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AIY15616.1 AIY15616.1 AIY15620.1 AIY15620.1 AIY15633.1 AIY15633.1 AIY15659.1 AIY15659.1 fadB fadB AIY15692.1 AIY15692.1 acs_2 acs_2 paaG_1 paaG_1 AIY16020.1 AIY16020.1 sucC sucC sucD sucD paaG_3 paaG_3 AIY19775.2 AIY19775.2 AIY16614.1 AIY16614.1 AIY16637.1 AIY16637.1 AIY16797.1 AIY16797.1 AIY19858.2 AIY19858.2 AIY17091.1 AIY17091.1 gabT gabT atoB_1 atoB_1 AIY17619.1 AIY17619.1 atoB_3 atoB_3 AIY17642.2 AIY17642.2 AIY17646.1 AIY17646.1 atoB_2 atoB_2 AIY17913.1 AIY17913.1 AIY18143.1 AIY18143.1 AJR18584.1 AJR18584.1 AIY18301.2 AIY18301.2 AIY18471.2 AIY18471.2 AIY18491.2 AIY18491.2 lpdA lpdA AIY18815.1 AIY18815.1 AIY18833.2 AIY18833.2 AIY19122.1 AIY19122.1 paaG_5 paaG_5 atoB_4 atoB_4 AIY19282.1 AIY19282.1 AIY20186.2 AIY20186.2 AIY19335.1 AIY19335.1 AIY19381.1 AIY19381.1 AIY20228.2 AIY20228.2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AIY15616.13-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
AIY15620.13-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
AIY15633.13-ketoacyl-CoA thiolase, acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
AIY15659.13-ketoacyl-CoA thiolase, acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
fadBShort chain enoyl-CoA hydratase [isoleucine degradation]/3-hydroxyacyl-CoA dehydrogenase. (728 aa)
AIY15692.1Methylcrotonyl-CoA carboxylase biotin-containing subunit. (657 aa)
acs_2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (659 aa)
paaG_1Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (272 aa)
AIY16020.1Acyl-coenzyme A oxidase 1, peroxisomal. (657 aa)
sucCSuccinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
sucDSuccinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (298 aa)
paaG_3Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa)
AIY19775.2Methylmalonyl-CoA mutase. (548 aa)
AIY16614.1Methylmalonyl-CoA mutase. (721 aa)
AIY16637.1Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (256 aa)
AIY16797.13-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
AIY19858.2Methylmalonyl-CoA epimerase. (152 aa)
AIY17091.13-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
gabTGamma-aminobutyrate:alpha-ketoglutarate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (447 aa)
atoB_13-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa)
AIY17619.1enoyl-CoA hydratase echA19. (270 aa)
atoB_3acetyl-CoA acetyltransferase ltp3. (386 aa)
AIY17642.2acetyl-CoA-acetyltransferase, Mycobacterial subgroup fadA5; Belongs to the thiolase-like superfamily. Thiolase family. (383 aa)
AIY17646.1enoyl-CoA hydratase echA20. (253 aa)
atoB_2acetyl-CoA acetyltransferase, Mycobacterial subgroup fadA6; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
AIY17913.1Methylmalonate-semialdehyde dehydrogenase. (496 aa)
AIY18143.1Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative. (693 aa)
AJR18584.1Sulfate-transport ATP-binding protein ABC transporter CysA1. (697 aa)
AIY18301.2Propionyl-CoA carboxylase beta chain. (433 aa)
AIY18471.2Acetyl-coenzyme A carboxyl transferase alpha chain. (545 aa)
AIY18491.2Biotin carboxylase of acetyl-CoA carboxylase. (513 aa)
lpdADihydrolipoamide dehydrogenase. (466 aa)
AIY18815.1enoyl-CoA hydratase echA1; Belongs to the enoyl-CoA hydratase/isomerase family. (269 aa)
AIY18833.2Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative. (704 aa)
AIY19122.1Acetyl-coenzyme A synthetase. (567 aa)
paaG_5enoyl-CoA hydratase. (291 aa)
atoB_4acetyl-CoA acetyltransferase, Mycobacterial subgroup fadA3; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)
AIY19282.1Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit. (727 aa)
AIY20186.2Enoyl-CoA hydratase. (208 aa)
AIY19335.1Biotin carboxyl carrier protein. (77 aa)
AIY19381.1Methylcrotonyl-CoA carboxylase biotin-containing subunit. (599 aa)
AIY20228.23-hydroxyisobutyryl-CoA hydrolase. (338 aa)
Your Current Organism:
Pimelobacter simplex
NCBI taxonomy Id: 2045
Other names: ATCC 6946, Arthrobacter simplex, CCUG 23611, CIP 82.106, Corynebacterium simplex, DSM 20130, HAMBI 90, IFO 12069, KCTC 9106, LMG 16261, LMG:16261, NBRC 12069, NCIB 8929, NCIB:8929, Nocardioides simplex, P. simplex
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