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| | HEAR0644 | Putative rubredoxin-NAD(+) reductase NorW-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (403 aa) |
| | mtnN | 5'-Methylthioadenosine/S-adenosylhomocysteine (SAH) nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (262 aa) |
| | HEAR3395 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (170 aa) |
| | ectD | Ectoine hydroxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (306 aa) |
| | HEAR3371 | Conserved hypothetical protein, putative SlyX domain; Homologs of previously reported genes of unknown function. (68 aa) |
| | uxaA | Altronate dehydratase; Function of strongly homologous gene; enzyme. (389 aa) |
| | HEAR3336 | Altronate dehydratase (N part); Function of strongly homologous gene; enzyme. (93 aa) |
| | HEAR3315 | Putative deoxygenases; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (263 aa) |
| | HEAR3312 | Putative 2,5-didehydrogluconate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (277 aa) |
| | HEAR3277 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (124 aa) |
| | HEAR3273 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (115 aa) |
| | HEAR3260 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (164 aa) |
| | amaB | N-carbamoyl-L-amino acid hydrolase (L-carbamoylase); Function of strongly homologous gene; enzyme. (432 aa) |
| | deaD | Putative ATP-dependent RNA helicase DeaD-like; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (826 aa) |
| | HEAR3119 | Deoxyguanosinetriphosphate triphosphohydrolase; Function of strongly homologous gene; enzyme; Belongs to the dGTPase family. Type 2 subfamily. (382 aa) |
| | HEAR3061 | Histidine triad (HIT) protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (124 aa) |
| | HEAR2996 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (383 aa) |
| | HEAR2951 | Putative carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (317 aa) |
| | HEAR2897 | Putative molybdopterin cofactor sulfurase-related; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (283 aa) |
| | HEAR2838 | Putative butyryl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (596 aa) |
| | HEAR2837 | Putative bifunctionnal protein 3-hydroxyacyl-CoA dehydrogenase and dodecenoyl-CoA isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (799 aa) |
| | rppH | Putative (di)nucleoside polyphosphate hydrolase NudH-like; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (193 aa) |
| | HEAR2759 | Conserved hypothetical protein, putative nucleotidyltransferase domain; Homologs of previously reported genes of unknown function. (206 aa) |
| | HEAR2724 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (380 aa) |
| | HEAR2678 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (233 aa) |
| | HEAR2674 | Putative gamma-glutamyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (565 aa) |
| | HEAR2667 | Putative DSBA oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (200 aa) |
| | HEAR2636 | Putative hydrolase, haloacid dehalogenase-like family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (224 aa) |
| | HEAR2629 | Hypothetical protein, putative ribonuclease H domain; No homology to any previously reported sequences. (222 aa) |
| | HEAR2542 | Putative nitroreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (188 aa) |
| | xseA | Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (453 aa) |
| | HEAR2479 | Putative gamma-glutamyltranspeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (597 aa) |
| | HEAR2460 | Gamma-glutamyltransferase; Function of strongly homologous gene; enzyme. (531 aa) |
| | bpt | Putative arginyl-tRNA--protein transferase (R-transferase) (Arginyltransferase) Ate-like; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily. (241 aa) |
| | HEAR2328 | Putative ATP-dependent RNA helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DEAD box helicase family. (468 aa) |
| | gloB | Putative hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) GloB-like; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (259 aa) |
| | rnhA | Ribonuclease HI (RNase HI); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (146 aa) |
| | HEAR2266 | Putative phage lysozyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (147 aa) |
| | HEAR2182 | Putative alpha/beta hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (290 aa) |
| | rhlE2 | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (449 aa) |
| | putA | Bifunctional protein putA: Proline dehydrogenase (Proline oxidase); Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1224 aa) |
| | HEAR2129 | Conserved hypothetical protein, putative stress-induced protein; Homologs of previously reported genes of unknown function. (300 aa) |
| | rph | Ribonuclease PH (RNase PH) (tRNA nucleotidyltransferase); Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (244 aa) |
| | HEAR2125 | HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (194 aa) |
| | HEAR2098 | Putative phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (238 aa) |
| | rne | Ribonuclease E (RNase E); Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (973 aa) |
| | frmB | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (276 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase (Polynucleotide phosphorylase) (PNPase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (710 aa) |
| | phaZ3 | Poly(3-hydroxybutyrate) depolymerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (269 aa) |
| | sucB | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (414 aa) |
| | dadA2 | D-amino acid dehydrogenase, small subunit; Function of strongly homologous gene; enzyme. (414 aa) |
| | HEAR1741 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (134 aa) |
| | HEAR1696 | Conserved hypothetical protein, induce by arsenic; Homologs of previously reported genes of unknown function. (780 aa) |
