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ogt ogt truA truA BFO_0041 BFO_0041 BFO_0947 BFO_0947 BFO_0175 BFO_0175 BFO_0176 BFO_0176 serC serC BFO_0219 BFO_0219 BFO_0252 BFO_0252 etfA_1 etfA_1 BFO_0303 BFO_0303 BFO_0413 BFO_0413 BFO_0441 BFO_0441 BFO_0556 BFO_0556 BFO_0558 BFO_0558 nadD nadD BFO_0642 BFO_0642 BFO_0676 BFO_0676 BFO_0682 BFO_0682 BFO_0725 BFO_0725 msrB msrB leuA leuA BFO_0823 BFO_0823 BFO_0895 BFO_0895 ybeY ybeY BFO_3293 BFO_3293 BFO_3273 BFO_3273 BFO_3238 BFO_3238 BFO_3201 BFO_3201 BFO_3175 BFO_3175 BFO_3171 BFO_3171 BFO_3153 BFO_3153 ilvE ilvE BFO_3058 BFO_3058 BFO_3046 BFO_3046 BFO_2966 BFO_2966 BFO_2955 BFO_2955 BFO_2938 BFO_2938 BFO_2884 BFO_2884 ispE ispE argB argB BFO_2803 BFO_2803 BFO_2802 BFO_2802 BFO_2784 BFO_2784 BFO_2777 BFO_2777 BFO_2744 BFO_2744 BFO_2739 BFO_2739 BFO_2738 BFO_2738 BFO_2737 BFO_2737 BFO_2731 BFO_2731 BFO_2658 BFO_2658 BFO_2656 BFO_2656 BFO_2645 BFO_2645 BFO_2634 BFO_2634 BFO_2633 BFO_2633 BFO_2596 BFO_2596 BFO_2570 BFO_2570 BFO_2524 BFO_2524 BFO_2290 BFO_2290 BFO_2256 BFO_2256 BFO_2248 BFO_2248 BFO_2208 BFO_2208 adk adk rpsB rpsB BFO_2075 BFO_2075 rprY rprY nadC nadC nfo nfo BFO_1951 BFO_1951 rplA rplA BFO_1923 BFO_1923 BFO_1914 BFO_1914 BFO_1902 BFO_1902 tadA tadA BFO_1851 BFO_1851 BFO_1849 BFO_1849 BFO_1815 BFO_1815 argC argC folK folK nth nth BFO_1693 BFO_1693 BFO_1683 BFO_1683 BFO_1682 BFO_1682 sufD sufD sufC sufC sufB sufB aspC aspC BFO_1659 BFO_1659 ribF ribF BFO_1609 BFO_1609 BFO_1591 BFO_1591 rpsD rpsD rpsM rpsM rplP rplP rpsL rpsL BFO_1537 BFO_1537 BFO_1505 BFO_1505 etfA_2 etfA_2 bcd bcd cat cat pyk pyk ribD ribD ychF ychF BFO_1406 BFO_1406 BFO_1398 BFO_1398 BFO_1396 BFO_1396 lpxA lpxA BFO_1323 BFO_1323 BFO_1238 BFO_1238 purD purD BFO_1182 BFO_1182 BFO_1166 BFO_1166 BFO_1155 BFO_1155 rnz rnz BFO_1096 BFO_1096 BFO_1074 BFO_1074 BFO_1032 BFO_1032 BFO_1016 BFO_1016 BFO_1007 BFO_1007 sbcD sbcD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ogtmethylated-DNA--[protein]-cysteine S-methyltransferase; Identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589. (111 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (252 aa)
BFO_0041Putative membrane protein. (390 aa)
BFO_0947AMP-binding enzyme; Identified by match to protein family HMM PF00501. (635 aa)
BFO_0175AMP-binding enzyme; Identified by match to protein family HMM PF00501. (557 aa)
BFO_0176Cupin domain protein; Identified by match to protein family HMM PF01381; match to protein family HMM PF07883. (184 aa)
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (387 aa)
BFO_0219Hypothetical protein. (118 aa)
BFO_0252acyl-CoA dehydrogenase, C-terminal domain protein; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028. (568 aa)
etfA_1Electron transfer flavoprotein subunit alpha; Identified by match to protein family HMM PF00766; match to protein family HMM PF01012. (339 aa)
BFO_0303Metallo-beta-lactamase domain protein; Identified by match to protein family HMM PF00753. (268 aa)
BFO_0413Succinate CoA transferase; Identified by match to protein family HMM PF02550; match to protein family HMM TIGR03458. (497 aa)
BFO_0441Peptidase, M48 family; Identified by match to protein family HMM PF01435. (269 aa)
BFO_0556Putative V-type sodium ATPase, B subunit; Identified by match to protein family HMM PF00006; match to protein family HMM PF02874. (441 aa)
BFO_0558Hypothetical protein. (289 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (201 aa)
BFO_0642AMP-binding enzyme; Identified by match to protein family HMM PF00501. (560 aa)
BFO_0676Identified by match to protein family HMM PF06824. (489 aa)
BFO_0682Hypothetical protein. (1241 aa)
BFO_0725Arylsulfatase; Identified by match to protein family HMM PF00884. (514 aa)
msrBmethionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (341 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (495 aa)
BFO_0823Identified by match to protein family HMM PF00682; match to protein family HMM PF08502; Belongs to the alpha-IPM synthase/homocitrate synthase family. (526 aa)
BFO_0895Putative transcriptional regulatory protein RprY; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. (227 aa)
ybeYTranslation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (141 aa)
BFO_3293FAH family protein; Identified by match to protein family HMM PF01557. (203 aa)
BFO_3273ATPase, AAA family; Identified by match to protein family HMM PF00004. (317 aa)
BFO_3238Identified by match to protein family HMM PF06966. (190 aa)
BFO_3201Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. (383 aa)
