STRINGSTRING
thiD thiD ACN99025.1 ACN99025.1 modB modB ACN98525.1 ACN98525.1 ACN98880.1 ACN98880.1 modA modA ACN99110.1 ACN99110.1 ACN98150.1 ACN98150.1 ACN98523.1 ACN98523.1 pdxJ pdxJ ACN98198.1 ACN98198.1 rlmN rlmN ACN98158.1 ACN98158.1 pgpA pgpA ACN98865.1 ACN98865.1 ACN99658.1 ACN99658.1 ACN98636.1 ACN98636.1 ACN99273.1 ACN99273.1 ACN98867.1 ACN98867.1 ACN98325.1 ACN98325.1 thiO thiO moaE moaE ACN99126.1 ACN99126.1 moaA moaA ACN98869.1 ACN98869.1 ACN99589.1 ACN99589.1 pgsA_1 pgsA_1 mqnA mqnA ACN98734.1 ACN98734.1 thiE thiE mqnE mqnE ACN99155.1 ACN99155.1 ACN98961.1 ACN98961.1 ACN98262.1 ACN98262.1 ACN99393.1 ACN99393.1 ACN98649.1 ACN98649.1 ACN98816.1 ACN98816.1 ACN98980.1 ACN98980.1 ACN99769.1 ACN99769.1 ACN99192.1 ACN99192.1 ACN98258.1 ACN98258.1 ACN98874.1 ACN98874.1 ACN99649.1 ACN99649.1 ACN99615.1 ACN99615.1 ACN99097.1 ACN99097.1 ACN99647.1 ACN99647.1 def_2 def_2 lgt lgt ACN98217.1 ACN98217.1 mobA mobA ACN98568.1 ACN98568.1 ACN98902.1 ACN98902.1 mobB mobB ACN98979.1 ACN98979.1 ACN98466.1 ACN98466.1 ACN99274.1 ACN99274.1 ACN98515.1 ACN98515.1 ACN98619.1 ACN98619.1 ACN99596.1 ACN99596.1 pdxA pdxA pgsA_2 pgsA_2 thiS thiS thiC thiC ACN99444.1 ACN99444.1 sppA sppA ACN99016.1 ACN99016.1 ACN98482.1 ACN98482.1 ACN99205.1 ACN99205.1 ACN98678.1 ACN98678.1 ACN99655.1 ACN99655.1 ACN99045.1 ACN99045.1 ACN99820.1 ACN99820.1 ubiX ubiX ACN98811.1 ACN98811.1 coaD coaD ACN98783.1 ACN98783.1 ACN98937.1 ACN98937.1 ACN99491.1 ACN99491.1 ACN98509.1 ACN98509.1 ACN98107.1 ACN98107.1 ACN99747.1 ACN99747.1 ACN98168.1 ACN98168.1 mqnD mqnD thiG thiG mqnC mqnC ACN98945.1 ACN98945.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
thiDPhosphomethylpyrimidine kinase; Identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097. (274 aa)
ACN99025.1Spermidine/putrescine import ATP-binding protein PotA; Identified by match to protein family HMM PF00005. (285 aa)
modBMolybdate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (228 aa)
ACN98525.1Conserved hypothetical protein. (127 aa)
ACN98880.1Conserved hypothetical protein. (47 aa)
modAMolybdate ABC transporter, periplasmic molybdate-binding protein; Identified by match to protein family HMM PF01547; match to protein family HMM TIGR01256. (257 aa)
ACN99110.1Putative Sel1 domain protein repeat-containing protein. (72 aa)
ACN98150.1MjaVIP. (178 aa)
ACN98523.1Modification methylase MjaVI (N-4 cytosine-specificmethyltransferase MjaVI) (M.MjaVI); Identified by match to protein family HMM PF01555; Belongs to the N(4)/N(6)-methyltransferase family. (325 aa)
pdxJPyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (244 aa)
ACN98198.1Menaquinone biosynthesis decarboxylase, family; Identified by match to protein family HMM PF01977; match to protein family HMM TIGR00148; match to protein family HMM TIGR03701; Belongs to the UbiD family. (491 aa)
rlmNRadical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (353 aa)
ACN98158.1Mov34/MPN/PAD-1; Identified by match to protein family HMM PF01398. (140 aa)
pgpAIdentified by match to protein family HMM PF04608. (160 aa)
ACN98865.1Thiamine-phosphate pyrophosphorylase; Identified by match to protein family HMM PF02581. (181 aa)
ACN99658.1Conserved hypothetical protein. (342 aa)
ACN98636.1Conserved hypothetical protein; Identified by match to protein family HMM PF05728. (188 aa)
ACN99273.1Molybdenum cofactor biosynthesis protein A; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (412 aa)
ACN98867.1Peptidase, M48 family; Identified by match to protein family HMM PF00515; match to protein family HMM PF01435. (426 aa)
ACN98325.1Conserved domain protein; Identified by match to protein family HMM PF01106. (79 aa)
thiOGlycine oxidase ThiO; Identified by match to protein family HMM PF01266; match to protein family HMM TIGR02352. (365 aa)
moaEMolybdopterin converting factor, subunit 2; Identified by match to protein family HMM PF02391. (138 aa)
ACN99126.1Molybdenum cofactor biosynthesis protein; Identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177. (176 aa)
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (321 aa)
ACN98869.1Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01687. (93 aa)
ACN99589.1Cyclic pyranopterin monophosphate synthase; Identified by match to protein family HMM PF00994; match to protein family HMM PF01967; match to protein family HMM TIGR00177; match to protein family HMM TIGR00581. (304 aa)
pgsA_1CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (186 aa)
mqnAConserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). (525 aa)
ACN98734.1Putative 4-hydroxybenzoate polyprenyltransferase; Identified by match to protein family HMM PF01040; match to protein family HMM TIGR01475; Belongs to the UbiA prenyltransferase family. (290 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (204 aa)
mqnEPutative menaquinone biosynthesis protein, family; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (372 aa)
ACN99155.1Uba/thif-type NAD/fad binding fold protein; Identified by match to protein family HMM PF00581. (116 aa)
ACN98961.1Conserved hypothetical protein; Identified by match to protein family HMM PF04323. (149 aa)
ACN98262.1Identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738. (142 aa)
