node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HEAR2603 | HEAR2864 | HEAR2603 | HEAR2864 | Hypothetical protein; No homology to any previously reported sequences. | Putative 4-coumarate--CoA ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.549 |
HEAR2603 | acsA | HEAR2603 | HEAR0921 | Hypothetical protein; No homology to any previously reported sequences. | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.549 |
HEAR2603 | prpE | HEAR2603 | HEAR3269 | Hypothetical protein; No homology to any previously reported sequences. | Propionate--CoA ligase (Propionyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.549 |
HEAR2864 | HEAR2603 | HEAR2864 | HEAR2603 | Putative 4-coumarate--CoA ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Hypothetical protein; No homology to any previously reported sequences. | 0.549 |
HEAR2864 | fadD | HEAR2864 | HEAR0221 | Putative 4-coumarate--CoA ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Long-chain-fatty-acid--CoA ligase (Long-chain acyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.549 |
acsA | HEAR2603 | HEAR0921 | HEAR2603 | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Hypothetical protein; No homology to any previously reported sequences. | 0.549 |
acsA | fadD | HEAR0921 | HEAR0221 | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Long-chain-fatty-acid--CoA ligase (Long-chain acyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.671 |
acsA | prpE | HEAR0921 | HEAR3269 | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Propionate--CoA ligase (Propionyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.912 |
fadD | HEAR2864 | HEAR0221 | HEAR2864 | Long-chain-fatty-acid--CoA ligase (Long-chain acyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative 4-coumarate--CoA ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.549 |
fadD | acsA | HEAR0221 | HEAR0921 | Long-chain-fatty-acid--CoA ligase (Long-chain acyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.671 |
fadD | prpE | HEAR0221 | HEAR3269 | Long-chain-fatty-acid--CoA ligase (Long-chain acyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Propionate--CoA ligase (Propionyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.674 |
prpE | HEAR2603 | HEAR3269 | HEAR2603 | Propionate--CoA ligase (Propionyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Hypothetical protein; No homology to any previously reported sequences. | 0.549 |
prpE | acsA | HEAR3269 | HEAR0921 | Propionate--CoA ligase (Propionyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.912 |
prpE | fadD | HEAR3269 | HEAR0221 | Propionate--CoA ligase (Propionyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Long-chain-fatty-acid--CoA ligase (Long-chain acyl-CoA synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.674 |