STRINGSTRING
AIY15929.2 AIY15929.2 AIY15999.1 AIY15999.1 ispD ispD AIY16495.1 AIY16495.1 zwf_1 zwf_1 eno eno AIY17162.1 AIY17162.1 AIY17163.1 AIY17163.1 pfkA1 pfkA1 AIY17235.2 AIY17235.2 AIY17590.1 AIY17590.1 talA talA pgi pgi AIY17593.2 AIY17593.2 tpiA tpiA pgk pgk gapA gapA rpe rpe gno gno zwf zwf AIY18513.1 AIY18513.1 AIY18631.2 AIY18631.2 gpmA gpmA AIY18810.1 AIY18810.1 fbaA fbaA zwf-2 zwf-2 edd edd AIY19294.1 AIY19294.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIY15929.2NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (459 aa)
AIY15999.13-oxoacyl-[acyl-carrier protein] reductase. (261 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (469 aa)
AIY16495.1Fructose-1,6-bisphosphatase, GlpX type. (337 aa)
zwf_1Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (489 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
AIY17162.1Putative sugar kinase. (309 aa)
AIY17163.1Putative sugar kinase. (302 aa)
pfkA16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
AIY17235.2Pyruvate kinase; Belongs to the pyruvate kinase family. (460 aa)
AIY17590.1Transketolase; Belongs to the transketolase family. (703 aa)
talATransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (368 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
AIY17593.26-phosphogluconolactonase, eukaryotic type. (103 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (266 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (401 aa)
gapANAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (330 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (221 aa)
gno3-oxoacyl-[acyl-carrier protein] reductase. (253 aa)
zwfHypothetical protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (485 aa)
AIY18513.1Ribose 5-phosphate isomerase B. (168 aa)
AIY18631.2Putative N-acetyl-glucosamine kinase 2, ROK family. (298 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
AIY18810.13-oxoacyl-[acyl-carrier protein] reductase. (249 aa)
fbaAFructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (343 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (488 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (617 aa)
AIY19294.14-hydroxy-2-oxoglutarate aldolase, 2-dehydro-3-deoxyphosphogluconate aldolase. (212 aa)
Your Current Organism:
Pimelobacter simplex
NCBI taxonomy Id: 2045
Other names: ATCC 6946, Arthrobacter simplex, CCUG 23611, CIP 82.106, Corynebacterium simplex, DSM 20130, HAMBI 90, IFO 12069, KCTC 9106, LMG 16261, LMG:16261, NBRC 12069, NCIB 8929, NCIB:8929, Nocardioides simplex, P. simplex
Server load: low (18%) [HD]