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aptA aptA fabI fabI plsX plsX fabH1 fabH1 fabD1 fabD1 acpP acpP bioA bioA bioD bioD bioB bioB HEAR0201 HEAR0201 panD panD HEAR0340 HEAR0340 abpA abpA panC panC accD accD accA accA fabZ fabZ mdcC mdcC mdcB mdcB HEAR1475 HEAR1475 bioF bioF bioH bioH bioC bioC fabF1 fabF1 acpS acpS ectA ectA ectC ectC HEAR3266 HEAR3266 lipA lipA bioC-2 bioC-2 HEAR2876 HEAR2876 HEAR2875 HEAR2875 HEAR2865 HEAR2865 HEAR2863 HEAR2863 accC accC accB accB ubiC ubiC panB panB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
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gene neighborhood
gene fusions
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aptAOmega-amino acid:pyruvate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (440 aa)
fabIEnoyl-[acyl-carrier-protein] reductase [NADH] (NADH-dependent enoyl-ACP reductase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (261 aa)
plsXFatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (357 aa)
fabH13-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (328 aa)
fabD1malonyl-CoA-[acyl-carrier-protein] transacylase (MCT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (310 aa)
acpPAcyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (80 aa)
bioAAdenosylmethionine---8-amino-7-oxononanoate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
bioDDethiobiotin synthetase (Dethiobiotin synthase) (DTB synthetase) (DTBS); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (250 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (339 aa)
HEAR0201Putative Phosphoglycolate phosphatase (PGP) (gph); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (209 aa)
panDAspartate 1-decarboxylase alpha chain; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (119 aa)
HEAR0340Zinc-binding dehydrogenase superfamily (quinone oxidoreductase, NADPH dependent); Function of strongly homologous gene; enzyme. (325 aa)
abpA2-dehydropantoate 2-reductase (Ketopantoate reductase) (KPA reductase) (KPR); Function of strongly homologous gene; enzyme. (336 aa)
panCPantoate--beta-alanine ligase (Pantothenate synthetase) (Pantoate-activating enzyme); Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (279 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (324 aa)
fabZ(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase ((3R)-hydroxymyristoyl ACP dehydrase); Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (156 aa)
mdcCMalonate decarboxylase, delta subunit; Function of strongly homologous gene; enzyme. (104 aa)
mdcBMalonate decarboxylase beta subunit MdcB; Function of strongly homologous gene; enzyme. (298 aa)
HEAR1475Putative malonyl CoA-ACP transacylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (315 aa)
bioF8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (388 aa)
bioHCarboxylesterase BioH (Biotin synthesis protein BioH); Function of strongly homologous gene; enzyme. (245 aa)
bioCPutative biotin synthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (260 aa)
fabF13-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (413 aa)
acpSHolo-[acyl-carrier-protein] synthase (CoA:apo-[acyl-carrier-protein] pantetheinephosphotransferase); Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (130 aa)
ectAL-2,4-diaminobutyric acid acetyltransferase (DABA acetyltransferase); Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (178 aa)
ectCL-ectoine synthase (N-acetyldiaminobutyrate dehydratase); Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (145 aa)
HEAR3266Putative methylisocitrate lyase (2-methylisocitrate lyase) (PrpB); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (293 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (335 aa)
bioC-2Putative S-adenosyl-L-methionine-dependent methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (319 aa)
HEAR28763-oxoacyl-[acyl-carrier-protein] synthase I; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (396 aa)
HEAR2875Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (268 aa)
HEAR2865Conserved hypothetical protein, putative dehydratase; Homologs of previously reported genes of unknown function. (96 aa)
HEAR2863Putative acyl carrier protein (ACP); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (96 aa)
accCBiotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (456 aa)
accBBiotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (153 aa)
ubiCPutative chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (193 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase (Ketopantoate hydroxymethyltransferase) (KPHMT); Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (276 aa)
Your Current Organism:
Herminiimonas arsenicoxydans
NCBI taxonomy Id: 204773
Other names: CCM 7303, DSM 17148, H. arsenicoxydans, Herminiimonas arsenicoxydans Muller et al. 2006, LMG 22961, LMG:22961, strain ULPAs1
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