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HEAR0251 HEAR0251 thrB thrB HEAR0275 HEAR0275 ttuD ttuD lpdA lpdA HEAR0804 HEAR0804 asd asd trpB trpB trpA trpA pssA pssA ask ask odhL odhL serB serB thrC thrC hom hom glyA glyA HEAR2402 HEAR2402 serC serC sgaA sgaA ilvA ilvA HEAR2940 HEAR2940 gpmA1 gpmA1 gpmA2 gpmA2 HEAR3352 HEAR3352 ectD ectD ectC ectC ectB ectB ectA ectA HEAR3420 HEAR3420 HEAR3458 HEAR3458
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
HEAR0251Putative Phosphoglycerate/bisphosphoglycerate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the phosphoglycerate mutase family. (216 aa)
thrBHomoserine kinase (HSK) (HK); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pseudomonas-type ThrB family. (322 aa)
HEAR0275Putative Choline monooxygenase with Rieske [2Fe-2S] domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (366 aa)
ttuDPutative hydroxypyruvate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (396 aa)
lpdADihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (611 aa)
HEAR0804Putative glyoxylate reductase (Glycolate reductase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)
asdAspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (368 aa)
trpBTryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (423 aa)
trpATryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (265 aa)
pssACDP-diacylglycerol-serine O-phosphatidyltransferase; Function of strongly homologous gene; enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (338 aa)
askAspartokinase (Aspartate kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. (417 aa)
odhLDihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (475 aa)
serBPhosphoserine phosphatase (PSP) (O-phosphoserine phosphohydrolase) (PSPase); Function of strongly homologous gene; enzyme. (281 aa)
thrCThreonine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (486 aa)
homHomoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (437 aa)
glyASerine hydroxymethyltransferase (Serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (414 aa)
HEAR2402NADP-dependent L-serine/L-allo-threonine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa)
serCPhosphoserine aminotransferase (Phosphohydroxythreonine aminotransferase) (PSAT); Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (363 aa)
sgaASerine--glyoxylate aminotransferase (SGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (405 aa)
ilvAThreonine dehydratase biosynthetic (Threonine deaminase); Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (507 aa)
HEAR2940Putative CDP-diacylglycerol--serine O-phosphatidyltransferase, partial; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (210 aa)
gpmA12,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa)
gpmA22,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (239 aa)
HEAR3352Putative dihydrolipoamide dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (477 aa)
ectDEctoine hydroxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (306 aa)
ectCL-ectoine synthase (N-acetyldiaminobutyrate dehydratase); Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (145 aa)
ectBDiaminobutyrate--2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (431 aa)
ectAL-2,4-diaminobutyric acid acetyltransferase (DABA acetyltransferase); Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (178 aa)
HEAR3420Putative Choline dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (537 aa)
HEAR3458Putative Phosphoglycerate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)
Your Current Organism:
Herminiimonas arsenicoxydans
NCBI taxonomy Id: 204773
Other names: CCM 7303, DSM 17148, H. arsenicoxydans, Herminiimonas arsenicoxydans Muller et al. 2006, LMG 22961, LMG:22961, strain ULPAs1
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