioY protein. (197 aa)
ctaCCytochrome c oxidase subunit II. (290 aa)
ctaDCytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (543 aa)
TWT_245Unknown. (139 aa)
ctaECytochrome c oxidase subunit III. (207 aa)
qcrCUbiquinol-cytochrome c reductase cytochrome c subunit. (288 aa)
qcrBUbiquinol-cytochrome c reductase cytochrome b subunit. (536 aa)
secDPreprotein translocase SecD subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (559 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (322 aa)
secGPreprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (98 aa)
tatCTwin-arginine translocase TatC component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (255 aa)
TWT_329Sugar ABC transporter permease protein (L-arabinose/D-xylose); Belongs to the binding-protein-dependent transport system permease family. (410 aa)
phoTPhosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (269 aa)
pstAPhosphate transport system permease protein. (297 aa)
pstCPhosphate transport system permease protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (299 aa)
TWT_420Cation efflux protein. (312 aa)
atpDATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (477 aa)
atpGATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (336 aa)
atpAATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (554 aa)
atpHATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (327 aa)
atpFATP synthase B chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (172 aa)
atpEATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (75 aa)
atpBATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (271 aa)
mgtEMg2+ transporter. (421 aa)
TWT_557Branched-chain amino acid ABC transporter ATP-binding protein. (233 aa)
TWT_559Branched-chain amino acid ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. (364 aa)
TWT_560Branched-chain amino acid ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family. (334 aa)
TWT_600ABC transporter ATP-binding protein. (623 aa)
TWT_601ABC transporter ATP-binding protein. (589 aa)
TWT_603Unknown. (364 aa)
TWT_645MFS family transporter (D-galactonate). (439 aa)
TWT_684Putative efflux protein. (408 aa)
secEUnknown; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (80 aa)
nhaASodium-proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (385 aa)
Your Current Organism:
Tropheryma whipplei
NCBI taxonomy Id: 203267
Other names: T. whipplei str. Twist, Tropheryma whipplei Twist, Tropheryma whipplei str. Twist, Tropheryma whipplei strain Twist
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