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| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (258 aa) |
| | ABF39068.1 | Phosphoribosyltransferase. (184 aa) |
| | ABF39088.1 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (164 aa) |
| | ABF39124.1 | FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. (447 aa) |
| | ABF39138.1 | Nicotinate-nucleotide pyrophosphorylase (carboxylating); Belongs to the NadC/ModD family. (292 aa) |
| | birA | Biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (363 aa) |
| | coaX | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (274 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (425 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (239 aa) |
| | ABF39286.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (351 aa) |
| | pyrD | Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (321 aa) |
| | ABF39405.1 | Delta-1-pyrroline-5-carboxylate dehydrogenase. (531 aa) |
| | ABF39555.1 | Peptidase T2, asparaginase 2. (308 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (167 aa) |
| | ABF39573.1 | L-aspartate aminotransferase apoenzyme. (399 aa) |
| | ABF39581.1 | Aspartate-ammonia ligase. (379 aa) |
| | argD | Acetylornithine aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (426 aa) |
| | ABF39693.1 | L-threonine ammonia-lyase. (413 aa) |
| | ABF39734.1 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (334 aa) |
| | ABF39900.1 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (450 aa) |
| | ABF39937.1 | Pyridoxal-dependent decarboxylase. (466 aa) |
| | purS | Phosphoribosylformylglycinamidine synthetase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to ass [...] (80 aa) |
| | ABF40043.1 | Peptidase dimerization. (337 aa) |
| | nadK | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (285 aa) |
| | ABF40079.1 | Phenylalanine 4-hydroxylase. (250 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (260 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (221 aa) |
| | trpB | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (408 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (261 aa) |
| | ABF40164.1 | Chorismate mutase. (86 aa) |
| | ABF40165.1 | Prephenate dehydrogenase. (286 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (195 aa) |
| | dcd | dCTP deaminase; Catalyzes the deamination of dCTP to dUTP. (184 aa) |
| | ribH | Riboflavin synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (309 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (499 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (426 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (258 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (409 aa) |
| | ABF40284.1 | Pyridoxal-dependent decarboxylase. (477 aa) |
| | ABF40340.1 | L-proline dehydrogenase. (306 aa) |
| | katG | Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (752 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (280 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (315 aa) |
| | ABF40482.1 | L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (408 aa) |
| | ABF40483.1 | Homoserine dehydrogenase. (431 aa) |
| | ABF40484.1 | Aspartate kinase; Belongs to the aspartokinase family. (469 aa) |
| | ABF40743.1 | Purine and other phosphorylase, family 1. (235 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (515 aa) |
| | ABF40818.1 | Hypothetical protein. (235 aa) |
| | ABF40819.1 | Conserved hypothetical protein. (445 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (323 aa) |
| | ABF40821.1 | Carbamate kinase; Belongs to the carbamate kinase family. (330 aa) |
| | ABF40822.1 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (319 aa) |
| | rocD | Aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (402 aa) |
| | ABF40848.1 | Methionine synthase (B12-dependent). (407 aa) |
| | ABF40849.1 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (909 aa) |
| | ABF40884.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase. (355 aa) |
| | ABF40914.1 | Cystathionine gamma-synthase. (390 aa) |
| | ABF40981.1 | Cystathionine beta-lyase. (407 aa) |
| | ABF40982.1 | Cystathionine gamma-synthase. (400 aa) |
| | ABF40983.1 | Cystathionine beta-lyase. (389 aa) |
| | pheA | Prephenate dehydratase. (283 aa) |
| | ABF41085.1 | Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (332 aa) |
| | ABF41088.1 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (278 aa) |
| | ABF41097.1 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (323 aa) |
| | ABF41098.1 | Serine O-acetyltransferase. (258 aa) |
| | ABF41119.1 | Agmatinase; Belongs to the arginase family. (263 aa) |
| | ABF41148.1 | Conserved hypothetical protein. (286 aa) |
| | ribA | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (224 aa) |
| | ABF41161.1 | Aromatic-L-amino-acid decarboxylase. (479 aa) |
| | ABF41186.1 | MazG family protein. (405 aa) |
| | carA | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (373 aa) |
| | carB | Carbamoyl-phosphate synthase large subunit. (1102 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (231 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (366 aa) |
| | ABF41251.1 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (522 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (318 aa) |
| | ABF41279.1 | Alpha/beta hydrolase; Belongs to the AB hydrolase superfamily. MetX family. (355 aa) |
| | ABF41332.1 | Pterin-4-alpha-carbinolamine dehydratase. (94 aa) |
| | ABF41359.1 | Aspartate semialdehyde dehydrogenase. (350 aa) |
| | ABF41487.1 | Sigma-24, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (202 aa) |
| | ABF41488.1 | Hypothetical protein. (82 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (168 aa) |
| | ABF41490.1 | Hypothetical protein. (253 aa) |
