STRINGSTRING
HEAR0251 HEAR0251 pyk pyk fbp1 fbp1 aceE aceE pdhB pdhB lpdA lpdA gap gap acsA acsA HEAR1070 HEAR1070 pgi pgi pps pps HEAR1610 HEAR1610 odhL odhL tpiA tpiA HEAR2039 HEAR2039 eno eno HEAR2367 HEAR2367 cbbA cbbA pgk pgk HEAR2721 HEAR2721 gpmA1 gpmA1 gpmA2 gpmA2 HEAR3352 HEAR3352
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HEAR0251Putative Phosphoglycerate/bisphosphoglycerate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the phosphoglycerate mutase family. (216 aa)
pykPyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. (471 aa)
fbp1Fructose-1,6-bisphosphatase (D-fructose-1, 6-bisphosphate 1-phosphohydrolase) (FBPase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (334 aa)
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (898 aa)
pdhBAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (455 aa)
lpdADihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (611 aa)
gapGlyceraldehyde 3-phosphate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
acsAAcetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
HEAR1070S-(hydroxymethyl)glutathione dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (368 aa)
pgiGlucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family. (549 aa)
ppsPhosphoenolpyruvate synthase (Pyruvate, water dikinase) (PEP synthase); Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (812 aa)
HEAR1610Zinc-containing alcohol dehydrogenase superfamily; Function of strongly homologous gene; enzyme. (352 aa)
odhLDihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (475 aa)
tpiATriosephosphate isomerase (TIM) (Triose-phosphate isomerase); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (248 aa)
HEAR2039S-(hydroxymethyl)glutathione dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa)
enoEnolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
HEAR2367Putative alcohol dehydrogenase (ADH)(part 1); Gene remnant; putative enzyme. (277 aa)
cbbAFructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
pgkPhosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phosphoglycerate kinase family. (397 aa)
HEAR2721Phosphomannomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (458 aa)
gpmA12,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa)
gpmA22,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (239 aa)
HEAR3352Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (477 aa)
Your Current Organism:
Herminiimonas arsenicoxydans
NCBI taxonomy Id: 204773
Other names: CCM 7303, DSM 17148, H. arsenicoxydans, Herminiimonas arsenicoxydans Muller et al. 2006, LMG 22961, LMG:22961, strain ULPAs1
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