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AJR17971.1 | Hydroxymethylpyrimidine ABC transporter, substrate-binding component. (366 aa) | ||||
AIY19550.1 | Hypothetical protein. (125 aa) | ||||
ribA-2 | GTP cyclohydrolase II. (225 aa) | ||||
AIY19284.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (344 aa) | ||||
AIY19191.1 | Creatinine amidohydrolase. (227 aa) | ||||
AIY20171.2 | 2-dehydropantoate 2-reductase. (362 aa) | ||||
AIY19043.1 | Oxidoreductase of aldo/keto reductase family, subgroup 1. (283 aa) | ||||
AIY19022.1 | PhnB protein. (142 aa) | ||||
AIY18949.1 | GlcG protein. (140 aa) | ||||
AIY18724.1 | Pyridoxal kinase; Belongs to the pyridoxine kinase family. (287 aa) | ||||
kbl_2 | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (395 aa) | ||||
AIY18436.2 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (134 aa) | ||||
bioD | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (226 aa) | ||||
AIY18292.1 | 8-amino-7-oxononanoate synthase. (375 aa) | ||||
bioA | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (427 aa) | ||||
bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (356 aa) | ||||
thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (323 aa) | ||||
AJR18542.1 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa) | ||||
AIY18068.2 | CobN component of cobalt chelatase involved in B12 biosynthesis. (1221 aa) | ||||
AIY18067.1 | Precorrin-6A synthase. (240 aa) | ||||
cobQ | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (464 aa) | ||||
cobK | Cobalt-precorrin-6x reductase. (243 aa) | ||||
cobD | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (306 aa) | ||||
cobO | Cobinamide adenolsyltransferase. (193 aa) | ||||
cobM | Cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. (252 aa) | ||||
AIY19993.2 | Cobalt-precorrin-6y C5-methyltransferase. (392 aa) | ||||
cobI | Cobalt-precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. (512 aa) | ||||
AIY18053.2 | Cobalt-precorrin-8x methylmutase. (232 aa) | ||||
cobU_2 | Adenosylcobinamide-phosphate guanylyltransferase. (176 aa) | ||||
cobS | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (255 aa) | ||||
cobU_1 | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (348 aa) | ||||
panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (304 aa) | ||||
AIY17908.2 | Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa) | ||||
pdxS | Pyridoxine biosynthesis glutamine amidotransferase, synthase subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (272 aa) | ||||
pdxT | Pyridoxine biosynthesis glutamine amidotransferase, glutaminase subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (198 aa) | ||||
AJR18431.1 | Hypothetical protein. (482 aa) | ||||
AIY17523.2 | Putative lyase. (137 aa) | ||||
phnB | PhnB protein. (152 aa) | ||||
AIY17391.1 | Hypothetical protein. (134 aa) | ||||
AIY17355.1 | Hypothetical protein. (151 aa) | ||||
ribH_1 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (161 aa) | ||||
ribA | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. (311 aa) | ||||
AIY17350.1 | Riboflavin synthase eubacterial/eukaryotic. (202 aa) | ||||
AIY19896.2 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (353 aa) | ||||
dxs2 | 1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (636 aa) | ||||
AIY17275.1 | FAD-dependent oxidoreductase. (439 aa) | ||||
AIY17109.2 | Riboflavin kinase; Belongs to the ribF family. (313 aa) | ||||
AIY17075.1 | ATP:Cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (201 aa) | ||||
AIY16766.1 | Additional substrate-specific component NikN of nickel ECF transporter. (114 aa) | ||||
AJR18241.1 | Substrate-specific component NikM of nickel ECF transporter. (229 aa) | ||||
AIY16534.1 | Hypothetical protein. (391 aa) | ||||
thiC | Hydroxymethylpyrimidine phosphate synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (554 aa) | ||||
AIY16483.2 | Hydroxymethylpyrimidine phosphate kinase ThiD. (345 aa) | ||||
thiG | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (254 aa) | ||||
AIY16480.1 | Sulfur carrier protein ThiS, Opine oxidase subunit C. (69 aa) | ||||
AIY16479.1 | Glycine oxidase ThiO. (332 aa) | ||||
thiE_2 | Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (196 aa) | ||||
AIY16376.1 | Dihydrofolate reductase. (189 aa) | ||||
serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (372 aa) | ||||
AIY16225.1 | Methyltransferase. (403 aa) | ||||
panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (139 aa) | ||||
panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (292 aa) | ||||
AIY16040.1 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (189 aa) | ||||
folB | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (135 aa) | ||||
folP | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (291 aa) | ||||
cobW | Putative metal chaperone, involved in Zn homeostasis. (341 aa) | ||||
AIY15936.1 | Putative metal chaperone, involved in Zn homeostasis. (354 aa) | ||||
kbl_1 | 2-amino-3-ketobutyrate coenzyme A ligase. (376 aa) | ||||
AIY15780.1 | Oxidoreductase of aldo/keto reductase family, subgroup 1. (269 aa) | ||||
AIY15589.1 | Putative quinone binding protein. (134 aa) |