(63 nodes) Mixed, incl. Valine, leucine and isoleucine degradation, and enoyl-CoA hydratase activity network (Pimelobacter simplex)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	paaG_2	Enoyl-CoA hydratase. (264 aa)
	AIY15624.1	Long-chain-fatty-acid--CoA ligase. (555 aa)
	AIY15625.1	Uncharacterized protein. (243 aa)
	AIY15626.1	Enoyl-CoA hydratase. (260 aa)
	AIY15629.1	acyl-CoA dehydrogenase. (342 aa)
	AIY15630.1	acyl-CoA dehydrogenase. (392 aa)
	AIY15631.2	acyl-CoA synthetase. (512 aa)
	AIY15632.1	3-ketoacyl-[acyl-carrier protein] reductase fabG. (251 aa)
	AIY15633.1	3-ketoacyl-CoA thiolase, acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	AIY15659.1	3-ketoacyl-CoA thiolase, acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
	fadB	Short chain enoyl-CoA hydratase [isoleucine degradation]/3-hydroxyacyl-CoA dehydrogenase. (728 aa)
	AIY15866.1	NADPH dependent 2,4-dienoyl-CoA reductase. (651 aa)
	AIY15867.2	enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
	AIY15877.1	Short-chain dehydrogenase. (249 aa)
	AIY15878.1	Acyl dehydratase. (154 aa)
	paaG_1	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (272 aa)
	fadE2	Butyryl-CoA dehydrogenase. (415 aa)
	AIY15996.1	Enoyl-CoA hydratase. (258 aa)
	AIY16020.1	Acyl-coenzyme A oxidase 1, peroxisomal. (657 aa)
	paaG_3	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
	AIY16611.1	Long-chain-fatty-acid--CoA ligase. (501 aa)
	AIY16612.1	Transcriptional regulator, TetR family. (194 aa)
	AIY16637.1	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa)
	fabG_7	3-ketoacyl-(acyl-carrier-protein) reductase. (252 aa)
	AIY16672.2	acyl-CoA dehydrogenase. (703 aa)
	AIY16673.1	ABC transporter ATP-binding protein. (547 aa)
	AIY16783.1	Glutaryl-CoA dehydrogenase. (388 aa)
	AIY16797.1	3-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
	AIY16832.1	Methylsuccinyl-CoA dehydrogenase. (399 aa)
	AIY19823.2	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
	AIY17083.1	3-hydroxybutyryl-CoA dehydrogenase. (390 aa)
	AIY17088.1	Crotonyl-CoA carboxylase/reductase, ethylmalonyl-CoA producing. (445 aa)
	AIY17091.1	3-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
	atoB_1	3-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa)
	AIY17443.2	Butyryl-CoA dehydrogenase. (379 aa)
	AIY17619.1	enoyl-CoA hydratase echA19. (270 aa)
	AIY17642.2	acetyl-CoA-acetyltransferase, Mycobacterial subgroup fadA5; Belongs to the thiolase-like superfamily. Thiolase family. (383 aa)
	AIY17646.1	enoyl-CoA hydratase echA20. (253 aa)
	AIY17925.2	3-methylmercaptopropionyl-CoA dehydrogenase (DmdC). (243 aa)
	AIY17949.1	Butyryl-CoA dehydrogenase. (403 aa)
	AIY18171.1	Electron transfer flavoprotein, alpha subunit. (320 aa)
	AIY18172.2	Electron transfer flavoprotein, beta subunit. (257 aa)
	AIY20015.2	Hypothetical protein. (134 aa)
	AIY18173.1	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (261 aa)
	AIY18355.1	Acyl dehydratase. (150 aa)
	AIY18464.1	Butyryl-CoA dehydrogenase. (389 aa)
	AIY18489.1	Isovaleryl-CoA dehydrogenase. (399 aa)
	AIY18552.1	Acyl dehydratase. (150 aa)
	AIY18811.1	Butyryl-CoA dehydrogenase. (375 aa)
	AIY18812.2	Butyryl-CoA dehydrogenase. (389 aa)
	AIY18814.1	3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation]. (252 aa)
	AIY18815.1	enoyl-CoA hydratase echA1; Belongs to the enoyl-CoA hydratase/isomerase family. (269 aa)
	paaH	3-hydroxybutyryl-CoA dehydrogenase. (284 aa)
	AIY19209.1	Butyryl-CoA dehydrogenase. (381 aa)
	paaG_5	enoyl-CoA hydratase. (291 aa)
	atoB_4	acetyl-CoA acetyltransferase, Mycobacterial subgroup fadA3; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)
	AIY20186.2	Enoyl-CoA hydratase. (208 aa)
	hmgL	Hydroxymethylglutaryl-CoA lyase. (315 aa)
	AIY19383.1	Acyl-CoA dehydrogenase. (543 aa)
	AIY19396.1	FadB4. (320 aa)
	scoB	Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B. (209 aa)
	AIY19555.1	Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A. (254 aa)
	AIY20228.2	3-hydroxyisobutyryl-CoA hydrolase. (338 aa)

