STRINGSTRING
AJR18535.1 AJR18535.1 ansB ansB AIY19657.2 AIY19657.2 AIY19658.1 AIY19658.1 AJR18041.1 AJR18041.1 cobB_2 cobB_2 AJR18081.1 AJR18081.1 AIY19686.2 AIY19686.2 tilS tilS AIY16023.1 AIY16023.1 ftsH ftsH folE folE AIY19688.1 AIY19688.1 folP folP folB folB AIY16040.1 AIY16040.1 AIY16041.2 AIY16041.2 AIY16042.2 AIY16042.2 AIY16051.1 AIY16051.1 AIY16052.1 AIY16052.1 panC panC panD panD AIY16054.2 AIY16054.2 AIY19690.2 AIY19690.2 coaX coaX phoD_1 phoD_1 AIY16487.2 AIY16487.2 coaA coaA AIY16674.1 AIY16674.1 AIY16818.1 AIY16818.1 AIY16906.1 AIY16906.1 nadA nadA coaE coaE AIY17686.2 AIY17686.2 AIY17834.2 AIY17834.2 aspA aspA nadE nadE panB panB AIY18036.1 AIY18036.1 AIY18037.2 AIY18037.2 phoD_2 phoD_2 nadD nadD coaD coaD AIY18801.1 AIY18801.1 AIY18852.1 AIY18852.1 AIY20171.2 AIY20171.2 pntA pntA pntB pntB AIY19284.1 AIY19284.1 AIY19495.2 AIY19495.2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJR18535.1Hypothetical protein. (54 aa)
ansBL-asparaginase. (329 aa)
AIY19657.22-hydroxymuconic semialdehyde hydrolase. (279 aa)
AIY19658.1Arylmalonate decarboxylase. (237 aa)
AJR18041.1Transcriptional regulator, TetR family. (238 aa)
cobB_2NAD-dependent protein deacetylase of SIR2 family; Belongs to the sirtuin family. Class III subfamily. (230 aa)
AJR18081.1D-alanyl-D-alanine carboxypeptidase. (489 aa)
AIY19686.2Putative hydrolase. (349 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (327 aa)
AIY16023.1Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (183 aa)
ftsHCell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (675 aa)
folEGTP cyclohydrolase I type 1. (206 aa)
AIY19688.1Methyltransferase. (266 aa)
folPDihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (291 aa)
folBDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (135 aa)
AIY16040.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (189 aa)
AIY16041.2Secreted protein. (150 aa)
AIY16042.2Putative multidomain membrane protein. (180 aa)
AIY16051.1Hypothetical protein. (206 aa)
AIY16052.1Ketopantoate reductase PanG. (303 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (292 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (139 aa)
AIY16054.2L-aspartate oxidase. (241 aa)
AIY19690.2Quinolinate phosphoribosyltransferase [decarboxylating]; Belongs to the NadC/ModD family. (304 aa)
coaXPantothenate kinase type III, CoaX-like; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (261 aa)
phoD_1Alkaline phosphatase. (558 aa)
AIY16487.2L-asparaginase. (332 aa)
coaAPantothenate kinase. (329 aa)
AIY16674.1Putative alkaline phosphatase. (562 aa)
AIY16818.1Dihydrofolate synthase, Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (450 aa)
AIY16906.1NADH pyrophosphatase. (303 aa)
nadAQuinolinate synthetase nadA; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (391 aa)
coaEDephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (199 aa)
AIY17686.2Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (404 aa)
AIY17834.2Molybdopterin binding motif, CinA N-terminal domain; Belongs to the CinA family. (178 aa)
aspAAspartate ammonia-lyase. (464 aa)
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (668 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (304 aa)
AIY18036.1C-terminal domain of CinA type S; Belongs to the CinA family. (160 aa)
AIY18037.2Hypothetical protein. (185 aa)
phoD_2Alkaline phosphatase. (531 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (211 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (156 aa)
AIY18801.1Aspartate racemase. (229 aa)
AIY18852.1Non functional Dihydropteroate synthase 2; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (286 aa)
AIY20171.22-dehydropantoate 2-reductase. (362 aa)
pntANAD(P) transhydrogenase alpha subunit. (511 aa)
pntBNAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (474 aa)
AIY19284.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (344 aa)
AIY19495.2Hypothetical protein. (42 aa)
Your Current Organism:
Pimelobacter simplex
NCBI taxonomy Id: 2045
Other names: ATCC 6946, Arthrobacter simplex, CCUG 23611, CIP 82.106, Corynebacterium simplex, DSM 20130, HAMBI 90, IFO 12069, KCTC 9106, LMG 16261, LMG:16261, NBRC 12069, NCIB 8929, NCIB:8929, Nocardioides simplex, P. simplex
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