STRINGSTRING
AIY15902.2 AIY15902.2 AIY15958.1 AIY15958.1 aceE aceE gabD_1 gabD_1 korB korB AJR18097.1 AJR18097.1 AIY16242.1 AIY16242.1 AIY16296.1 AIY16296.1 fumC fumC AIY16476.1 AIY16476.1 gltA gltA gabD2_1 gabD2_1 sucC sucC sucD sucD mdh mdh AIY16582.1 AIY16582.1 AIY16594.1 AIY16594.1 sdhA sdhA sdhC sdhC AIY16788.2 AIY16788.2 AIY17040.2 AIY17040.2 AIY19850.2 AIY19850.2 AIY17262.1 AIY17262.1 gabT gabT AIY17292.2 AIY17292.2 atoB_2 atoB_2 AIY17700.1 AIY17700.1 AIY17847.1 AIY17847.1 AIY20000.2 AIY20000.2 AIY18080.1 AIY18080.1 AJR18541.1 AJR18541.1 AIY18081.1 AIY18081.1 AIY18082.1 AIY18082.1 AIY20057.2 AIY20057.2 vorA vorA AIY20058.2 AIY20058.2 AIY18426.1 AIY18426.1 AIY18514.1 AIY18514.1 lpdA lpdA gabD_2 gabD_2 korA korA AIY18842.1 AIY18842.1 AIY19115.1 AIY19115.1 AIY19116.1 AIY19116.1 pdhA pdhA AIY19195.2 AIY19195.2 pckG pckG AIY19281.1 AIY19281.1 AIY19282.1 AIY19282.1 AIY19485.1 AIY19485.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIY15902.2Pyruvate carboxylase. (1097 aa)
AIY15958.1Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (412 aa)
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (880 aa)
gabD_1Succinate-semialdehyde dehydrogenase [NAD]. (455 aa)
korB2-oxoglutarate oxidoreductase, beta subunit. (368 aa)
AJR18097.12-oxoglutarate oxidoreductase, alpha subunit. (655 aa)
AIY16242.1Citrate synthase (si); Belongs to the citrate synthase family. (367 aa)
AIY16296.1Aldehyde dehydrogenase. (452 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
AIY16476.1Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (563 aa)
gltACitrate synthase (si); Belongs to the citrate synthase family. (429 aa)
gabD2_1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (554 aa)
sucCSuccinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
sucDSuccinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)
AIY16582.1Isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. (729 aa)
AIY16594.1Succinate dehydrogenase iron-sulfur protein. (247 aa)
sdhASuccinate dehydrogenase flavoprotein subunit. (674 aa)
sdhCSuccinate dehydrogenase cytochrome b subunit. (213 aa)
AIY16788.2NADP-dependent malic enzyme. (452 aa)
AIY17040.2NAD-dependent malic enzyme. (394 aa)
AIY19850.2Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex. (1222 aa)
AIY17262.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (461 aa)
gabTGamma-aminobutyrate:alpha-ketoglutarate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (447 aa)
AIY17292.2Aconitate hydratase. (808 aa)
atoB_2acetyl-CoA acetyltransferase, Mycobacterial subgroup fadA6; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
AIY17700.1PF00070 family, FAD-dependent NAD(P)-disulfide oxidoreductase. (461 aa)
AIY17847.1Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (604 aa)
AIY20000.2Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (940 aa)
AIY18080.1Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (80 aa)
AJR18541.1Acetoin dehydrogenase E1 component alpha-subunit. (323 aa)
AIY18081.1Pyruvate dehydrogenase E1 component beta subunit. (330 aa)
AIY18082.1Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex. (217 aa)
AIY20057.22-oxoglutarate oxidoreductase, gamma subunit. (200 aa)
vorA2-oxoglutarate oxidoreductase, alpha subunit. (368 aa)
AIY20058.22-oxoglutarate oxidoreductase, beta subunit. (271 aa)
AIY18426.12-oxoglutarate oxidoreductase, delta subunit, putative. (81 aa)
AIY18514.1Dihydrolipoamide dehydrogenase. (455 aa)
lpdADihydrolipoamide dehydrogenase. (466 aa)
gabD_2Succinic semialdehyde dehydrogenase gabD2; Belongs to the aldehyde dehydrogenase family. (520 aa)
korA2-oxoglutarate oxidoreductase, alpha subunit. (629 aa)
AIY18842.12-oxoglutarate oxidoreductase, beta subunit. (320 aa)
AIY19115.1Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (455 aa)
AIY19116.1Pyruvate dehydrogenase E1 component beta subunit. (325 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit. (377 aa)
AIY19195.22,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family. (254 aa)
pckGPhosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (606 aa)
AIY19281.1Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (423 aa)
AIY19282.1Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit. (727 aa)
AIY19485.1Aldehyde dehydrogenase. (447 aa)
Your Current Organism:
Pimelobacter simplex
NCBI taxonomy Id: 2045
Other names: ATCC 6946, Arthrobacter simplex, CCUG 23611, CIP 82.106, Corynebacterium simplex, DSM 20130, HAMBI 90, IFO 12069, KCTC 9106, LMG 16261, LMG:16261, NBRC 12069, NCIB 8929, NCIB:8929, Nocardioides simplex, P. simplex
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