STRINGSTRING
recJ recJ rnpA rnpA tesB tesB arsC1 arsC1 HEAR3218 HEAR3218 arsC4 arsC4 HEAR3119 HEAR3119 HEAR3116 HEAR3116 HEAR3105 HEAR3105 uvrA2 uvrA2 HEAR3085 HEAR3085 HEAR3043 HEAR3043 HEAR3042 HEAR3042 cca cca pth pth HEAR2860 HEAR2860 proS proS HEAR2759 HEAR2759 HEAR2757 HEAR2757 HEAR2755 HEAR2755 HEAR2739 HEAR2739 leuS leuS HEAR2629 HEAR2629 HEAR2621 HEAR2621 gph gph HEAR2548 HEAR2548 HEAR2511 HEAR2511 xseA xseA HEAR2477 HEAR2477 HEAR2403 HEAR2403 HEAR2385 HEAR2385 HEAR2373 HEAR2373 gloB gloB rnhA rnhA dnaQ dnaQ HEAR2308 HEAR2308 HEAR2293 HEAR2293 HEAR2264 HEAR2264 HEAR2262 HEAR2262 uvrB2 uvrB2 dnaN dnaN HEAR0008 HEAR0008 HEAR0009 HEAR0009 HEAR0049 HEAR0049 HEAR0098 HEAR0098 HEAR0113 HEAR0113 HEAR0136 HEAR0136 HEAR0161 HEAR0161 HEAR0201 HEAR0201 HEAR0216 HEAR0216 HEAR0222 HEAR0222 dtd dtd ruvC ruvC valS valS polA polA xseB xseB HEAR0374 HEAR0374 ybeY ybeY HEAR0422 HEAR0422 HEAR0423 HEAR0423 HEAR0435 HEAR0435 HEAR0446 HEAR0446 dnaE dnaE HEAR0469 HEAR0469 HEAR0496 HEAR0496 arsC2a arsC2a HEAR0513 HEAR0513 HEAR0514 HEAR0514 cafA cafA fbp1 fbp1 HEAR0580 HEAR0580 sbcB sbcB ugpQ ugpQ HEAR0636 HEAR0636 pgpA pgpA HEAR0649 HEAR0649 HEAR0655 HEAR0655 HEAR0659 HEAR0659 dnaE2 dnaE2 HEAR0688 HEAR0688 HEAR0707 HEAR0707 HEAR0708 HEAR0708 HEAR0752 HEAR0752 ileS ileS glnE glnE orn orn HEAR0913 HEAR0913 HEAR0917 HEAR0917 HEAR0953 HEAR0953 HEAR1016 HEAR1016 frmC frmC HEAR1105 HEAR1105 phoR2 phoR2 HEAR1195 HEAR1195 HEAR1245 HEAR1245 HEAR1251 HEAR1251 surE surE rnr rnr cheB cheB cheZ cheZ HEAR1309 HEAR1309 glnD glnD rnhB rnhB HEAR1382 HEAR1382 HEAR1391 HEAR1391 HEAR1400 HEAR1400 HEAR1476 HEAR1476 HEAR1498 HEAR1498 HEAR1512 HEAR1512 bioH bioH HEAR1696 HEAR1696 HEAR1715 HEAR1715 tesA tesA vsr vsr HEAR1842 HEAR1842 HEAR1850 HEAR1850 HEAR1851 HEAR1851 serB serB HEAR1936 HEAR1936 arsC3b arsC3b HEAR2029 HEAR2029 uvrA1 uvrA1 frmB frmB uvrB1 uvrB1 uvrC1 uvrC1 rnc rnc HEAR2086 HEAR2086 rne rne rph rph HEAR2127 HEAR2127 HEAR2129 HEAR2129 HEAR2134 HEAR2134 suhB suhB HEAR2211 HEAR2211 HEAR2222 HEAR2222
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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recJSingle-stranded-DNA-specific exonuclease RecJ; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (564 aa)
rnpAPutative ribonuclease P rnpA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (136 aa)
tesBacyl-CoA thioesterase II; Function of strongly homologous gene; enzyme. (291 aa)
arsC1Arsenate reductase; Function experimentally demonstrated in the studied strain; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (166 aa)
HEAR3218Conserved hypothetical protein, putative restriction endonuclease; Homologs of previously reported genes of unknown function. (362 aa)
arsC4Arsenate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (168 aa)
HEAR3119Deoxyguanosinetriphosphate triphosphohydrolase; Function of strongly homologous gene; enzyme; Belongs to the dGTPase family. Type 2 subfamily. (382 aa)
HEAR3116Putative Type II secretory pathway, pseudopilin PulG; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (148 aa)
HEAR3105Putative 3-Deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P phosphatase) kdsC-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (179 aa)
uvrA2UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (954 aa)
HEAR3085Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (563 aa)
HEAR3043Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (359 aa)
HEAR3042Putative thermonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (147 aa)
cca2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (414 aa)
pthpeptidyl-tRNA hydrolase (PTH); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (196 aa)
HEAR2860Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (162 aa)
proSProlyl-tRNA synthetase (Proline--tRNA ligase) (ProRS) (Global RNA synthesis factor); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other a [...] (577 aa)
HEAR2759Conserved hypothetical protein, putative nucleotidyltransferase domain; Homologs of previously reported genes of unknown function. (206 aa)
HEAR2757Putative alpha/beta-hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (194 aa)
HEAR2755Putative exoribonuclease II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (675 aa)
HEAR2739Putative holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (131 aa)
leuSLeucyl-tRNA synthetase (Leucine--tRNA ligase) (LeuRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (881 aa)
HEAR2629Hypothetical protein, putative ribonuclease H domain; No homology to any previously reported sequences. (222 aa)
HEAR2621Putative protein serine/threonine phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (276 aa)
gphPhosphoglycolate phosphatase (PGPase) (PGP); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (221 aa)
HEAR2548Putative metal-dependent phosphohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (198 aa)
HEAR2511Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (100 aa)
xseAExodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (453 aa)
HEAR2477Guanine-specific ribonuclease N1 and T1; Function of strongly homologous gene; enzyme. (124 aa)
HEAR2403Putative thioesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (141 aa)
HEAR2385Putative exodeoxyribonuclease III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (254 aa)
HEAR2373Putative Tfp pilus assembly protein FimT; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. (167 aa)
