node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HEAR0648 | HEAR0919 | HEAR0648 | HEAR0919 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Putative fumarate hydratase class I, aerobic (Fumarase) (FumA-like); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.962 |
HEAR0648 | HEAR3327 | HEAR0648 | HEAR3327 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; Function of strongly homologous gene; enzyme. | 0.496 |
HEAR0648 | HEAR3329 | HEAR0648 | HEAR3329 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Putative fumarate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.425 |
HEAR0648 | HEAR3333 | HEAR0648 | HEAR3333 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Putative succinate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.718 |
HEAR0648 | acnA | HEAR0648 | HEAR1783 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Aconitate hydratase (Citrate hydro-lyase) (Aconitase); Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.413 |
HEAR0648 | fumC | HEAR0648 | HEAR2526 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Fumarate hydratase class II (fumarase C); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.970 |
HEAR0648 | gabD | HEAR0648 | HEAR2670 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Succinate-semialdehyde dehydrogenase [NADP+] (SSDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.606 |
HEAR0648 | gltA | HEAR0648 | HEAR1773 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family. | 0.929 |
HEAR0648 | mdh | HEAR0648 | HEAR1780 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.970 |
HEAR0648 | sdhA | HEAR0648 | HEAR1776 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Succinate dehydrogenase, flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.718 |
HEAR0648 | sdhB | HEAR0648 | HEAR1775 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Succinate dehydrogenase (ubiquinone), Fe-S protein; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.496 |
HEAR0648 | sdhC | HEAR0648 | HEAR1778 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Succinate dehydrogenase cytochrome b556 subunit (Cytochrome b-556); Function of strongly homologous gene; membrane component. | 0.425 |
HEAR0648 | sdhD | HEAR0648 | HEAR1777 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Succinate dehydrogenase hydrophobic membrane anchor subunit; Function of strongly homologous gene; membrane component. | 0.426 |
HEAR0648 | sucC | HEAR0648 | HEAR0343 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.660 |
HEAR0648 | sucD | HEAR0648 | HEAR0344 | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | Succinyl-CoA ligase [ADP-forming] subunit alpha (Succinyl-CoA synthetase subunit alpha) (SCS-alpha); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.521 |
HEAR0919 | HEAR0648 | HEAR0919 | HEAR0648 | Putative fumarate hydratase class I, aerobic (Fumarase) (FumA-like); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the malic enzymes family. | 0.962 |
HEAR0919 | HEAR3327 | HEAR0919 | HEAR3327 | Putative fumarate hydratase class I, aerobic (Fumarase) (FumA-like); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; Function of strongly homologous gene; enzyme. | 0.983 |
HEAR0919 | HEAR3328 | HEAR0919 | HEAR3328 | Putative fumarate hydratase class I, aerobic (Fumarase) (FumA-like); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Putative fumarate reductase respiratory complex transmembrane subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.973 |
HEAR0919 | HEAR3329 | HEAR0919 | HEAR3329 | Putative fumarate hydratase class I, aerobic (Fumarase) (FumA-like); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Putative fumarate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.967 |
HEAR0919 | HEAR3333 | HEAR0919 | HEAR3333 | Putative fumarate hydratase class I, aerobic (Fumarase) (FumA-like); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Putative succinate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.990 |