STRINGSTRING
pyrH pyrH pyrD pyrD ABF39734.1 ABF39734.1 ABF40127.1 ABF40127.1 pyrE pyrE dcd dcd ABF40822.1 ABF40822.1 ABF40980.1 ABF40980.1 ABF41186.1 ABF41186.1 carA carA carB carB pyrF pyrF ABF42055.1 ABF42055.1 ABF42056.1 ABF42056.1 cmk cmk tmk tmk pyrG pyrG ABF42820.1 ABF42820.1 ABF42825.1 ABF42825.1 ndk ndk pyrC pyrC pyrR pyrR pyrB pyrB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (239 aa)
pyrDDihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (321 aa)
ABF39734.1Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (334 aa)
ABF40127.1Ribonucleoside-diphosphate reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1004 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (195 aa)
dcddCTP deaminase; Catalyzes the deamination of dCTP to dUTP. (184 aa)
ABF40822.1Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (319 aa)
ABF40980.1Deoxyuridine 5'-triphosphate nucleotidohydrolase (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (138 aa)
ABF41186.1MazG family protein. (405 aa)
carACarbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (373 aa)
carBCarbamoyl-phosphate synthase large subunit. (1102 aa)
pyrFOrotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (234 aa)
ABF42055.1Uridine kinase; Belongs to the uridine kinase family. (201 aa)
ABF42056.1Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (280 aa)
cmkCytidylate kinase. (227 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (217 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (558 aa)
ABF42820.1Protein of unknown function DUF201. (343 aa)
ABF42825.1Thymidylate kinase-like protein. (228 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (429 aa)
pyrRUracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (174 aa)
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (303 aa)
Your Current Organism:
Koribacter versatilis
NCBI taxonomy Id: 204669
Other names: Acidobacteria bacterium Ellin345, C. Koribacter versatilis Ellin345, Candidatus Koribacter versatilis Ellin345, Koribacter versatilis Ellin345, bacterium Ellin345
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