gloBPutative hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) GloB-like; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (259 aa)
rnhARibonuclease HI (RNase HI); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (146 aa)
dnaQDNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (234 aa)
HEAR2308Putative phage-related exodeoxyribonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (211 aa)
HEAR2293Putative bacteriophage Lambda NinG; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (194 aa)
HEAR2264Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (268 aa)
HEAR2262Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (897 aa)
uvrB2UvrABC system protein B (Protein uvrB) (Excinuclease ABC subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesi [...] (694 aa)
dnaNDNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (368 aa)
HEAR0008Putative restriction endonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (265 aa)
HEAR0009Putative restriction endonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (306 aa)
HEAR0049Putative membrane-associated metal-dependent hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (571 aa)
HEAR0098Putative Metallo-beta-lactamase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (354 aa)
HEAR0113Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (267 aa)
HEAR0136Putative 5'-3' exonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (261 aa)
HEAR0161Putative Nuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (259 aa)
HEAR0201Putative Phosphoglycolate phosphatase (PGP) (gph); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (209 aa)
HEAR0216Putative gluconolactonase with senescence marker; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (296 aa)
HEAR0222Acyl-CoA thioester hydrolase; Function of strongly homologous gene; enzyme. (138 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (149 aa)
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (180 aa)
valSValyl-tRNA synthetase (Valine--tRNA ligase) (ValRS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (969 aa)
polADNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (917 aa)
xseBExodeoxyribonuclease VII small subunit (Exonuclease VII small subunit) (XseB); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (84 aa)
HEAR0374Putative histidinol-phosphate phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (185 aa)
ybeYPutative metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (156 aa)
HEAR0422Putative DNase I-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (337 aa)
HEAR0423Putative prolyl-tRNA synthetase associated; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (163 aa)
HEAR0435Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (457 aa)
HEAR0446Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (399 aa)
dnaEDNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1153 aa)
HEAR0469Putative nuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (105 aa)
HEAR0496Putative serine phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (420 aa)
arsC2aArsenate reductase; Function experimentally demonstrated in the studied strain; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (171 aa)
HEAR0513Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (300 aa)
HEAR0514Conserved hypothetical protein, putative phage-related; Homologs of previously reported genes of unknown function. (333 aa)
cafARNase G (ribonuclease G); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (487 aa)
fbp1Fructose-1,6-bisphosphatase (D-fructose-1, 6-bisphosphate 1-phosphohydrolase) (FBPase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (334 aa)
HEAR0580Putative DNA-polymerase/ribonuclease/exonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (193 aa)
sbcBExodeoxyribonuclease I (Exonuclease I) (DNA deoxyribophosphodiesterase) (dRPase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (477 aa)
ugpQGlycerophosphodiester phosphodiesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (256 aa)
HEAR0636Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (267 aa)
pgpAPhosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (193 aa)
HEAR0649Putative 5'-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (309 aa)
HEAR0655Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (783 aa)
HEAR0659Transposase IS21 family (partial); Gene remnant; extrachromosomal origin. (40 aa)
dnaE2Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1045 aa)
HEAR0688Putative MobA/MobL family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (239 aa)
HEAR0707Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (854 aa)
HEAR0708Putative ATP-dependent exoDNAse (exonuclease V) beta subunit RecB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1096 aa)
HEAR0752Putative lipase/esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (204 aa)
ileSIsoleucine tRNA synthetase (Isoleucine--tRNA ligase) (IleRS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (959 aa)
glnEBifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...] (906 aa)
ornOligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family. (198 aa)
HEAR0913Hypothetical protein; No homology to any previously reported sequences. (96 aa)
HEAR0917Putative Hydroxyacylglutathione hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (249 aa)
HEAR0953Putative chemotaxis phosphatase, CheZ-like; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). (253 aa)