BFO_3175AMP-binding enzyme; Identified by match to protein family HMM PF00501. (551 aa)
BFO_3171Peptidase, M28 family; Identified by match to protein family HMM PF01546; match to protein family HMM PF04389. (336 aa)
BFO_3153Homoserine dehydrogenase; Identified by match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. (812 aa)
ilvEBranched-chain-amino-acid transaminase; Identified by match to protein family HMM PF01063; match to protein family HMM TIGR01123. (339 aa)
BFO_3058O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01053; match to protein family HMM TIGR01326. (426 aa)
BFO_3046RNAse H domain protein, YqgF family; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (140 aa)
BFO_2966O-Glycosyl hydrolase family 30; Identified by match to protein family HMM PF02055; Belongs to the glycosyl hydrolase 30 family. (486 aa)
BFO_2955Aminopeptidase P, N-terminal domain protein; Identified by match to protein family HMM PF00557; match to protein family HMM PF05195. (459 aa)
BFO_2938Identified by match to protein family HMM PF03641; match to protein family HMM TIGR00730; Belongs to the LOG family. (178 aa)
BFO_2884ATPase, AAA family; Identified by match to protein family HMM PF07726; match to protein family HMM PF07728. (331 aa)
ispE4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (267 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (255 aa)
BFO_2803O-Glycosyl hydrolase family 30; Identified by match to protein family HMM PF02055; Belongs to the glycosyl hydrolase 30 family. (493 aa)
BFO_2802Identified by match to protein family HMM PF07980. (558 aa)
BFO_2784Hypothetical protein. (633 aa)
BFO_2777Arylsulfatase; Identified by match to protein family HMM PF00884. (526 aa)
BFO_2744Identified by match to protein family HMM PF07980. (519 aa)
BFO_2739Hypothetical protein. (194 aa)
BFO_2738Proline dehydrogenase; Identified by match to protein family HMM PF01619. (389 aa)
BFO_2737Alpha-L-fucosidase; Identified by match to protein family HMM PF01120. (446 aa)
BFO_2731Peptidase dimerization domain protein; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687. (452 aa)
BFO_2658Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. (392 aa)
BFO_2656Hypothetical protein. (94 aa)
BFO_2645NAD dependent epimerase/dehydratase family protein; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993. (347 aa)
BFO_2634Identified by match to protein family HMM PF07980. (562 aa)
BFO_2633Cupin domain protein; Identified by match to protein family HMM PF07883. (109 aa)
BFO_2596Hypothetical protein. (367 aa)
BFO_2570Putative peroxiredoxin bcp; Identified by match to protein family HMM PF00578; match to protein family HMM PF08534. (151 aa)
BFO_2524Cation diffusion facilitator family transporter; Identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (301 aa)
BFO_2290Arylsulfatase; Identified by match to protein family HMM PF00884. (516 aa)
BFO_2256Peptidase C1-like family; Identified by match to protein family HMM PF03051; Belongs to the peptidase C1 family. (389 aa)
BFO_2248NAD dependent epimerase/dehydratase family protein; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993. (315 aa)
BFO_2208Glycosyl hydrolase family 20, catalytic domain protein; Identified by match to protein family HMM PF00728. (665 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (192 aa)
rpsBRibosomal protein S2; Identified by match to protein family HMM PF00318; match to protein family HMM TIGR01011; Belongs to the universal ribosomal protein uS2 family. (286 aa)
BFO_2075CobN/magnesium chelatase domain protein; Identified by match to protein family HMM PF02514. (1461 aa)
rprYTranscriptional regulatory protein RprY; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. (241 aa)
nadCNicotinate-nucleotide diphosphorylase (carboxylating); Identified by match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; Belongs to the NadC/ModD family. (282 aa)
nfoApurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (277 aa)
BFO_1951Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543. (397 aa)
rplARibosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (231 aa)
BFO_1923Glycosyl hydrolase family 20, catalytic domain protein; Identified by match to protein family HMM PF00728; match to protein family HMM PF02838; match to protein family HMM PF07691. (777 aa)
BFO_19145'-nucleotidase, C-terminal domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (479 aa)
BFO_1902Putative CDP-diacylglycerol-serine O-phosphatidyltransferase; Identified by match to protein family HMM PF01066; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (247 aa)
tadACytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
BFO_1851Hypothetical protein. (406 aa)
BFO_1849Recombination factor protein RarA; Identified by match to protein family HMM PF00004. (425 aa)
BFO_1815Hypothetical protein. (216 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (324 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. (159 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (217 aa)
BFO_1693Peptidase, M28 family; Identified by match to protein family HMM PF04389. (333 aa)
BFO_1683Oxidoreductase, short chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106; match to protein family HMM PF08659. (260 aa)
BFO_1682Prephenate dehydratase; Identified by match to protein family HMM PF00800. (280 aa)
sufDFeS assembly protein SufD; Identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981. (458 aa)
sufCFeS assembly ATPase SufC; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978. (252 aa)
sufBFeS assembly protein SufB; Identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980. (485 aa)
aspCAspartate transaminase; Identified by match to protein family HMM PF00155. (397 aa)
BFO_1659Peptidase, S9A/B/C family, catalytic domain protein; Identified by match to protein family HMM PF00326; match to protein family HMM PF00930; match to protein family HMM PF02129. (722 aa)
ribFRiboflavin biosynthesis protein RibF; Identified by match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; Belongs to the ribF family. (324 aa)
BFO_1609Hypothetical protein. (187 aa)
BFO_1591Phospholipase, patatin family; Identified by match to protein family HMM PF01734. (278 aa)
rpsDRibosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (201 aa)
rpsM30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (126 aa)
rplPRibosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (144 aa)
rpsLRibosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (129 aa)
BFO_1537Putative cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (164 aa)
BFO_1505Identified by match to protein family HMM PF00076. (81 aa)
etfA_2Electron transfer flavoprotein subunit alpha; Identified by match to protein family HMM PF00766; match to protein family HMM PF01012. (335 aa)
bcdbutyryl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028. (382 aa)
cat4-hydroxybutyrate coenzyme A transferase; Identified by match to protein family HMM PF02550. (430 aa)
pykPyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (481 aa)
ribDRiboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (357 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (367 aa)
BFO_1406Identified by match to protein family HMM PF07980. (514 aa)
BFO_1398Identified by match to protein family HMM PF07980. (521 aa)
BFO_1396Putative membrane protein. (375 aa)
lpxAacyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (260 aa)
BFO_1323Putative gliding motility-associated lipoprotein GldK; Identified by match to protein family HMM PF03781. (480 aa)
BFO_1238Hypothetical protein. (137 aa)
purDPhosphoribosylamine--glycine ligase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02655; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM TIGR00877; Belongs to the GARS family. (424 aa)
BFO_1182F5/8 type C domain protein; Identified by match to protein family HMM PF00754. (684 aa)
BFO_1166ATPase, AAA family; Identified by match to protein family HMM PF07726; match to protein family HMM PF07728. (323 aa)
BFO_1155Na/Pi-cotransporter II-like protein; Identified by match to protein family HMM PF02690; match to protein family HMM TIGR00704. (601 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (310 aa)
BFO_10965'-nucleotidase, C-terminal domain protein; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. (478 aa)
BFO_1074NAD dependent epimerase/dehydratase family protein; Identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993. (325 aa)
BFO_1032Histidine triad domain protein; Identified by match to protein family HMM PF01230. (133 aa)
BFO_1016Secondary thiamine-phosphate synthase enzyme; Identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149. (138 aa)
BFO_1007Peptidase, S9A/B/C family, catalytic domain protein; Identified by match to protein family HMM PF00326; match to protein family HMM PF00930. (725 aa)
sbcDExonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (402 aa)
Your Current Organism:
Tannerella forsythia
NCBI taxonomy Id: 203275
Other names: T. forsythia 92A2, Tannerella forsythia 92A2
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