STRINGSTRING
rpsG rpsG KIQ12811.1 KIQ12811.1 pdxS pdxS KIQ12916.1 KIQ12916.1 KIQ12952.1 KIQ12952.1 KIQ12384.1 KIQ12384.1 KIQ12387.1 KIQ12387.1 KIQ12481.1 KIQ12481.1 KIQ12420.1 KIQ12420.1 KIQ12444.1 KIQ12444.1 rpsI rpsI rplM rplM rplQ rplQ rpsK rpsK rpmD rpmD rpsE rpsE rplR rplR rpsH rpsH rplE rplE rplX rplX rplN rplN rpsQ rpsQ rpmC rpmC rpsC rpsC rplB rplB rplW rplW rplC rplC rpsJ rpsJ KIQ11850.1 KIQ11850.1 KIQ11925.1 KIQ11925.1 KIQ11935.1 KIQ11935.1 rplY rplY KIQ11327.1 KIQ11327.1 KIQ11373.1 KIQ11373.1 RecQ RecQ CcsB CcsB KIQ10416.1 KIQ10416.1 KIQ10457.1 KIQ10457.1 RpmJ RpmJ KIQ10496.1 KIQ10496.1 KIQ10331.1 KIQ10331.1 rpmB rpmB rpmG rpmG rpsN rpsN KIQ10264.1 KIQ10264.1 KIQ10035.1 KIQ10035.1 KIQ09918.1 KIQ09918.1 rpsO rpsO obgE obgE rplU rplU KIQ10030.1 KIQ10030.1 KIQ09830.1 KIQ09830.1 hpf hpf topA topA KIQ09295.1 KIQ09295.1 KIQ09296.1 KIQ09296.1 KIQ09299.1 KIQ09299.1 KIQ08255.1 KIQ08255.1 nnrE nnrE KIQ07894.1 KIQ07894.1 KIQ07635.1 KIQ07635.1 KIQ07572.1 KIQ07572.1 rpsB rpsB rpsP rpsP smc smc rpmF rpmF KIQ06646.1 KIQ06646.1 KIQ06197.1 KIQ06197.1 KIQ05764.1 KIQ05764.1 DnaB DnaB rpsR rpsR rpsF rpsF KIQ05776.1 KIQ05776.1 KIQ05777.1 KIQ05777.1 rpmH rpmH recF recF gyrB gyrB gyrA gyrA KIQ05793.1 KIQ05793.1 rplT rplT rpmI rpmI dnaG dnaG recO recO rpsT rpsT KIQ04518.1 KIQ04518.1 KIQ04519.1 KIQ04519.1 KIQ03606.1 KIQ03606.1 KIQ03500.1 KIQ03500.1 KIQ03518.1 KIQ03518.1 KIQ02498.1 KIQ02498.1 KIQ02135.1 KIQ02135.1 KIQ01684.1 KIQ01684.1 KIQ01689.1 KIQ01689.1 RecN RecN rpmE2 rpmE2 rpsA rpsA cutC cutC rplJ rplJ rplL rplL recR recR KIQ00046.1 KIQ00046.1 KIP99505.1 KIP99505.1 KIP98670.1 KIP98670.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
KIQ12811.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (174 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (306 aa)
KIQ12916.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
KIQ12952.1RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (812 aa)
KIQ12384.1ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
KIQ12387.1ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
KIQ12481.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (691 aa)
KIQ12420.1Chromosome partitioning protein ParA; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
KIQ12444.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
rpsI30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (161 aa)
rplM50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (148 aa)
rplQ50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
rpsK30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (132 aa)
rpmD50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology. (62 aa)
rpsE30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (282 aa)
rplR50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (124 aa)
rpsH30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (196 aa)
rplX50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (119 aa)
rplN50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (94 aa)
rpmC50S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family. (106 aa)
rpsC30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (270 aa)
rplB50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (279 aa)
rplW50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (99 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (218 aa)
rpsJ30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
KIQ11850.1DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
KIQ11925.1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
KIQ11935.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
rplY50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (207 aa)
KIQ11327.1Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
KIQ11373.1DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (296 aa)
RecQATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (613 aa)
CcsBCytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
KIQ10416.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
KIQ10457.1Phosphoglycerate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
RpmJ50S ribosomal protein L36; Derived by automated computational analysis using gene prediction method: Protein Homology. (40 aa)
KIQ10496.1Carbohydrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
KIQ10331.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
rpmB50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL28 family. (78 aa)
rpmG50S ribosomal protein L33; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL33 family. (56 aa)
rpsN30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
KIQ10264.1Integration host factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial histone-like protein family. (95 aa)
KIQ10035.1ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (699 aa)
KIQ09918.1Chromosome partitioning protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
rpsO30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa)
obgEGTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (525 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa)
KIQ10030.1N-acetylneuraminate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
KIQ09830.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (231 aa)
hpfRNA polymerase subunit sigma-54; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (238 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (938 aa)
KIQ09295.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
KIQ09296.1Pilus assembly protein CpaF; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
KIQ09299.1Metallophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
KIQ08255.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SOS response-associated peptidase family. (243 aa)
nnrEHypothetical protein; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. (255 aa)
KIQ07894.1Lipopolysaccharide kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
KIQ07635.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
KIQ07572.1ADP-ribosylglycohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
rpsB30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family. (308 aa)
rpsP30S ribosomal protein S16; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS16 family. (137 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1258 aa)
rpmF50S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL32 family. (67 aa)
KIQ06646.1ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
KIQ06197.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
KIQ05764.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (930 aa)
DnaBHelicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (454 aa)
rpsR30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (85 aa)
rpsF30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (131 aa)
KIQ05776.1Chromosome partitioning protein ParB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ParB family. (322 aa)
KIQ05777.1Chromosome partitioning protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
rpmH50S ribosomal protein L34; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL34 family. (45 aa)
recFRecombinase RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (444 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (667 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (885 aa)
KIQ05793.1Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (606 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (127 aa)
rpmI50S ribosomal protein L35; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL35 family. (64 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (638 aa)
recODNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. (282 aa)
rpsT30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (86 aa)
KIQ04518.1ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
KIQ04519.1ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
KIQ03606.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (660 aa)
KIQ03500.1Ribulose 5-phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
KIQ03518.1Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
KIQ02498.1Carbohydrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
KIQ02135.1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
KIQ01684.1DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (856 aa)
KIQ01689.1Molecular chaperone DnaK; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
RecNDNA recombination protein RecN; May be involved in recombinational repair of damaged DNA. (564 aa)
rpmE2RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may b [...] (82 aa)
rpsA30S ribosomal protein S1; In Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
cutCCopper homeostasis protein CutC; Participates in the control of copper homeostasis. Belongs to the CutC family. (245 aa)
rplJ50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (171 aa)
rplL50S ribosomal protein L7; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (126 aa)
recRRecombinase RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (199 aa)
KIQ00046.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
KIP99505.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (60 aa)
KIP98670.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (490 aa)
Your Current Organism:
Curtobacterium flaccumfaciens
NCBI taxonomy Id: 2035
Other names: Bacterium flaccumfaciens, Bacterium poinsettiae, C. flaccumfaciens, CIP 107085, Corynebacterium betae, Corynebacterium flaccumfaciens, Corynebacterium flaccumfaciens subsp. betae, Corynebacterium flaccumfaciens subsp. flaccumfaciens, Corynebacterium flaccumfaciens subsp. oortii, Corynebacterium flaccumfaciens subsp. poinsettiae, Corynebacterium oortii, Curtibacterium flaccumfaciens, ICMP 2584, JCM 9670, LMG 3645, LMG:3645, Phytomonas flaccumfaciens, Phytomonas poinsettiae, Pseudomonas flaccumfaciens
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