HEAR1016Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (222 aa)
frmCS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (280 aa)
HEAR1105Putative phosphohistidine phosphatase sixA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (156 aa)
phoR2Phosphate regulon sensor protein PhoR; Function of homologous gene experimentally demonstrated in an other organism; receptor. (430 aa)
HEAR1195Putative sulfur oxidation protein SoxB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. (572 aa)
HEAR1245Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (715 aa)
HEAR1251Putative Serine/threonine protein phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (268 aa)
surE5'-nucleotidase SurE (Nucleoside 5'-monophosphate phosphohydrolase); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (245 aa)
rnrRNase R, 3'-5' exoribonuclease; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (820 aa)
cheBChemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (358 aa)
cheZChemotaxis protein CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P). (212 aa)
HEAR1309Conserved hypothetical protein, putative EAL and modified HD-GYP domains; Homologs of previously reported genes of unknown function. (402 aa)
glnD[Protein-PII] uridylyltransferase (PII uridylyl-transferase) (Uridylyl-removing enzyme) (UTase); Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regul [...] (850 aa)
rnhBRibonuclease HII (RNase HII); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (211 aa)
HEAR1382Putative alpha/beta-Hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (199 aa)
HEAR1391Putative Phenylacetic acid degradation thioesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (148 aa)
HEAR1400Putative Mg-dependent DNase, TatD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (259 aa)
HEAR1476Putative 5'-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. (596 aa)
HEAR1498Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (70 aa)
HEAR1512Putative exonuclease, metallo-beta-lactamase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (453 aa)
bioHCarboxylesterase BioH (Biotin synthesis protein BioH); Function of strongly homologous gene; enzyme. (245 aa)
HEAR1696Conserved hypothetical protein, induce by arsenic; Homologs of previously reported genes of unknown function. (780 aa)
HEAR1715Conserved hypothetical protein, putative restriction endonuclease; Homologs of previously reported genes of unknown function. (205 aa)
tesAAcyl-CoA thioesterase I precursor (Protease I) (Lysophospholipase L1) (Lecithinase B); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (216 aa)
vsrVery short patch repair protein (DNA mismatch endonuclease) (Vsr mismatch endonuclease); May nick specific sequences that contain T:G mispairs resulting from m5C-deamination. (152 aa)
HEAR1842Putative restriction endonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (269 aa)
HEAR1850Conserved hypothetical protein, putative phage-related; Homologs of previously reported genes of unknown function. (333 aa)
HEAR1851Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (303 aa)
serBPhosphoserine phosphatase (PSP) (O-phosphoserine phosphohydrolase) (PSPase); Function of strongly homologous gene; enzyme. (281 aa)
HEAR1936Conserved hypothetical protein, putative PIN domain; Homologs of previously reported genes of unknown function. (161 aa)
arsC3bArsenate reductase; Function experimentally demonstrated in the studied strain; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (164 aa)
HEAR2029Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (152 aa)
uvrA1UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (883 aa)
frmBS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (276 aa)
uvrB1UvrABC system protein B (Protein uvrB) (Excinuclease ABC subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesi [...] (658 aa)
uvrC1UvrABC system protein C (Protein uvrC) (Excinuclease ABC subunit C); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (618 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (328 aa)
HEAR2086Putative phosphoglycolate phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (219 aa)
rneRibonuclease E (RNase E); Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (973 aa)
rphRibonuclease PH (RNase PH) (tRNA nucleotidyltransferase); Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (244 aa)
HEAR2127Putative serine/threonine specific protein phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (309 aa)
HEAR2129Conserved hypothetical protein, putative stress-induced protein; Homologs of previously reported genes of unknown function. (300 aa)
HEAR2134Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (425 aa)
suhBInositol-1-monophosphatase (IMPase) (Inositol-1-phosphatase) (I-1-Pase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the inositol monophosphatase superfamily. (261 aa)
HEAR2211Conserved hypothetical protein, putative regulator of chromosome condensation; Homologs of previously reported genes of unknown function. (500 aa)
HEAR2222TatD-related deoxyribonuclease; Function of strongly homologous gene; enzyme. (265 aa)
Your Current Organism:
Herminiimonas arsenicoxydans
NCBI taxonomy Id: 204773
Other names: CCM 7303, DSM 17148, H. arsenicoxydans, Herminiimonas arsenicoxydans Muller et al. 2006, LMG 22961, LMG:22961, strain ULPAs1
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