(11 nodes) Retromer complex network (Mastacembelus armatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	vps29	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (231 aa)
	LOC113143283	Uncharacterized protein. (335 aa)
	LOC113126067	Sorting nexin 27a. (562 aa)
	snx3	Sorting nexin 3. (163 aa)
	tbc1d5	TBC1 domain family, member 5. (916 aa)
	vps35	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (798 aa)
	vps26b	VPS26, retromer complex component B. (333 aa)
	vps26a	VPS26, retromer complex component A. (328 aa)
	snx12	Sorting nexin 12. (198 aa)
	snx7	Sorting nexin 7. (420 aa)
	SNX4	Sorting nexin 4. (437 aa)

Your Current Organism:

Mastacembelus armatus

NCBI taxonomy Id: 205130
Other names: M. armatus, Macrognathus armatus, zig-zag eel

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC113126067	LOC113143283	ENSMAMP00000000751	ENSMAMP00000000696	Sorting nexin 27a.	Uncharacterized protein.	0.822
LOC113126067	snx12	ENSMAMP00000000751	ENSMAMP00000031701	Sorting nexin 27a.	Sorting nexin 12.	0.461
LOC113126067	snx3	ENSMAMP00000000751	ENSMAMP00000010859	Sorting nexin 27a.	Sorting nexin 3.	0.461
LOC113126067	tbc1d5	ENSMAMP00000000751	ENSMAMP00000012443	Sorting nexin 27a.	TBC1 domain family, member 5.	0.551
LOC113126067	vps26a	ENSMAMP00000000751	ENSMAMP00000030063	Sorting nexin 27a.	VPS26, retromer complex component A.	0.934
LOC113126067	vps26b	ENSMAMP00000000751	ENSMAMP00000025735	Sorting nexin 27a.	VPS26, retromer complex component B.	0.822
LOC113126067	vps29	ENSMAMP00000000751	ENSMAMP00000000095	Sorting nexin 27a.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.597
LOC113126067	vps35	ENSMAMP00000000751	ENSMAMP00000014751	Sorting nexin 27a.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.682
LOC113143283	LOC113126067	ENSMAMP00000000696	ENSMAMP00000000751	Uncharacterized protein.	Sorting nexin 27a.	0.822
LOC113143283	SNX4	ENSMAMP00000000696	ENSMAMP00000034717	Uncharacterized protein.	Sorting nexin 4.	0.780
LOC113143283	snx12	ENSMAMP00000000696	ENSMAMP00000031701	Uncharacterized protein.	Sorting nexin 12.	0.940
LOC113143283	snx3	ENSMAMP00000000696	ENSMAMP00000010859	Uncharacterized protein.	Sorting nexin 3.	0.940
LOC113143283	snx7	ENSMAMP00000000696	ENSMAMP00000032197	Uncharacterized protein.	Sorting nexin 7.	0.763
LOC113143283	tbc1d5	ENSMAMP00000000696	ENSMAMP00000012443	Uncharacterized protein.	TBC1 domain family, member 5.	0.851
LOC113143283	vps26a	ENSMAMP00000000696	ENSMAMP00000030063	Uncharacterized protein.	VPS26, retromer complex component A.	0.961
LOC113143283	vps29	ENSMAMP00000000696	ENSMAMP00000000095	Uncharacterized protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.981
LOC113143283	vps35	ENSMAMP00000000696	ENSMAMP00000014751	Uncharacterized protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.991
SNX4	LOC113143283	ENSMAMP00000034717	ENSMAMP00000000696	Sorting nexin 4.	Uncharacterized protein.	0.780
SNX4	snx12	ENSMAMP00000034717	ENSMAMP00000031701	Sorting nexin 4.	Sorting nexin 12.	0.458
SNX4	snx3	ENSMAMP00000034717	ENSMAMP00000010859	Sorting nexin 4.	Sorting nexin 3.	0.458