STRINGSTRING
HEAR0140 HEAR0140 HEAR0141 HEAR0141 HEAR0142 HEAR0142 glnK glnK amtB amtB HEAR0524 HEAR0524 glnE glnE glnA glnA glnL glnL glnG glnG glnB glnB glnD glnD HEAR1599 HEAR1599 HEAR2441 HEAR2441
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HEAR0140Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (119 aa)
HEAR0141Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (81 aa)
HEAR0142Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (244 aa)
glnKNitrogen regulatory protein P-II 2; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family. (112 aa)
amtBAmmonia channel precursor (Ammonia transporter); Function of homologous gene experimentally demonstrated in an other organism; transporter. (466 aa)
HEAR0524Putative Nitrogen regulatory protein P-II, glnB-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (113 aa)
glnEBifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...] (906 aa)
glnAGlutamine synthetase (Glutamate--ammonia ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (469 aa)
glnLNitrogen regulation protein NR(II); Function of homologous gene experimentally demonstrated in an other organism; regulator. (357 aa)
glnGNitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (510 aa)
glnBNitrogen regulatory protein P-II; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family. (112 aa)
glnD[Protein-PII] uridylyltransferase (PII uridylyl-transferase) (Uridylyl-removing enzyme) (UTase); Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regul [...] (850 aa)
HEAR1599Putative Nitrogen regulatory protein P-II, glnB-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (113 aa)
HEAR2441Putative ammonium transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (400 aa)
Your Current Organism:
Herminiimonas arsenicoxydans
NCBI taxonomy Id: 204773
Other names: CCM 7303, DSM 17148, H. arsenicoxydans, Herminiimonas arsenicoxydans Muller et al. 2006, LMG 22961, LMG:22961, strain ULPAs1
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