Your Current Organism:

Pimelobacter simplex

NCBI taxonomy Id: 2045
Other names: ATCC 6946, Arthrobacter simplex, CCUG 23611, CIP 82.106, Corynebacterium simplex, DSM 20130, HAMBI 90, IFO 12069, KCTC 9106, LMG 16261, LMG:16261, NBRC 12069, NCIB 8929, NCIB:8929, Nocardioides simplex, P. simplex

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIY15624.1	AIY15625.1	KR76_00430	KR76_00435	Long-chain-fatty-acid--CoA ligase.	Uncharacterized protein.	0.774
AIY15624.1	AIY15626.1	KR76_00430	KR76_00440	Long-chain-fatty-acid--CoA ligase.	Enoyl-CoA hydratase.	0.831
AIY15624.1	fadB	KR76_00430	KR76_00685	Long-chain-fatty-acid--CoA ligase.	Short chain enoyl-CoA hydratase [isoleucine degradation]/3-hydroxyacyl-CoA dehydrogenase.	0.492
AIY15624.1	paaG_2	KR76_00430	KR76_00425	Long-chain-fatty-acid--CoA ligase.	Enoyl-CoA hydratase.	0.652
AIY15625.1	AIY15624.1	KR76_00435	KR76_00430	Uncharacterized protein.	Long-chain-fatty-acid--CoA ligase.	0.774
AIY15625.1	AIY15626.1	KR76_00435	KR76_00440	Uncharacterized protein.	Enoyl-CoA hydratase.	0.778
AIY15625.1	paaG_2	KR76_00435	KR76_00425	Uncharacterized protein.	Enoyl-CoA hydratase.	0.541
AIY15626.1	AIY15624.1	KR76_00440	KR76_00430	Enoyl-CoA hydratase.	Long-chain-fatty-acid--CoA ligase.	0.831
AIY15626.1	AIY15625.1	KR76_00440	KR76_00435	Enoyl-CoA hydratase.	Uncharacterized protein.	0.778
AIY15626.1	AIY15629.1	KR76_00440	KR76_00475	Enoyl-CoA hydratase.	acyl-CoA dehydrogenase.	0.537
AIY15626.1	AIY15630.1	KR76_00440	KR76_00480	Enoyl-CoA hydratase.	acyl-CoA dehydrogenase.	0.537
AIY15626.1	AIY15633.1	KR76_00440	KR76_00495	Enoyl-CoA hydratase.	3-ketoacyl-CoA thiolase, acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.638
AIY15626.1	AIY15659.1	KR76_00440	KR76_00680	Enoyl-CoA hydratase.	3-ketoacyl-CoA thiolase, acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.638
AIY15626.1	AIY15878.1	KR76_00440	KR76_02175	Enoyl-CoA hydratase.	Acyl dehydratase.	0.413
AIY15626.1	AIY16020.1	KR76_00440	KR76_03245	Enoyl-CoA hydratase.	Acyl-coenzyme A oxidase 1, peroxisomal.	0.537
AIY15626.1	AIY16672.2	KR76_00440	KR76_07645	Enoyl-CoA hydratase.	acyl-CoA dehydrogenase.	0.537
AIY15626.1	AIY16783.1	KR76_00440	KR76_08380	Enoyl-CoA hydratase.	Glutaryl-CoA dehydrogenase.	0.537
AIY15626.1	AIY16797.1	KR76_00440	KR76_08475	Enoyl-CoA hydratase.	3-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.638
AIY15626.1	AIY16832.1	KR76_00440	KR76_08735	Enoyl-CoA hydratase.	Methylsuccinyl-CoA dehydrogenase.	0.537
AIY15626.1	AIY17083.1	KR76_00440	KR76_10590	Enoyl-CoA hydratase.	3-hydroxybutyryl-CoA dehydrogenase.	0.970

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