| | ABF41491.1 | Aspartate semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (351 aa) |
| | ABF41492.1 | Aspartate kinase; Belongs to the aspartokinase family. (456 aa) |
| | ABF41493.1 | Dihydrodipicolinate reductase; Belongs to the DapB family. (226 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (300 aa) |
| | ABF41495.1 | O-antigen polymerase. (563 aa) |
| | ABF41496.1 | Hypothetical protein. (280 aa) |
| | ABF41500.1 | Cystathionine gamma-lyase. (385 aa) |
| | ABF41501.1 | Cystathionine beta-synthase (acetylserine-dependent); Belongs to the cysteine synthase/cystathionine beta- synthase family. (315 aa) |
| | nadE | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (556 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (234 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (260 aa) |
| | ABF41650.1 | Haloacid dehalogenase-like hydrolase. (238 aa) |
| | ABF41651.1 | Hypothetical protein. (97 aa) |
| | ABF41690.1 | Fumarase. (476 aa) |
| | ABF41738.1 | Ham1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (210 aa) |
| | ABF41796.1 | Sulfide dehydrogenase (flavoprotein) subunit SudB. (281 aa) |
| | ABF41797.1 | Sulfide dehydrogenase (flavoprotein) subunit SudA. (477 aa) |
| | ABF41804.1 | Phosphoserine phosphatase SerB. (398 aa) |
| | ABF41884.1 | Riboflavin synthase, alpha subunit. (215 aa) |
| | ABF41953.1 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (350 aa) |
| | purN | Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (227 aa) |
| | ABF42032.1 | Aminotransferase. (387 aa) |
| | ABF42055.1 | Uridine kinase; Belongs to the uridine kinase family. (201 aa) |
| | ABF42099.1 | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa) |
| | ABF42111.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase. (340 aa) |
| | ribB | GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (387 aa) |
| | ABF42224.1 | Pyridine nucleotide-disulfide oxidoreductase. (463 aa) |
| | ABF42338.1 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (399 aa) |
| | ABF42427.1 | Homocysteine S-methyltransferase. (617 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (427 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (182 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (435 aa) |
| | ahcY | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (426 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (558 aa) |
| | ABF42682.1 | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. (111 aa) |
| | hisG | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (289 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (415 aa) |
| | hisC | Histidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (356 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (195 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (198 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa) |
| | ABF42689.1 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (228 aa) |
| | ABF42776.1 | Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (412 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (233 aa) |
| | ABF42820.1 | Protein of unknown function DUF201. (343 aa) |
| | hisC-2 | Aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (374 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (442 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (347 aa) |
| | ABF42931.1 | Tryptophanase. (458 aa) |
| | cysS | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (495 aa) |
| | ABF43034.1 | L-threonine synthase. (396 aa) |
| | aroE | 3-dehydroquinate dehydratase / shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA); Belongs to the type-I 3-dehydroquinase family. (613 aa) |
| | trpE | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] (489 aa) |
| | ABF43125.1 | Anthranilate synthase, component II. (191 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (429 aa) |
| | ABF43156.1 | N-acetylglutamate synthase; Belongs to the acetyltransferase family. (174 aa) |
| | argH | Argininosuccinate lyase. (464 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (405 aa) |
| | argF-2 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (338 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (261 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (350 aa) |
| | argR | Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes. (148 aa) |
| | ABF43165.1 | Homoserine dehydrogenase. (340 aa) |
| | ABF43185.1 | NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (464 aa) |
| | ABF43186.1 | Nicotinamide nucleotide transhydrogenase, subunit alpha. (103 aa) |
| | ABF43187.1 | NAD(P)(+) transhydrogenase (AB-specific). (387 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (393 aa) |
| | nadA | Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (370 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (307 aa) |
| | purH | IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase. (523 aa) |
| | ABF43496.1 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (302 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (379 aa) |
| | ABF43499.1 | O-acetylhomoserine sulfhydrolase. (447 aa) |
| | purE | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa) |
| | pyrR | Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (174 aa) |
| | pyrB | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (303 aa) |
| | ABF43593.1 | Aspartate racemase; Belongs to the aspartate/glutamate racemases family. (230 aa) |
| | ABF43596.1 | Arginase; Belongs to the arginase family. (315 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (482 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (768 aa) |
| | panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (291 aa) |
| | panB | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (295 aa) |