| | dbpA | ATP-dependent RNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DEAD box helicase family. (464 aa) |
| | HEAR1507 | Putative alpha/beta-Hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (230 aa) |
| | HEAR1476 | Putative 5'-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. (596 aa) |
| | mdcA | Malonate decarboxylase, alpha subunit; Function of strongly homologous gene; enzyme. (550 aa) |
| | nemA | N-ethylmaleimide reductase, FMN-linked; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (352 aa) |
| | HEAR1383 | Putative alpha/beta hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (305 aa) |
| | HEAR1371 | Putative cytochrome c precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (165 aa) |
| | rnhB | Ribonuclease HII (RNase HII); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (211 aa) |
| | surE | 5'-nucleotidase SurE (Nucleoside 5'-monophosphate phosphohydrolase); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (245 aa) |
| | katA | Catalase (hydroperoxidase II); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the catalase family. (478 aa) |
| | HEAR1199 | Putative fumarylacetoacetate (FAA) hydrolase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (264 aa) |
| | HEAR1195 | Putative sulfur oxidation protein SoxB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. (572 aa) |
| | HEAR1185 | Putative Beta lactamase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (323 aa) |
| | HEAR1181 | Conserved hypothetical protein, putative xanthine dehydrogenase; Homologs of previously reported genes of unknown function. (355 aa) |
| | iorB | Isoquinoline 1-oxidoreductase, beta subunit; Function of strongly homologous gene; enzyme. (779 aa) |
| | iorA | Isoquinoline 1-oxidoreductase alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (196 aa) |
| | edd | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (637 aa) |
| | frmC | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (280 aa) |
| | aidB | Isovaleryl CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (551 aa) |
| | HEAR0995 | Carboxylesterase; Function of strongly homologous gene; enzyme. (220 aa) |
| | fpr | ferredoxin--NADP+ reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (259 aa) |
| | HEAR0913 | Hypothetical protein; No homology to any previously reported sequences. (96 aa) |
| | HEAR0911 | Conserved hypothetical protein, putative pyrophosphatase; Homologs of previously reported genes of unknown function. (109 aa) |
| | HEAR0851 | Putative fumarylacetoacetate (FAA) hydrolase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (229 aa) |
| | coaB | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (396 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (dUTP pyrophosphatase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (149 aa) |
| | HEAR0798 | Putative NADH dehydrogenase/NAD(P)H nitroreductase RutE (Pyrimidine utilization protein E); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (205 aa) |
| | dehH | Haloacetate dehalogenase; Function of strongly homologous gene; enzyme. (308 aa) |
| | dadA1 | D-amino acid dehydrogenase small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (443 aa) |
| | HEAR0672 | Putative Nitroreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (200 aa) |
| | fadE | Acyl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (596 aa) |
| | HEAR0614 | Gamma-glutamyltranspeptidase; Function of strongly homologous gene; enzyme. (532 aa) |
| | blaA | Class A beta-lactamase precursor (Penicillinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (299 aa) |
| | HEAR0601 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (271 aa) |
| | rhlE1 | ATP-dependent RNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DEAD box helicase family. (502 aa) |
| | nasD | Nitrite reductase [NAD(P)H], large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (809 aa) |
| | HEAR0400 | Putative metal dependent amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (581 aa) |
| | HEAR0385 | Putative enzyme involved in biosynthesis of extracellular polysaccharides; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (115 aa) |
| | gloA | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (139 aa) |
| | HEAR0360 | Putative D-amino acid dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (442 aa) |
| | glxR | 2-hydroxy-3-oxopropionate reductase (Tartronate semialdehyde reductase) (TSAR); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (295 aa) |
| | gcl | Glyoxylate carboligase (Tartronate-semialdehyde synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TPP enzyme family. (582 aa) |
| | xseB | Exodeoxyribonuclease VII small subunit (Exonuclease VII small subunit) (XseB); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (84 aa) |
| | HEAR0270 | Putative carboxymethylenebutenolidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (294 aa) |
| | HEAR0260 | Putative 2-keto-4-pentenoate hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (280 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (149 aa) |
| | anmK | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (379 aa) |
| | HEAR0217 | Putative 2-hydroxy-3-oxopropionate reductase glxR-like (Tartronate semialdehyde reductase) (TSAR); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (287 aa) |
| | glpK | Glycerol kinase (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (498 aa) |
| | mvaB | Hydroxymethylglutaryl-CoA lyase (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (305 aa) |
| | HEAR0098 | Putative Metallo-beta-lactamase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (354 aa) |
| | HEAR0067 | Putative enzyme involved in biosynthesis of extracellular polysaccharides; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (100 aa) |
