STRINGSTRING
aoxD aoxD aoxC aoxC aoxB aoxB aoxA aoxA aoxS aoxS aoxR aoxR nirM nirM HEAR0823 HEAR0823 HEAR1115 HEAR1115 coxN coxN HEAR1117 HEAR1117 coxP coxP HEAR1119 HEAR1119 HEAR1482 HEAR1482 nuoN nuoN nuoM nuoM nuoL nuoL nuoK nuoK nuoJ nuoJ nuoI nuoI nuoH nuoH nuoG nuoG nuoF nuoF nuoE nuoE nuoD nuoD nuoC nuoC nuoB nuoB nuoA nuoA acpP acpP fdxA3 fdxA3 HEAR2640 HEAR2640 HEAR2696 HEAR2696 HEAR2697 HEAR2697 HEAR2698 HEAR2698 cyoD cyoD cyoC cyoC cyoB cyoB cyoA cyoA HEAR2703 HEAR2703 fdx2 fdx2 HEAR2902 HEAR2902 HEAR2903 HEAR2903 HEAR2915 HEAR2915 ctaD ctaD ctaC ctaC petC petC petB petB petA petA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aoxDCytochrome c-552 precursor (Cytochrome c552); Function of strongly homologous gene; carrier. (105 aa)
aoxCPutative nitroreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (203 aa)
aoxBArsenite oxidase large subunit (AOI); Involved in the detoxification of arsenic. Oxidizes As(III)O3(3-) (arsenite) to the somewhat less toxic As(V)O4(3-) (arsenate); Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (826 aa)
aoxAArsenite oxidase small subunit precursor, Rieske type subunit, twin arginine translocation peptide; Involved in the detoxification of arsenic. Oxidizes As(III)O3(3-) (arsenite) to the somewhat less toxic As(V)O4(3-) (arsenate); Belongs to the AOX family. (173 aa)
aoxSSignal transduction protein involved in AoxAB regulation (AoxS); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (479 aa)
aoxRAoxR regulatory protein; Function of homologous gene experimentally demonstrated in an other organism; regulator. (454 aa)
nirMCytochrome c-551 precursor (Cytochrome c551) (Cytochrome C8); Function of homologous gene experimentally demonstrated in an other organism; carrier. (102 aa)
HEAR0823Cytochrome c2; Function of homologous gene experimentally demonstrated in an other organism; carrier. (122 aa)
HEAR1115Putative Cytochrome c oxidase, subunit II (Cytochrome bb3 subunit 2) CoxM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (400 aa)
coxNCytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (586 aa)
HEAR1117Putative cytochrome c oxidase subunit III CoxO; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (216 aa)
coxPCytochrome-c oxidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (230 aa)
HEAR1119Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (105 aa)
HEAR1482Function of homologous gene experimentally demonstrated in an other organism; carrier. (136 aa)
nuoNNADH-ubiquinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (494 aa)
nuoMNADH-quinone oxidoreductase subunit M; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (496 aa)
nuoLNADH-quinone oxidoreductase subunit L (NADH dehydrogenase I subunit L) (NDH-1 subunit L); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (687 aa)
nuoKNADH-quinone oxidoreductase subunit K (NADH dehydrogenase I subunit K) (NDH-1 subunit K); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (102 aa)
nuoJNADH-quinone oxidoreductase subunit J (NADH dehydrogenase I subunit J) (NDH-1 subunit J); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (213 aa)
nuoINADH-quinone oxidoreductase subunit I (NADH dehydrogenase I subunit I) (NDH-1 subunit I); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (162 aa)
nuoHNADH-quinone oxidoreductase subunit H (NADH dehydrogenase I subunit H) (NDH-1 subunit H); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (357 aa)
nuoGNADH-quinone oxidoreductase subunit G (NADH dehydrogenase I subunit G) (NDH-1 subunit G); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (777 aa)
nuoFNADH-quinone oxidoreductase subunit F (NADH dehydrogenase I subunit F) (NDH-1 subunit F); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (431 aa)
nuoENADH-quinone oxidoreductase subunit E (NADH dehydrogenase I subunit E) (NDH-1 subunit E); Function of strongly homologous gene; enzyme. (159 aa)
nuoDNADH-ubiquinone oxidoreductase D subunit (NADH dehydrogenase subunit D); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (417 aa)
nuoCNADH-quinone oxidoreductase chain C (NADH dehydrogenase I, chain C) (NDH-1, chain C); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. (198 aa)
nuoBNADH-quinone oxidoreductase subunit B (NADH dehydrogenase I subunit B) (NDH-1 subunit B); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity). (158 aa)
nuoANADH-quinone oxidoreductase chain A (NADH dehydrogenase I, chain A) (NDH-1, chain A); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (119 aa)
acpPAcyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (80 aa)
fdxA3Ferredoxin 1; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (116 aa)
HEAR2640Deoxynucleoside kinase; Function of strongly homologous gene; enzyme. (213 aa)
HEAR2696Putative two-component response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (178 aa)
HEAR2697Putative two-component sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (449 aa)
HEAR2698Conserved hypothetical protein, putative cytochrome c biogenesis; Homologs of previously reported genes of unknown function. (265 aa)
cyoDCytochrome o ubiquinol oxidase protein CyoD (Ubiquinol oxidase chain D); Function of homologous gene experimentally demonstrated in an other organism; carrier. (136 aa)
cyoCCytochrome o ubiquinol oxidase subunit 3 (Cytochrome o ubiquinol oxidase subunit III); Function of homologous gene experimentally demonstrated in an other organism; carrier. (214 aa)
cyoBCytochrome o ubiquinol oxidase subunit I; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the heme-copper respiratory oxidase family. (667 aa)
cyoAUbiquinol oxidase subunit 2; Function of homologous gene experimentally demonstrated in an other organism; carrier. (355 aa)
HEAR2703Putative membrane transport protein, MFS family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (449 aa)
fdx2Ferredoxin; Function of homologous gene experimentally demonstrated in an other organism; carrier. (87 aa)
HEAR2902Putative peptidase M16; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (436 aa)
HEAR2903Putative peptidase M16; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (427 aa)
HEAR2915Cytochrome c oxidase polypeptide III; Function of strongly homologous gene; carrier. (288 aa)
ctaDCytochrome c oxidase subunit 1 (Cytochrome c oxidase polypeptide I) (Cytochrome aa3 subunit 1); Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (533 aa)
ctaCCytochrome c oxidase, subunit II (Cytochrome aa3 subunit 2); Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (386 aa)
petCCytochrome c1 precursor; Function of strongly homologous gene; carrier. (254 aa)
petBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (467 aa)
petAUbiquinol-cytochrome c reductase iron-sulfur subunit (Rieske iron-sulfur protein) (RISP); Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (202 aa)
Your Current Organism:
Herminiimonas arsenicoxydans
NCBI taxonomy Id: 204773
Other names: CCM 7303, DSM 17148, H. arsenicoxydans, Herminiimonas arsenicoxydans Muller et al. 2006, LMG 22961, LMG:22961, strain ULPAs1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.