STRINGSTRING
ABF39286.1 ABF39286.1 ABF39573.1 ABF39573.1 ABF39693.1 ABF39693.1 ABF39900.1 ABF39900.1 ABF39937.1 ABF39937.1 ABF40079.1 ABF40079.1 trpC trpC trpF trpF trpB trpB trpA trpA ABF40164.1 ABF40164.1 ABF40165.1 ABF40165.1 ABF40284.1 ABF40284.1 katG katG thrB thrB ABF40482.1 ABF40482.1 ABF40483.1 ABF40483.1 ABF40484.1 ABF40484.1 ABF40743.1 ABF40743.1 ABF40848.1 ABF40848.1 ABF40849.1 ABF40849.1 ABF40884.1 ABF40884.1 ABF40914.1 ABF40914.1 ABF40981.1 ABF40981.1 ABF40982.1 ABF40982.1 ABF40983.1 ABF40983.1 pheA pheA ABF41085.1 ABF41085.1 ABF41097.1 ABF41097.1 ABF41098.1 ABF41098.1 ABF41161.1 ABF41161.1 aroB aroB ABF41279.1 ABF41279.1 ABF41332.1 ABF41332.1 ABF41359.1 ABF41359.1 ABF41487.1 ABF41487.1 ABF41488.1 ABF41488.1 aroK aroK ABF41490.1 ABF41490.1 ABF41491.1 ABF41491.1 ABF41492.1 ABF41492.1 ABF41493.1 ABF41493.1 dapA dapA ABF41495.1 ABF41495.1 ABF41496.1 ABF41496.1 ABF41500.1 ABF41500.1 ABF41501.1 ABF41501.1 dapF dapF ABF41650.1 ABF41650.1 ABF41651.1 ABF41651.1 ABF41804.1 ABF41804.1 ABF42032.1 ABF42032.1 ABF42111.1 ABF42111.1 ABF42427.1 ABF42427.1 lysA lysA aroA aroA ahcY ahcY ABF42682.1 ABF42682.1 hisG hisG hisD hisD hisC hisC hisB hisB hisH hisH hisF hisF ABF42689.1 ABF42689.1 hisC-2 hisC-2 trpD trpD ABF42931.1 ABF42931.1 cysS cysS ABF43034.1 ABF43034.1 aroE aroE trpE trpE ABF43125.1 ABF43125.1 ABF43165.1 ABF43165.1 aroC aroC metXA metXA ABF43499.1 ABF43499.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABF39286.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (351 aa)
ABF39573.1L-aspartate aminotransferase apoenzyme. (399 aa)
ABF39693.1L-threonine ammonia-lyase. (413 aa)
ABF39900.1L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (450 aa)
ABF39937.1Pyridoxal-dependent decarboxylase. (466 aa)
ABF40079.1Phenylalanine 4-hydroxylase. (250 aa)
trpCIndole-3-glycerol phosphate synthase; Belongs to the TrpC family. (260 aa)
trpFPhosphoribosylanthranilate isomerase; Belongs to the TrpF family. (221 aa)
trpBTryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (408 aa)
trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (261 aa)
ABF40164.1Chorismate mutase. (86 aa)
ABF40165.1Prephenate dehydrogenase. (286 aa)
ABF40284.1Pyridoxal-dependent decarboxylase. (477 aa)
katGCatalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (752 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (315 aa)
ABF40482.1L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (408 aa)
ABF40483.1Homoserine dehydrogenase. (431 aa)
ABF40484.1Aspartate kinase; Belongs to the aspartokinase family. (469 aa)
ABF40743.1Purine and other phosphorylase, family 1. (235 aa)
ABF40848.1Methionine synthase (B12-dependent). (407 aa)
ABF40849.1Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (909 aa)
ABF40884.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase. (355 aa)
ABF40914.1Cystathionine gamma-synthase. (390 aa)
ABF40981.1Cystathionine beta-lyase. (407 aa)
ABF40982.1Cystathionine gamma-synthase. (400 aa)
ABF40983.1Cystathionine beta-lyase. (389 aa)
pheAPrephenate dehydratase. (283 aa)
ABF41085.1Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (332 aa)
ABF41097.1Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (323 aa)
ABF41098.1Serine O-acetyltransferase. (258 aa)
ABF41161.1Aromatic-L-amino-acid decarboxylase. (479 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (366 aa)
ABF41279.1Alpha/beta hydrolase; Belongs to the AB hydrolase superfamily. MetX family. (355 aa)
ABF41332.1Pterin-4-alpha-carbinolamine dehydratase. (94 aa)
ABF41359.1Aspartate semialdehyde dehydrogenase. (350 aa)
ABF41487.1Sigma-24, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily. (202 aa)
ABF41488.1Hypothetical protein. (82 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (168 aa)
ABF41490.1Hypothetical protein. (253 aa)
ABF41491.1Aspartate semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (351 aa)
ABF41492.1Aspartate kinase; Belongs to the aspartokinase family. (456 aa)
ABF41493.1Dihydrodipicolinate reductase; Belongs to the DapB family. (226 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (300 aa)
ABF41495.1O-antigen polymerase. (563 aa)
ABF41496.1Hypothetical protein. (280 aa)
ABF41500.1Cystathionine gamma-lyase. (385 aa)
ABF41501.1Cystathionine beta-synthase (acetylserine-dependent); Belongs to the cysteine synthase/cystathionine beta- synthase family. (315 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (260 aa)
ABF41650.1Haloacid dehalogenase-like hydrolase. (238 aa)
ABF41651.1Hypothetical protein. (97 aa)
ABF41804.1Phosphoserine phosphatase SerB. (398 aa)
ABF42032.1Aminotransferase. (387 aa)
ABF42111.13-deoxy-D-arabinoheptulosonate-7-phosphate synthase. (340 aa)
ABF42427.1Homocysteine S-methyltransferase. (617 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (427 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (435 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (426 aa)
ABF42682.1phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. (111 aa)
hisGATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (289 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (415 aa)
hisCHistidinol phosphate aminotransferase apoenzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (356 aa)
hisBImidazoleglycerol-phosphate dehydratase. (195 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (198 aa)
hisFImidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa)
ABF42689.11-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (228 aa)
hisC-2Aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (374 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (347 aa)
ABF42931.1Tryptophanase. (458 aa)
cysScysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (495 aa)
ABF43034.1L-threonine synthase. (396 aa)
aroE3-dehydroquinate dehydratase / shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA); Belongs to the type-I 3-dehydroquinase family. (613 aa)
trpEAnthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] (489 aa)
ABF43125.1Anthranilate synthase, component II. (191 aa)
ABF43165.1Homoserine dehydrogenase. (340 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (393 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (379 aa)
ABF43499.1O-acetylhomoserine sulfhydrolase. (447 aa)
Your Current Organism:
Koribacter versatilis
NCBI taxonomy Id: 204669
Other names: Acidobacteria bacterium Ellin345, C. Koribacter versatilis Ellin345, Candidatus Koribacter versatilis Ellin345, Koribacter versatilis Ellin345, bacterium Ellin345
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.