ACN99393.1Cupin domain protein; Identified by match to protein family HMM PF07883. (107 aa)
ACN98649.1Putative membrane protein. (377 aa)
ACN98816.1Hypothetical protein; Identified by Glimmer3; putative. (48 aa)
ACN98980.1Hypothetical protein; Identified by Glimmer3; putative. (149 aa)
ACN99769.1Hypothetical protein; Identified by Glimmer3; putative. (222 aa)
ACN99192.1Hypothetical protein; Identified by Glimmer3; putative. (271 aa)
ACN98258.1Hypothetical protein; Identified by Glimmer3; putative. (486 aa)
ACN98874.1Hypothetical protein; Identified by Glimmer3; putative. (308 aa)
ACN99649.1Conserved hypothetical protein; Identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033. (251 aa)
ACN99615.1Hypothetical protein; Identified by Glimmer3; putative. (98 aa)
ACN99097.1Conserved domain protein; Identified by match to protein family HMM PF02597. (70 aa)
ACN99647.1PP-loop domain protein; Identified by match to protein family HMM PF01171; match to protein family HMM TIGR00269; Belongs to the TtcA family. (303 aa)
def_2Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (179 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (259 aa)
ACN98217.1Bifunctional protein FolC; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family. (411 aa)
mobAFormate dehydrogenase accessory protein FdhD; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (201 aa)
ACN98568.1linocin_M18 bacteriocin protein; Identified by match to protein family HMM PF04454. (278 aa)
ACN98902.1Hypothetical protein; Identified by Glimmer3; putative. (62 aa)
mobBMolybdopterin-guanine dinucleotide biosynthesis protein B; Identified by match to protein family HMM PF03205; match to protein family HMM TIGR00176. (165 aa)
ACN98979.1Conserved hypothetical protein. (260 aa)
ACN98466.1Molybdopterin-synthase adenylyltransferase; Identified by match to protein family HMM PF00899; match to protein family HMM PF05237. (271 aa)
ACN99274.1Conserved domain protein; Identified by match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. (77 aa)
ACN98515.1DsrE protein; Identified by match to protein family HMM PF02635. (100 aa)
ACN98619.1DsrE protein; Identified by match to protein family HMM PF02635. (117 aa)
ACN99596.1Protein TusB (tRNA 2-thiouridine synthesizing protein B). (80 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. (329 aa)
pgsA_2CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (171 aa)
thiSThiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683. (67 aa)
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (452 aa)
ACN99444.1Conserved hypothetical protein; Identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; Belongs to the HesB/IscA family. (115 aa)
sppASignal peptide peptidase SppA, 36K type; Identified by match to protein family HMM PF01343; match to protein family HMM TIGR00706. (276 aa)
ACN99016.1tRNA methyltransferase complex GCD14 subunit; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. (252 aa)
ACN98482.1Conserved hypothetical protein. (218 aa)
ACN99205.1Cation transporting ATPase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01494. (98 aa)
ACN98678.1Cation-transporting ATPase PacL; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01494. (223 aa)
ACN99655.1Cation-transporting ATPase Pma1; Identified by match to protein family HMM PF00122; match to protein family HMM PF00690; match to protein family HMM TIGR01494. (371 aa)
ACN99045.1Hypothetical protein; Identified by Glimmer3; putative. (79 aa)
ACN99820.1Recombinase; Identified by match to protein family HMM PF00589; match to protein family HMM PF02899; Belongs to the 'phage' integrase family. (297 aa)
ubiXPhenylacrylic acid decarboxylase (PAD); Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (189 aa)
ACN98811.1Conserved hypothetical protein; Identified by match to protein family HMM PF03602. (170 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (166 aa)
ACN98783.1Putative lipoprotein. (160 aa)
ACN98937.1Conserved domain protein; Identified by match to protein family HMM PF01106. (84 aa)
ACN99491.1Conserved hypothetical protein. (73 aa)
ACN98509.1Sulfurtransferase TusA; Identified by match to protein family HMM PF01206; Belongs to the sulfur carrier protein TusA family. (77 aa)
ACN98107.1Fe-S cluster assembly protein NifU; Identified by match to protein family HMM PF01592. (154 aa)
ACN99747.1Cysteine desulfurase; Identified by match to protein family HMM PF00266. (402 aa)
ACN98168.1Hypothetical protein; Identified by Glimmer3; putative. (72 aa)
mqnDConserved hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (275 aa)
thiGThiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (266 aa)
mqnCMenaquinone biosynthesis protein, family; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (359 aa)
ACN98945.1Cysteine desulfurase (Nitrogenase metalloclustersbiosynthesis protein NifS); Identified by match to protein family HMM PF00266. (376 aa)
Your Current Organism:
Sulfurihydrogenibium azorense
NCBI taxonomy Id: 204536
Other names: Aquificaceae bacterium Az-Fu1, S. azorense Az-Fu1, Sulfurihydrogenibium azorense Az-Fu1, Sulfurihydrogenibium azorense str. Az-Fu1, Sulfurihydrogenibium azorense strain Az-Fu1
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