node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACN98993.1 | coaX | SULAZ_1713 | SULAZ_1714 | N-acetylmuramoyl-L-alanine amidase AmiC; Identified by match to protein family HMM PF01520. | Type III pantothenate kinase (Pantothenic acid kinase)(PanK-III); Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.800 |
coaBC | coaX | SULAZ_0961 | SULAZ_1714 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Type III pantothenate kinase (Pantothenic acid kinase)(PanK-III); Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.939 |
coaBC | panC | SULAZ_0961 | SULAZ_0018 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.867 |
coaX | ACN98993.1 | SULAZ_1714 | SULAZ_1713 | Type III pantothenate kinase (Pantothenic acid kinase)(PanK-III); Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | N-acetylmuramoyl-L-alanine amidase AmiC; Identified by match to protein family HMM PF01520. | 0.800 |
coaX | coaBC | SULAZ_1714 | SULAZ_0961 | Type III pantothenate kinase (Pantothenic acid kinase)(PanK-III); Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.939 |
coaX | panC | SULAZ_1714 | SULAZ_0018 | Type III pantothenate kinase (Pantothenic acid kinase)(PanK-III); Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.960 |
coaX | panD | SULAZ_1714 | SULAZ_1371 | Type III pantothenate kinase (Pantothenic acid kinase)(PanK-III); Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.686 |
panB | panC | SULAZ_1392 | SULAZ_0018 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.998 |
panB | panD | SULAZ_1392 | SULAZ_1371 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.956 |
panB | panE | SULAZ_1392 | SULAZ_1670 | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.983 |
panC | coaBC | SULAZ_0018 | SULAZ_0961 | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.867 |
panC | coaX | SULAZ_0018 | SULAZ_1714 | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | Type III pantothenate kinase (Pantothenic acid kinase)(PanK-III); Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.960 |
panC | panB | SULAZ_0018 | SULAZ_1392 | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.998 |
panC | panD | SULAZ_0018 | SULAZ_1371 | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.996 |
panC | panE | SULAZ_0018 | SULAZ_1670 | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.934 |
panD | coaX | SULAZ_1371 | SULAZ_1714 | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | Type III pantothenate kinase (Pantothenic acid kinase)(PanK-III); Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.686 |
panD | panB | SULAZ_1371 | SULAZ_1392 | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.956 |
panD | panC | SULAZ_1371 | SULAZ_0018 | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.996 |
panE | panB | SULAZ_1670 | SULAZ_1392 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.983 |
panE | panC | SULAZ_1670 | SULAZ_0018 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.934 |