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gabD_1 gabD_1 korB korB AJR18097.1 AJR18097.1 AIY16242.1 AIY16242.1 fumC fumC AIY16476.1 AIY16476.1 gltA gltA sucC sucC sucD sucD mdh mdh AIY16582.1 AIY16582.1 AIY16594.1 AIY16594.1 sdhA sdhA sdhC sdhC AIY16788.2 AIY16788.2 AIY17040.2 AIY17040.2 AIY17262.1 AIY17262.1 AIY17292.2 AIY17292.2 atoB_2 atoB_2 AIY20057.2 AIY20057.2 vorA vorA AIY20058.2 AIY20058.2 AIY18426.1 AIY18426.1 gabD_2 gabD_2 korA korA AIY18842.1 AIY18842.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gabD_1Succinate-semialdehyde dehydrogenase [NAD]. (455 aa)
korB2-oxoglutarate oxidoreductase, beta subunit. (368 aa)
AJR18097.12-oxoglutarate oxidoreductase, alpha subunit. (655 aa)
AIY16242.1Citrate synthase (si); Belongs to the citrate synthase family. (367 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
AIY16476.1Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (563 aa)
gltACitrate synthase (si); Belongs to the citrate synthase family. (429 aa)
sucCSuccinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
sucDSuccinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)
AIY16582.1Isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. (729 aa)
AIY16594.1Succinate dehydrogenase iron-sulfur protein. (247 aa)
sdhASuccinate dehydrogenase flavoprotein subunit. (674 aa)
sdhCSuccinate dehydrogenase cytochrome b subunit. (213 aa)
AIY16788.2NADP-dependent malic enzyme. (452 aa)
AIY17040.2NAD-dependent malic enzyme. (394 aa)
AIY17262.1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (461 aa)
AIY17292.2Aconitate hydratase. (808 aa)
atoB_2acetyl-CoA acetyltransferase, Mycobacterial subgroup fadA6; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
AIY20057.22-oxoglutarate oxidoreductase, gamma subunit. (200 aa)
vorA2-oxoglutarate oxidoreductase, alpha subunit. (368 aa)
AIY20058.22-oxoglutarate oxidoreductase, beta subunit. (271 aa)
AIY18426.12-oxoglutarate oxidoreductase, delta subunit, putative. (81 aa)
gabD_2Succinic semialdehyde dehydrogenase gabD2; Belongs to the aldehyde dehydrogenase family. (520 aa)
korA2-oxoglutarate oxidoreductase, alpha subunit. (629 aa)
AIY18842.12-oxoglutarate oxidoreductase, beta subunit. (320 aa)
Your Current Organism:
Pimelobacter simplex
NCBI taxonomy Id: 2045
Other names: ATCC 6946, Arthrobacter simplex, CCUG 23611, CIP 82.106, Corynebacterium simplex, DSM 20130, HAMBI 90, IFO 12069, KCTC 9106, LMG 16261, LMG:16261, NBRC 12069, NCIB 8929, NCIB:8929, Nocardioides simplex, P. simplex
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